The invention relates to the use of a microdevice for the modification of protein with carbohydrate. Preferably for the glycation of protein with a mono-, di-, oligo- or polysaccharide(s). The invention also relates to the process for modifying protein with carbohydrate in a microdevice. The invention also relates to a process for preparing a food, feed, personal care, cosmetic, pharmaceutical, paper or corrugated board product comprising the process steps to prepare the modified protein and the step of combining the modified protein with at least one other ingredient.

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

Disclosed herein are methods for preparing nanomaterials, such as nanoparticles. The methods can involve jet-mixing two or more precursor solutions to form the nanomaterials. By rapidly mixing the precursor solutions, nanomaterials of improved quality and uniformity can be prepared in high yield (e.g., in yields of at least 85%). The methods are also scalable, and allow for the continuous production of nanomaterials. Also provided are jet-mixing reactors that can be used to prepare nanomaterials using the methods described herein.

A micronozzle device can include at least one layer having a plurality of nozzle exits for delivering a mixture of a first fluid and a second fluid, at least one first-fluid header layer having a plurality of first microchannels for receiving the first fluid, at least one first-fluid via layer adjacent the at least one first-fluid header layer to receive the first fluid and direct it to respective ones of the plurality of nozzle exits, at least one second-fluid header layer having a plurality of second microchannels for receiving the second fluid, at least one second-fluid via layer adjacent the at least one second-fluid header layer to receive the second fluid and direct it respective ones of the plurality of nozzle exits, and a plurality of first curtain-gas nozzles located at a first side of the micronozzle device and a plurality of second curtain-gas nozzles located at a second side of the micronozzle device.

The present invention refers to a system for the process of synthesis of zeolite nanoparticles in continuous flow wherein the processes of mixing, aging and crystallization are integrated, to reduce the synthesis time. The system has a microfluidic device of the 3D crossing channels micromixer type, consisting of microchannels built in series, used to generate the reaction mixture; buffer system with addition of seeds; and a heated tubular reactor which, in turn, is used for crystallization, which takes place through a continuous hydrothermal process.

The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control, The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules.

A flow reactor has a module having a process fluid passage with an interior surface, a portion of the passage including a cross section along the portion having a cross-sectional shape, and a cross-sectional area with multiple minima along the passage. The cross-sectional shape varies continually along the portion and the interior surface of the portion includes either no pairs of opposing flat parallel sides or only pairs of opposing flat parallel sides which extend for a length of no more than 4 times a distance between said opposing flat parallel sides along the portion and the portion contains a plurality of obstacles distributed along the portion.

A continuous acoustic chemical microreactor system is disclosed. The system includes a continuous process vessel (CPV) and an acoustic agitator coupled to the CPV and configured to agitate the CPV along an oscillation axis. The CPV includes a reactant inlet configured to receive one or more reactants into the CPV, an elongated tube coupled at a first end to the reactant inlet and configured to receive the reactants from the reactant inlet, and a product outlet coupled to a second end of the elongated tube and configured to discharge a product of a chemical reaction among the reactants from the CPV. The acoustic agitator is configured to agitate the CPV along the oscillation axis such that the inner surface of the elongated tube accelerates the one or more reactants in alternating upward and downward directions along the oscillation axis.

Provided are a method for producing organic material microparticles and a method for modifying organic material microparticles, whereby it becomes possible to improve the crystallinity of organic material microparticles or achieve the crystal transformation of the organic material microparticles while preventing the growth of the organic material microparticles in a solvent. A surfactant is added to a solvent that is capable of partially dissolving organic material microparticles, and then the organic material microparticles are reacted with the solvent. In this manner, it becomes possible to improve the degree of crystallization of the organic material microparticles or achieve the crystal transformation of the organic material microparticles without substantially altering the particle diameters of the organic material microparticles.

A continuous acoustic chemical microreactor system is disclosed. The system includes a continuous process vessel (CPV) and an acoustic agitator coupled to the CPV and configured to agitate the CPV along an oscillation axis. The CPV includes a reactant inlet configured to receive one or more reactants into the CPV, an elongated tube coupled at a first end to the reactant inlet and configured to receive the reactants from the reactant inlet, and a product outlet coupled to a second end of the elongated tube and configured to discharge a product of a chemical reaction among the reactants from the CPV. The acoustic agitator is configured to agitate the CPV along the oscillation axis such that the inner surface of the elongated tube accelerates the one or more reactants in alternating upward and downward directions along the oscillation axis.