A multi-component mixing device including at least a first supply of a first product and a second supply of a second product. The mixing device has a mixing chamber having at least a first inlet and a second inlet, the first supply opening into the mixing chamber at the first inlet and the second supply opening into the mixing chamber at the second inlet. The mixing device includes a nozzle arranged and adapted to inject the second product from the second supply into the mixing chamber as a flat jet. An associated mixing method is also provided.

The invention addresses the problem of providing a method for producing microparticles. Provided is a method for producing microparticles. For the first process, seed microparticles are separated in a thin film fluid that forms between at least two processing surfaces, which are disposed facing each other, which can approach or separate from each other and at least one of which rotates relative to the other, and the fluid comprising the separated seed microparticles is discharged as a discharge fluid. Subsequently, for the second process, the separated seed microparticles are grown in the discharged discharge fluid to obtain the intended microparticles. Uniform and homogeneous microparticles are obtained as a result of the microparticle producing method comprising the two process.

Provided is a continuous reaction apparatus which can precisely control the path of flow of the liquid reaction mixture in the reaction vessel. Further, provided is a continuous reaction apparatus which can efficiently mix the liquid reaction mixture in the reaction vessel. The continuous reaction apparatus comprises a plurality of mixing vessel units and a plurality of partition units. These units are connected in the state of being alternately stacked on one another. Each mixing vessel unit has an agitating blade disposed in the inner space thereof. The relationship between the inner diameter D1 of the mixing vessel unit, the height H of the mixing vessel unit, and the outer diameter d1 of the agitating blade satisfies the formula (1): 10(D1/H)1.5, and the formula (2): 0.99(d1/D1)0.7. The agitating blade is a circular disc-type agitating blade.

Systems and method for producing a small-scale mixer are provided. In some implementations, a method for includes obtaining dimensions of an at-scale mixer. The method also includes determining first dimensions of the small-scale mixer based on respective dimensions of the at-scale mixer. The method further includes determining second dimensions of the small-scale mixer independent of the dimensions of the at-scale mixer. Additionally, the method includes generating the small-scale mixer using the first dimensions and the second dimensions using a three-dimensional printer.

An air diffuser includes: a bottom panel provided in a horizontal direction in a tank in which water is filled; an air diffusion body installed to cover the bottom panel from above; and air diffusion holes arranged to penetrate through the air diffusion body, gas fed to a gap between the bottom panel and the air diffusion body is discharged into water through the air diffusion holes, and an air diffusion region of the air diffusion body where the air diffusion holes are arranged has a width equal to or larger than 10 mm and smaller than 120 mm. A method of treating water using the air diffuser includes supplying air to the air diffuser at a volume of equal to or smaller than 60 [Nm.sup.3/(m.sup.2.Math.hr)].

In a stirred tank chemical reactor the mean age of the reactor contents affects a number of properties of the product, including for example the homogeneity of the product. The mean average age of the reactor contents can be determined by constructing a transparent model of the reactor and filling it with a fluid containing a fluorescent dye and having flow properties comparable to those of the reactor in use. A light is shone on the fluid as it is stirred under reaction conditions and a clear fluid flow into the model. Pictures are taken of the reactor contents and the mean fluid age of the contents of the model are determined relative to the exit age of the contents. This approach can be applied to determine for example which reactor ports to use, what agitator to use, what flow rates to use to improve reactor function.

Initially heterogenous biopharmaceutical composition is mixed in a bag designed as a mixed bioreactor with capacity of at least 1500 liters, using an apparatus that includes a tank, the flexible and collapsible bag received in the tank and a stirring device. The device includes an impeller driven from below for initiating agitation adjacent to a tank base. Once the bag is stretched under liquid pressure, it becomes parallelepiped with a bottom wall, a top wall and a sidewall. The bag, in contact against four side panels of the tank, has a rectangular cross section including four rounded corners each spaced from the side wall.

Embodiments of the present disclosure include a process and a system for solubilizing a surfactant in supercritical carbon dioxide that include providing a turbulent flow of the supercritical carbon dioxide into which the surfactant solubilizes and injecting the surfactant into the turbulent flow of the supercritical carbon dioxide to achieve a Jet Mixing Number of 0.01 to 1.0. In one or more embodiments, a pump provides turbulent flow to supercritical carbon dioxide moving through at least a portion of piping, and an injector associated with the piping conveys the surfactant through surfaces defining a port in the injector to inject the surfactant into the turbulent flow of the supercritical carbon dioxide so as to achieve the Jet Mixing Number of 0.01 to 1.0.

Disclosed herein are methods and systems for the transportation and delivery of set-delayed cement compositions to a well site. A method of cementing may comprise preparing a set-delayed cement composition. The method further may comprise storing the set-delayed cement composition. The method further may comprise transporting the set-delayed cement composition to a well site in a containment vessel. The method further may comprise discharging the set-delayed cement composition from the containment vessel and into a wellbore.

Disclosed are a paddle discarding fully-sealed cement stirring and solidification bucket and a liquid injection and stirring method. A stirring paddle, a bucket cover, and a stirring steel bucket are first assembled and conveyed to a feeding station for cover removal and cement filling; then the stirring steel bucket is conveyed to a stirring station; after a stirring power device, a waste liquid injection device, and a breathing and exhaust device are correspondingly connected to a stirring paddle drive connection end, a waste liquid injection interface, and a breathing and exhaust device interface, injection and stirring of radioactive waste liquid are carried out in a fully-sealed environment. In the present invention, the stirring paddle is discarded in the steel bucket, thereby avoiding the problems of secondary radioactive waste liquid produced by cleaning the stirring paddle and diffusion of radioactive aerosol in the stirring process.