The system can include: a conduit having a first dimension with an inlet and outlet; an extruder having an inlet and an outlet located within the conduit, an extruder orifice having a second dimension that is smaller than the first dimension; a carrier fluid reservoir coupled with the conduit inlet; an extruder reservoir coupled with the extruder inlet; and a particle collector fluidly coupled with the conduit outlet, wherein the particle collector has a collector inlet with a first temperature and a collector outlet with a second temperature. The method can include flowing carrier fluid through the extrudate conduit; extruding wax with the extruder into the carrier fluid that is flowing through the extrudate conduit such that the extrudate separates into extrudate segments separated from each other by carrier fluid segments; and flowing the extrudate into the particle collector so as to form wax particles.

The subject matter of this invention relates to hydrogel compositions and, more particularly, to hydrogel compositions comprising block copolymers (BCPs) capable of self-assembly into nanoparticles for the delivery and controlled release of therapeutic cargos.

A double-chamber microcapsule includes a capsule core and a microcapsule wall encapsulating the capsule core, wherein the microcapsule wall is a thermo-sensitive polymer encapsulating the content of a second chamber; the capsule core is a pH responsive polymer encapsulating the content of a first chamber, the pH responsive polymer is obtained by polymerizing a pH responsive monomer and a cross-linking monomer; the content of the first chamber is different from the content of the second chamber, each is selected from a solid acid or a solid alkali.

A double-chamber microcapsule includes a capsule core and a microcapsule wall encapsulating the capsule core, wherein the microcapsule wall is a thermo-sensitive polymer encapsulating the content of a second chamber; the capsule core is a pH responsive polymer encapsulating the content of a first chamber, the pH responsive polymer is obtained by polymerizing a pH responsive monomer and a cross-linking monomer; the content of the first chamber is different from the content of the second chamber, each is selected from a solid acid or a solid alkali.

A fire-retardant particle comprises a core formed of an aqueous solution and one or more inorganic compounds, which comprise ammonium phosphate. The particle further comprises a waterproof shell encasing the core. In an embodiment, a method of fighting a fire comprises encasing a hydrated fire-retardant compound in a waterproof shell of a fire-retardant particle. The fire-retardant particle is deployed in an area of fire. Moisture within the waterproof shell is heated by the fire. The waterproof shell ruptures as a result of the heated moisture so as to deploy the fire-retardant compound.

A consumer product including a personal care composition providing multiple blooms of fragrance, the multiple blooms being provided for by different populations of microcapsules.

Biomedical devices for implantation with decreased pericapsular fibrotic overgrowth are disclosed. The device includes biocompatible materials and has specific characteristics that allow the device to elicit less of a fibrotic reaction after implantation than the same device lacking one or more of these characteristic that are present on the device. Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject.

The present invention relates to a method for preparing a metal powder intended for an additive manufacturing process, of the type that involves scanning a bed of powder by a near-infrared laser beam, characterized in that the method comprises: an initial step for selecting a powder, which has an optical reflectivity of higher than 70% for a wavelength ranging between 800 and 1500 nm; then a step for treating said powder, which is different from particle grafting, and which induces a physical and/or chemical surface modification of the grains of said powder, making it possible to lower its optical reflectivity, at the given wavelength. The invention also relates to the use of such a powder, the grains having, after treatment, a median grain size d50 of between 5 and 50 μm.

The invention discloses a method for preparing embryonic microspheres, a preparation mechanism, a method for preparing microspheres and a device for preparing the microspheres. The method for preparing the microspheres comprises delivering a microsphere-forming solution to a porous membrane located in a receiving liquid through a liquid transport member, to form embryonic microspheres; delivering embryo microspheres separated from the porous membrane along a channel filled with the receiving liquid, hardening the embryo microspheres to form microspheres; and collecting the microspheres. Wherein the flow rate of output liquid from the liquid transport member is controllable, so that an amount of output microsphere-forming solution per unit time is directly controlled, thereby regulating the particle size and uniformity of the generated microspheres. The present method improves the yield of the microspheres by eliminating variations in the surface tension distribution across the embryonic microspheres caused by mixing air bubbles into the embryo microspheres.

The invention discloses a method for preparing embryonic microspheres, a preparation mechanism, a method for preparing microspheres and a device for preparing the microspheres. The method for preparing the microspheres comprises delivering a microsphere-forming solution to a porous membrane located in a receiving liquid through a liquid transport member, to form embryonic microspheres; delivering embryo microspheres separated from the porous membrane along a channel filled with the receiving liquid, hardening the embryo microspheres to form microspheres; and collecting the microspheres. Wherein the flow rate of output liquid from the liquid transport member is controllable, so that an amount of output microsphere-forming solution per unit time is directly controlled, thereby regulating the particle size and uniformity of the generated microspheres. The present method improves the yield of the microspheres by eliminating variations in the surface tension distribution across the embryonic microspheres caused by mixing air bubbles into the embryo microspheres.