An apparatus may be for producing nanocarriers and/or nanoformulations. A process may be for producing a nanocarrier and/or a nanoformulation with this apparatus. According to the preparation, a first liquid phase and a second liquid phase are mixed first to give a primary mixture using a static mixer. In a subsequence mixing step the primary mixture is diluted with a third liquid. An aspect of apparatus may be that the arrangement of the static mixer inside a linear pipe conducting a third liquid phase. Thus, the primary mixture exiting the mixer is instantaneously diluted with to give secondary mixture. The volume flow of the third mixture is chosen larger than the volume flow of the primary mixture. By these measures, nanocarriers with improved morphology and homogeneity are produced. Encapsulation efficiency was enhanced as well.

Multiphase mixing systems and methods for creating homogenous mixtures of solid and liquid components. A system includes an inlet pump tube configured to be disposed within a mixing vessel. The system includes a pump in fluid communication with the inlet pump tube, wherein the pump extracts a solution from the mixing vessel when the inlet pump tube is disposed within the mixing vessel. The system includes a three-way valve in fluid communication with the pump. The system includes a differential pressure outlet configured to be disposed within the mixing vessel, wherein the differential pressure outlet is in fluid communication with the pump and the three-way valve. The system is such that the extracted solution is processed through the pump and ejected into the mixing vessel through the differential pressure outlet.

A method and equipment for plant cultivation, where the plants are supplied with water, over irrigation phases of specific duration spread over a 24 h day, which water has a given content of dissolved oxygen, characterized in that use is made of a system for boosting the injection of oxygen (or of an oxygen-containing gas mixture) in the irrigation water over a first period, of given duration, of one or some of the irrigation phases in question, and in that the remainder of the time of said irrigation phase(s) in question is characterized by a content of dissolved oxygen in the water which is nominal, i.e. lower than the boosted content of the first period.

A method for improving stability and/or absorption of one or more biologically active agents including preparing formulations wherein a biologically active agent is dispersed using a homogenizer and/or a nanofluidizer; and optionally: i) enriching the formulation; and/or ii) delivering the formulations to a subject whereby the biologically active agent is absorbed by said subject, and/or iii) testing the formulation to identify suitable dosing ranges using computational modeling of biomolecular pathways to determine at least one feature selected from absorption in a cell, saturation of a cell, and potential toxicity in a cell, and/or iv) testing the formulation by monitoring with a low impact, minimally intrusive heart rate variability monitoring to enable rapid determination of neurological and physiological effects of a dosage, establishing dosing levels of the biologically active agent, and/or v) defining the corresponding metabolic effects of the dosage of the biologically active agent on the subject.

A mixing apparatus includes a material supply line, a mixing tank, a stirring device, and a transportation line. The material supply line supplies two or more kinds of materials including a liquid. The mixing tank accommodates the two or more kinds of materials that have been supplied. The stirring device stirs a mixed solution of the two or more kinds of materials inside the mixing tank. The transportation line transports the mixed solution inside the mixing tank to an outside of the mixing tank. The mixing apparatus maintains a liquid level height of the mixed solution inside the mixing tank at a level falling within a predetermined range by controlling at least one of a supply amount of the two or more kinds of materials to be supplied into the mixing tank and a transportation amount of the mixed solution to be transported to the outside of the mixing tank.

Present invention relates to an apparatus (0) for producing nanocarriers and/or nanoformulation and a process for producing a nanocarrier and/or a nanoformulation by means of this apparatus (0). According to inventive preparation, a first liquid phase (A) and the second liquid phase (B) are mixed first to give the primary mixture (A+B) by means of a static mixer (4). In a subsequence mixing step primary mixture (A+B) is diluted with a third liquid (C). An important aspect of apparatus (0) is the arrangement of the static mixer (4) inside a linear pipe (7) conducting third liquid phase (C). Thus, the primary mixture (A+B) exiting the mixer (4) is instantaneously diluted with (C) to give secondary mixture (A+B+C). The volume flow of the third mixture (C) is chosen larger than the volume flow of the primary mixture (A+B). By these measures, nanocarriers with improved morphology and homogeneity are produced. Encapsulation efficiency was enhanced as well.

Packed bed gel material cleaning vessel, has an internal processing volume, to contain the gel, delimited by a circumferential, axially extending, upright vessel wall at both axial ends sealed by a top vessel wall and an opposite bottom vessel wall, the internal processing volume is above 10 litre; sensors of the vessel monitor the filling level of the vessel. A bottom filter completely covers the vessel bottom wall A circumferential, axially extending, cylindrical vertical filter is provided a short radial distance, e.g. between 1 and 20 millimetre internally from, parallel and concentrically with, the upright vessel wall, providing a torus like flow gap concentrical with the upright vessel wall.

According to an example, a mixing device comprises a first chamber including a solute addition member and a first mixer, a second chamber including a second mixer, a printing fluid pump, and a controller operatively connected to the solute addition member, the pump, the first mixer, and the second mixer. The controller is to control the pump to move printing fluid towards the printing fluid tank based on a printing fluid density level in the printing fluid tank, to control the solute addition member to add solids based on the printing fluid density level, and to control the first mixer and the second mixer to mix the added solids with the printing fluid moved by the pump.

Methods and apparatuses for producing a substrate are described. A method and apparatus for introducing a component into a fluid supply is also presented. A method can include providing a first fluid supply. The fluid supply can be configured as a foam in some embodiments. The method can also include providing a component feed system and a supply of the component. The method can include introducing the component to a fluid supply in an eductor in some aspects. A resultant slurry including a fluid supply and the component can be transferred through a headbox. The resultant slurry can be dewatered to provide a substrate including the component.

A system and method for permitting a chemical fluid line to serve multiple downstream injection sites from a single upstream pump. One or more redundant primary chemical conduits are manifolded via a flexible joint into a plurality of sub-stream chemical conduits, each of the sub-stream chemical conduits comprising a sub-stream flow meter and an independently controlled motorized flow control valve. control computer directs each respective control valve to open and close depending on the desired flow rate of the respective downstream injection site.