Disclosed is an apparatus and method for providing asymmetric oscillations to a container. The container may include a fluid, a particle, and/or a gas. A vibration driver attached to the container provides asymmetric oscillations. A controller connected to the vibration driver controls an amplitude, frequency, and shape of the asymmetric oscillations. An amplifier amplifies the asymmetric oscillations in response to the controller. A sensor disposed on the vibration driver provides feedback to the controller.

Device for the mixing and distribution of fluids for a catalytic reactor with a downward flow, said device comprising a collection zone (A), a mixing zone (B) and a distribution zone (C) comprising a distribution plate (12) comprising at least one first zone (C1) supporting a plurality of chimneys (13) and a second zone (C2); said mixing zone (B) is comprised in an annular enclosure (15) situated in the distribution zone (C), said mixing (B) and distribution (C) zones being delimited by at least one annular wall (16) comprising at least one lateral passage section (17a, 17b) suitable for the passage of the fluids from said mixing zone (B) to the first zone (C1) of said distribution zone (C), and the second zone (C2) comprises a plurality of openings (18) suitable for the partial passage of the fluids out of the distribution zone (C).

The present invention contemplates induction of immunological tolerance thereby providing permanent allograft acceptance. This method obviates the need for a lifelong regimen of immunosuppressive agents which can increase the risk of infection, autoimmunity, and cancer. Immunological tolerance is thought to be mediated by regulatory T lymphocytes (T.sub.reg cells) with immunosuppressive capabilities. A therapeutically relevant platform comprising artificial constructs are contemplated comprising numerous soluble and surface bound T.sub.reg cell stimulating factors that may induce tolerance following allograft transplantation. Such artificial constructs, being the size of a cell, have surface bound monoclonal antibodies specific to regulatory T-cell surface moieties and encapsulated soluble regulatory T-cell modulating factors.

Disclosed is an apparatus and method for providing asymmetric oscillations to a container. The container may include a fluid, a particle, and/or a gas. A vibration driver attached to the container provides asymmetric oscillations. A controller connected to the vibration driver controls an amplitude, frequency, and shape of the asymmetric oscillations. An amplifier amplifies the asymmetric oscillations in response to the controller. A sensor disposed on the vibration driver provides feedback to the controller.

Provided is a system for the hydroconversion of heavy oils essentially consisting of a solid accumulation reactor and a stripping section of the products of hydroconversion outside or inside the reactor itself.

Herein disclosed is a system for producing an organic, the system including at least one high shear mixing device having at least one rotor and at least one stator separated by a shear gap, wherein the shear gap is the minimum distance between the at least one rotor and the at least one stator; a pump configured for delivering a fluid stream comprising liquid medium and light gas to the at least one high shear mixing device, wherein the at least one high shear mixing device is configured to form a dispersion of the light gas in the liquid medium; and a reactor comprising at least one inlet and at least one outlet, wherein the at least one inlet of the reactor is fluidly connected to the at least one high shear mixing device, and wherein the at least one outlet is configured for extracting the organic therefrom.

Herein disclosed is a system for producing an organic, the system including at least one high shear mixing device having at least one rotor and at least one stator separated by a shear gap, wherein the shear gap is the minimum distance between the at least one rotor and the at least one stator; a pump configured for delivering a fluid stream comprising liquid medium and light gas to the at least one high shear mixing device, wherein the at least one high shear mixing device is configured to form a dispersion of the light gas in the liquid medium; and a reactor comprising at least one inlet and at least one outlet, wherein the at least one inlet of the reactor is fluidly connected to the at least one high shear mixing device, and wherein the at least one outlet is configured for extracting the organic therefrom.

Disclosed is an apparatus and method for providing asymmetric oscillations to a container. The container may include a fluid, a particle, and/or a gas. A vibration driver attached to the container provides asymmetric oscillations. A controller connected to the vibration driver controls an amplitude, frequency, and shape of the asymmetric oscillations. An amplifier amplifies the asymmetric oscillations in response to the controller. A sensor disposed on the vibration driver provides feedback to the controller.

A multi-phase combination reaction system has at least one fixed bed hydrogenation reactor. The fixed bed hydrogenation reactor has, arranged from top to bottom, a first hydrogenation reaction area, a gas-liquid separation area, a second hydrogenation reaction area and a third hydrogenation reaction area. The gas-liquid separation area is provided with a raw oil inlet. A hydrogen inlet is provided between the second hydrogenation reaction area and the third hydrogenation reaction area. The system is capable of simultaneously obtaining two fractions in one hydrogenation reactor.