A solid phase extraction column, preparation method therefor, and pre-processing method of chemical sample based on solid phase extraction column. The solid phase extraction column includes a separation column, and a solid phase extraction agent tilled within the separation column. The solid phase extraction agent is graphene or modified graphene. The solid phase extraction column is prepared by loading the solid phase extraction agent into the separation column, and vibrating to compact the solid phase extraction agent. The solid phase extraction column is used to pre-process a chemical sample to realize a highly effective separation effect. The problem of data distortion caused by being unable for a target component to be detected in a subsequent detection or being unable to detect a real value, is avoided.

Provided is a packing material for HILIC columns for more accurately and more easily performing oligosaccharide analysis by liquid chromatography; an HILIC column which is filled with the packing material for HILIC columns; and a method for analyzing an oligosaccharide with use of this packing material for HILIC columns A packing material for HILIC columns according to the present invention is composed of particles, each of which is obtained by reacting glycidol to a hydroxyl group of a porous cross-linked polymer base material having the hydroxyl group, and which have a hydrophilicity index of 2.30 or more and a surface-pH index of from 0.95 to 1.05.

Methods and for treatment of cancer and other diseases including complications from late stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed. The method can also be effective in treating rheumatoid arthritis, scleroderma, hepatitis, sepsis, the Epstein-Barr virus, and patients with life threatening complications from other viruses, including the COVID-19 virus. A method for removing viruses from the blood supply in an external circuit is also presented.

An embodiment of the present invention relates to an adsorbent which contains a fine particle compound containing an aluminosilicate compound and activated carbon particles, wherein the fine particle compound containing an aluminosilicate compound has a specific surface area of 300 m.sup.2/g or more and an average particle size of 10 to 200 μm and includes particles having a particle size of 10 μm or less in volume particle size distribution at 10 volume % or less, and the activated carbon particles have a mode diameter of 0.06 to 0.6 mm.

The present invention relates to a hydroxyapatite and/or tricalcium phosphate powder characterized in that it has undergone at least one sintering step at a temperature between 400° C. and 600° C. The invention also relates to a process for preparing such a powder, and to a composition comprising such a powder for use as an anti-tumour auto-vaccine and particularly in the treatment of the following pathological conditions: osteosarcoma, B or T lymphoma, mammary tumour, melanoma, haemangiosarcoma, mastocytoma, fibrosarcoma, brain tumours and schwannoma in a subject. The present invention also covers a drug combination comprising the composition of the invention and at least one second therapeutic agent, preferably an anti-tumour agent and/or a radiotherapeutic agent.

Water-absorbent resin particles having a feeding retention rate of 10% or more are disclosed, the feeding retention rate being represented by the following formula using a feeding rate through a dry powder measured by a method including the steps (A), (B), and (C) in this order, and a feeding rate through a swollen gel measured by a method including the steps (A), (B), (D), and (E) in this order.

Feeding retention rate (%)=(feeding rate through swollen gel/feeding rate through dry powder)×100

A method for producing a fraction of xenon radioisotopes, comprising the steps of dissolving enriched uranium targets forming a slurry and a gaseous phase containing xenon radioisotopes, isolating the xenon radioisotopes using zeolite doped with silver, preferably chosen from the group consisting of aluminosilicates doped with silver, titanosilicates doped with silver and mixtures thereof, and recovering the fraction of xenon radioisotopes, in particular Xe-133.

A porous formed article includes an organic polymer resin and an inorganic ion adsorbent and having the most frequent pore size of 0.08 to 0.70 μm measured with a mercury porosimeter. Such a porous formed article can be prepared by crushing and mixing a good solvent for the organic polymer resin and the inorganic ion adsorbent to obtain slurry; dissolving the organic polymer resin and a water-soluble polymer in the slurry; shape-forming the slurry; promoting coagulation of the shape-formed product by controlling the temperature and humidity of a spatial portion coming into contact with the shape-formed product, until the shape-formed product is coagulated in a poor solvent; and coagulating the coagulation-promoted shape-formed product in a poor solvent. A production apparatus can be used to prepare such a porous formed article.

Provided is a carrier which has excellent pressure resistance, and even when a protein ligand is not immobilized thereon, has a high dynamic binding capacity to a target substance, and has a high performance of separating a target substance from a biological sample.

The carrier includes a polymer having a crosslinked structure containing a divalent group represented by the following Formula (1):

##STR00001## wherein R.sup.1 to R.sup.4 independently represent a single bond or a divalent hydrocarbon group, R.sup.5 and R.sup.6 independently represent a hydrogen atom or a hydrocarbon group, X represents a thio group, a sulfinyl group, a sulfonyl group, an oxy group, >N(—R.sup.31), >Si(—R.sup.32).sub.2, >P(—R.sup.33), >P(═O)(—R.sup.34), >B(—R.sup.35), or >C(—R.sup.36).sub.2 (R.sup.31 to R.sup.36 independently represent a hydrogen atom or hydrocarbon group), and * represents a bond, with a proviso that when both R.sup.1 and R.sup.3 are a divalent hydrocarbon group, R.sup.1 and R.sup.3 may form a ring together with an adjacent carbon atom, and when both R.sup.2 and R.sup.4 are a divalent hydrocarbon group, R.sup.2 and R.sup.4 may form a ring together with an adjacent carbon atom.

A method for the separation of C4 olefin mixtures using anion-pillared hybrid porous materials as physical adsorbents is provided. The anion-pillared hybrid porous material was constructed by metal ions (M), organic ligand (L), and inorganic anion (A), forming a three-dimensional structure (A-L-M). C4 olefin mixtures contact with hybrid porous materials in certain ways, then each single C4 olefin monomer can be obtained. The pore size of anion-pillared hybrid porous materials and the spatial configurations of the anions within the pores can be fine-tuned and pre-designed. C4 olefins with different size and shape can be efficiently separated by the anion-pillared hybrid porous materials through shape recognition and size-sieving mechanism.