Provided are thermoplastic polymer particles having an aspect ratio of 1.00 or more and less than 1.05, and a roundness of 0.95 to 1.00. The thermoplastic polymer particles are formed from a thermoplastic polymer resin in a continuous matrix phase. The thermoplastic polymer particles show a peak cold crystallization temperature (T.sub.cc) at a temperature between a glass transition temperature (T.sub.g) and the melting point (T.sub.m) in a differential scanning calorimetry (DSC) curve which is derived from temperature rise analysis at 10° C./min by differential scanning calorimetry.

The present invention relates to a process for spray drying of a feed solution comprising semaglutide, said process comprising introducing the feed solution comprising semaglutide in a solvent into a spray dryer and introducing an atomising gas and a drying gas, characterised in that the spray dryer comprises a gas heater for the drying gas with an inner surface comprising iron and less than 18.5% chromium.

A fluidized bed granulator for production of urea-containing or nitrate-containing granules may include a granulator interior having granulator interior walls with a first granulator side wall, a second granulator side wall, a granulator front wall that extends transversely to the granulator side walls, and a granulator back wall that likewise extends transversely at the opposite end of the granulator interior from the granulator front wall, a horizontal perforated plate that bounds the granulator interior in a downward direction, a seed entry opening, and a granule exit opening that is disposed at a distance in front of the granulator back wall. A process for producing urea-containing or nitrate-containing granules may utilize the fluidized bed granulator.

A fluidized bed granulator for production of urea-containing or nitrate-containing granules may include a granulator interior having granulator interior walls with a first granulator side wall, a second granulator side wall, a granulator front wall that extends transversely to the granulator side walls, and a granulator back wall that likewise extends transversely at the opposite end of the granulator interior from the granulator front wall, a horizontal perforated plate that bounds the granulator interior in a downward direction, a seed entry opening, and a granule exit opening that is disposed at a distance in front of the granulator back wall. A process for producing urea-containing or nitrate-containing granules may utilize the fluidized bed granulator.

The present disclosure belongs to the technical field of gel material processing, and discloses processing equipment and a processing technology of a gel microsphere material. The processing equipment comprises a mixing barrel, wherein a motor is installed at the top of the mixing barrel; a rotating rod is arranged in the mixing barrel; the rotating rod is fixedly connected to the output end of the motor; a fan-shaped impeller is installed at the bottom end of the rotating rod; the bottom of the rotating rod communicates with a gas conveying pipe; a shunting ring is fixedly connected to the inner side wall of the mixing barrel; the bottom of the rotating rod is fixedly connected with the fan-shaped impeller; and the gas conveying pipe is arranged at the bottom of the mixing barrel to inflate a raw material solution in the mixing barrel, when bubbles float in the solution, the solution can be stirred, and then under the cooperation of the fan-shaped impeller at the bottom of the rotating rod, the raw material solution of the gel microsphere material is stirred more quickly and more uniformly in the mixing barrel compared with the raw material solution only stirred by the fan-shaped impeller.

The present disclosure belongs to the technical field of gel material processing, and discloses processing equipment and a processing technology of a gel microsphere material. The processing equipment comprises a mixing barrel, wherein a motor is installed at the top of the mixing barrel; a rotating rod is arranged in the mixing barrel; the rotating rod is fixedly connected to the output end of the motor; a fan-shaped impeller is installed at the bottom end of the rotating rod; the bottom of the rotating rod communicates with a gas conveying pipe; a shunting ring is fixedly connected to the inner side wall of the mixing barrel; the bottom of the rotating rod is fixedly connected with the fan-shaped impeller; and the gas conveying pipe is arranged at the bottom of the mixing barrel to inflate a raw material solution in the mixing barrel, when bubbles float in the solution, the solution can be stirred, and then under the cooperation of the fan-shaped impeller at the bottom of the rotating rod, the raw material solution of the gel microsphere material is stirred more quickly and more uniformly in the mixing barrel compared with the raw material solution only stirred by the fan-shaped impeller.

Method of producing prills includes providing a hollow body rotatable about a first axis, the body having a wall rotationally symmetrical around the first axis forming an interior space, the wall including nozzles; providing a second body disposed in the hollow body such that a gap exists between the hollow body and the second body; supplying liquid to the gap; generating jets of liquid from the nozzles radially outward by driving the rotational motion of the hollow body and/or second body around the first axis of rotation using a rotary drive unit; applying a reciprocal pressure excitation on the jets of liquid by moving the hollow body and/or second body along the first axis; and decoupling the rotations of the one of the hollow body and second body and a reciprocating drive-unit.

Method of producing prills includes providing a hollow body rotatable about a first axis, the body having a wall rotationally symmetrical around the first axis forming an interior space, the wall including nozzles; providing a second body disposed in the hollow body such that a gap exists between the hollow body and the second body; supplying liquid to the gap; generating jets of liquid from the nozzles radially outward by driving the rotational motion of the hollow body and/or second body around the first axis of rotation using a rotary drive unit; applying a reciprocal pressure excitation on the jets of liquid by moving the hollow body and/or second body along the first axis; and decoupling the rotations of the one of the hollow body and second body and a reciprocating drive-unit.

Disclosed are systems and methods for producing particles of organic substances, in particular nanoparticles and microparticles of active pharmaceutical ingredients, wherein the particles are collected in the aid of an extension member engaged to a collection chamber and positioning a nozzle.

Disclosed are systems and methods for producing particles of organic substances, in particular nanoparticles and microparticles of active pharmaceutical ingredients, wherein the particles are collected in the aid of an extension member engaged to a collection chamber and positioning a nozzle.