A flow reactor has a module having a process fluid passage with an interior surface, a portion of the passage including a cross section along the portion having a cross-sectional shape, and a cross-sectional area with multiple minima along the passage. The cross-sectional shape varies continually along the portion and the interior surface of the portion includes either no pairs of opposing flat parallel sides or only pairs of opposing flat parallel sides which extend for a length of no more than 4 times a distance between said opposing flat parallel sides along the portion and the portion contains a plurality of obstacles distributed along the portion.

A method for the continuous flow synthesis of (R)-4-halo-3-hydroxy-butyrate using a micro-reaction system. The micro-reaction system includes a micro-mixer, a certain number of micro-reaction units that are successively connected in series, a pH regulating system and a back pressure valve. The micro-reaction unit is composed of a micro-channel reactor and a pH regulator that are sequentially connected with each other. A substrate solution containing halogenated acetoacetate and a biocatalyst solution are simultaneously pumped into the micro-reaction system to enable continuous flow biocatalytic asymmetric reduction reaction of the halogenated acetoacetate to obtain the target product (R)-4-halo-3-hydroxy-butyrate.

A Liquid, comprising an hydrophobic flavonoid derivative electrochemically non-active, that is capable of restoring its electrochemical activity, the concentration of the flavonoid derivative being 10 ppm by weight or less, and an organic substance in an amount of 90% by weight or more.

A method for continuously processing at least two liquid feed streams is provided. A system for continuously processing at least two liquid feed streams is also provided.

Provided is a method of mixing first and second liquids having mutual solubility inside a mixing flow channel formed by a micro flow channel. This method includes: causing the first and second liquids to be joined to each other inside the mixing flow channel; and forming a slug flow, in which mixing subject cells (60) formed by the joined liquid and insoluble fluid cells (63) formed by an insoluble fluid are alternately arranged, inside a flow channel at the downstream side of an insoluble fluid supply position in a manner such that the insoluble fluid having insolubility with respect to both mixing subject liquids is supplied to the joined liquid flowing through the flow channel in a direction intersecting the flow channel so that the joined liquid is divided with a gap therebetween, thereby mixing the first mixing subject liquid and the second mixing subject liquid contained in each mixing subject cell inside the downstream flow channel.

A reactor includes: a reaction-side flow passage through which a fluid as a reaction object flows; and a catalyst structure provided in the reaction-side flow passage. The catalyst structure includes: a body part formed in a raised and depressed plate shape to partition the reaction-side flow passage into a plurality of flow passages disposed side by side in a direction perpendicular to a flow direction of the fluid; a catalyst carried on the body part to promote a reaction of the fluid; and one or more communication holes (grooves) to make the plurality of flow passages partitioned by the body part communicate with each other.

Provided a high-pressure homogenizer comprising a channel module comprising a microchannel through which an object for homogenization passes, wherein the microchannel is provided with a first flow channel and a second flow channel sequentially arranged along the direction through which the object passes, the first flow channel is provided with a plurality of first baffles disposed so as to partition the microchannel into a plurality of spaces, the second flow channel is provided with a plurality of second baffles disposed so as to partition the microchannel into a plurality of spaces, and at least one of the first baffles is provided to be positioned between two adjacent second baffles.

The present invention provides a method for manufacturing a polymer by a flow-type reaction. The method includes introducing a liquid A of an anionic polymerizable monomer, a liquid B of an anionic polymerization initiator, and a polymerization terminator into different flow paths, allowing the liquids to flow in the flow paths, allowing the liquid A and the liquid B to join together, subjecting the monomer to anionic polymerization while the liquids having joined together are flowing to downstream in a reaction flow path, and allowing a solution, which is obtained by the polymerization reaction and flows in the reaction flow path, and the polymerization terminator to join together so as to terminate the polymerization reaction and to obtain a polymer having a number-average molecular weight of 5,000 to 200,000. A static mixer is disposed in the reaction flow path, and a polymer having a number-average molecular weight equal to or greater than 2,000 is introduced into an inlet port of the mixer. The present invention also provides a flow-type reaction system suitable for performing the manufacturing method.

Disclosed herein is a device and method for changing the conditions of a solution flowing in a serial path. In particular, disclosed herein is a device that includes a chemical reactor, a first system, and a second system that are each serial to one another. Each of the first system and the second system include a mixing chamber, a solvent reservoir, a solvent pump, and one or more detectors. Also disclosed herein is a method for changing the condition of a solution that includes flowing a liquid sample in a path, serially mixing the sample with at least two discrete solvents while it flows through the path, and detecting the condition of the sample after it is mixed with each solvent.

A method of preparing a Metal Organic Framework (MOF) with an acoustically-driven microfluidic platform, the method comprising: depositing a liquid comprising MOF precursors on a piezoelectric substrate of an acoustic microfluidic platform, the MOF precursors comprising a metal ion and an organic ligand, applying acoustic irradiation to the liquid to induce azimuthal liquid recirculation, which causes formation of the MOF within the liquid, and isolating the MOF.