B01J39/05

Method for the manufacture of highly purified 68Ge material for radiopharmaceutical purposes

A method for the manufacture of highly purified .sup.68Ge material for radiopharmaceutical purposes. The invention particularly concerns the production of .sup.68Ge-API (API=Active Pharmaceutical Ingredient) solution complying with the Guidelines for good manufacturing practices (GMP). Starting material for the method of the present invention can be a .sup.68Ge stock solution of commercial or other origin as raw material. Such .sup.68Ge containing raw solutions are purified from potential metal and organic impurities originating from production processes. The radiochemical method disclosed is based on a twofold separation of .sup.68Ge from organic and metallic impurities with two different adsorbent materials. During the first separation phase .sup.68Ge is purified from both organic and metallic impurities by adsorption in germanium tetrachloride form, after which hydrolyzed .sup.68Ge is purified from remaining metallic impurities by cation exchange. The final .sup.68Ge-API-product e.g. fulfills the regulatory requirements for specifications of the GMP production of .sup.68Ge/.sup.68Ga generators.

Ion exchanger filled cartridge and metal removing column
11305272 · 2022-04-19 · ·

An ion exchanger filled cartridge accommodated inside an accommodating container of a metal removing column and in which an ion exchanger is filled is provided. The ion exchanger filled cartridge includes a cylinder portion, an upper lid in which a through hole for a liquid to be treated is formed and which is provided on an upper end of the cylinder portion, a lower lid in which a through hole for a treated liquid is formed and which is provided on a lower end of the cylinder portion, an insertion pipe connected to the lower lid, having an O-ring attached to an outer side, and inserted into a treated liquid discharge pipe provided on a bottom portion of the accommodating container of the metal removing column, and the ion exchanger filled inside the cylinder portion.

Ion exchanger filled cartridge and metal removing column
11305272 · 2022-04-19 · ·

An ion exchanger filled cartridge accommodated inside an accommodating container of a metal removing column and in which an ion exchanger is filled is provided. The ion exchanger filled cartridge includes a cylinder portion, an upper lid in which a through hole for a liquid to be treated is formed and which is provided on an upper end of the cylinder portion, a lower lid in which a through hole for a treated liquid is formed and which is provided on a lower end of the cylinder portion, an insertion pipe connected to the lower lid, having an O-ring attached to an outer side, and inserted into a treated liquid discharge pipe provided on a bottom portion of the accommodating container of the metal removing column, and the ion exchanger filled inside the cylinder portion.

Filter and metal ion removal device

To provide a filter capable of efficiently removing metal ions in a treatment liquid, and capable of easily obtaining a solution having an extremely low metal ion content. A depth filter includes a porous molded article. The porous molded article is a sintered material of mixed powder or a swollen material of the sintered material. The mixed powder contains dried gel powder and thermoplastic resin powder. The dried gel powder contains an ion exchange resin including a sulfonic acid group, and a nitrogen-containing chelating resin.

Filter and metal ion removal device

To provide a filter capable of efficiently removing metal ions in a treatment liquid, and capable of easily obtaining a solution having an extremely low metal ion content. A depth filter includes a porous molded article. The porous molded article is a sintered material of mixed powder or a swollen material of the sintered material. The mixed powder contains dried gel powder and thermoplastic resin powder. The dried gel powder contains an ion exchange resin including a sulfonic acid group, and a nitrogen-containing chelating resin.

Purification process for hydrophilic organic solvent

Methods for the removal of ionic contaminants from a hydrophilic organic solvent by a mixed bed of ion exchange resins are described. A mixed bed of ion exchange resins with gel-type strong-acid cationic ion exchange resin with a specific moisture holding capacity and gel-type anionic ion exchange resin is used in some embodiments of such methods.

Purification process for hydrophilic organic solvent

Methods for the removal of ionic contaminants from a hydrophilic organic solvent by a mixed bed of ion exchange resins are described. A mixed bed of ion exchange resins with gel-type strong-acid cationic ion exchange resin with a specific moisture holding capacity and gel-type anionic ion exchange resin is used in some embodiments of such methods.

TREATMENT OF RESIDUAL STREAMS FROM THE MANUFACTURE OF BISPHENOLS
20210363082 · 2021-11-25 ·

A method is disclosed for treating a residual stream from bisphenol manufacture, wherein the residual stream comprises unreacted phenols, bisphenol isomers, trisphenols, organic sulfides and water. The method comprises contacting at least a portion of the residual stream or a reaction product thereof with an acidic catalyst under conditions sufficient to allow acid-catalyzed hydrolysis of organic sulfides in the residual stream to the corresponding thiols and produce an effluent stream, and then distilling at least a portion of the effluent stream to recover distillate products comprising phenols and thiols and produce a bottoms product comprising bisphenol isomers and trisphenols, and having a lower content of organic sulfides than the residual stream.

METHODS FOR CHROMATOGRAPHIC PROTEIN EXTRACTION AND PURIFICATION

Disclosed herein are methods and compositions for isolating a protein fraction from a potato sample. The methods include adjusting the potato sample containing the protein fraction to a pH of about 4.0 to 5.2; and loading the potato sample onto a sulfonated epoxy resin, wherein the sulfonated epoxy resin comprising Formula (I) is adjusted to a pH of about 4.0 to 4.5. The methods also include washing the sulfonated epoxy resin and eluting the protein fraction.

Method for identifying the unit causing a raw water leak in a condenser of a thermal power plant

The present invention relates to a method for identifying the unit causing a raw water leak in a condenser of a thermal power plant consisting of n units.