The invention is a method of venting the degradation products of an ascorbic acid containing composition. This prevents a build-up of carbon dioxide and may prolong the life of the packaging. The packaging includes an impermeable container and a semi-permeable top, which allows carbon dioxide to vent over time. When the composition includes water, the surface area of semi-permeable material contacting the composition is reduced to lessen water vapor loss.

The disclosure provides an attachment structure of a pipette and a fluid injecting attachment, which includes a first cylindrical hole into which a tip end portion having a tapered shape of the pipette is inserted, on one end side of an attachment main body, and a second cylindrical hole that is communicated with the first cylindrical hole and out through which fluid inside the pipette flows, on the other end side, and a step portion between the first cylindrical hole and the second cylindrical hole due to the second cylindrical hole being formed with a smaller diameter than the first cylindrical hole, the tip end portion of the pipette is inserted through the first cylindrical hole, and while the tip end portion is inserted, the second cylindrical hole has a crush allowance farther toward a tip end side than the tip end portion.

A metering head for receiving and metering at least two media, having at least two media inlets, one or multiple dispensing terminals, and fluid lines connecting the media inlets to the one or multiple dispensing terminals. The one or multiple dispensing terminals each have at least two fluidically separated media outlets. A metering system, having a metering head, at least one connecting element for fluidically connecting the metering head to a carrier substrate or to a microfluidic cartridge, and optionally a connection piece, wherein the dispensing terminal is designed to receive the connecting element directly or to receive the connecting element indirectly via the connection piece.

A system and associated method for concentrating and separating components of different densities from fluid containing cells using a centrifuge includes a container defining a cavity for receiving the fluid. The container has a top, a sidewall extending from the top, and a bottom disposed opposite the top and in sealing engagement with the sidewall. An insert is slidably disposed in the cavity of the container and defines a lumen through the insert. The lumen, which includes a hole and a funnel-shaped upper portion in fluid communication with the hole, forms an open fluid path between opposite ends of the insert. The insert has a density such that upon centrifugation a selected component of the fluid resides within the lumen. A container port is disposed in the top of the container to transfer the fluid into the container and to withdraw a fluid component other than the selected component from the container. The system includes a manifold that includes a manifold port, a vent to vent the container, and a connector to couple to the container port. A cannula is receivable in the manifold port and extendable through the container port into the container and into the lumen of the insert to withdraw the selected component from the lumen.

In an apparatus for automatically filling a pipette according to the present invention, only a predetermined air is supplied to a pipette assembly to which a substance is discharged, even if an excessive operation force is applied by a user, so it is possible to prevent a waste of the substance being unnecessarily discharged.

The present invention relates to a device and method for easy collection, dilution, mixing and dispensing of a liquid specimen in a self-contained system. The present invention can be used in combination with numerous testing means for performing chemical, biochemical or biomedical qualitative or quantitative assays in the field of both clinical and hygiene testing.

Methods of concentrating beads in a droplet and/or loading beads on a fluidic device are provided, including among other things, a method of concentrating beads in a droplet, the method comprising: (a) providing a droplet actuator comprising: (i) an interior droplet operations volume; and (ii) a reservoir exterior to the interior volume; (iii) a droplet established in a liquid path extending from the reservoir into the interior volume; (b) providing magnetically responsive beads in the portion of the droplet which is in the reservoir; (c) magnetically attracting the magnetically responsive beads through the liquid path into the portion of the droplet which is in the interior volume; and (d) forming a droplet comprising one or more of the magnetically responsive beads in the interior volume.

A pipette device, including a container having a predetermined space therein, in one end of which a nozzle is formed and the other end of which is opened; a first fixing member whose one end is detachably coupled to the other end of the container; a second fixing member coupled to the other end of the first fixing member; and a pumping member that is inserted into the second fixing member such that an opened end portion faces the other end of the container and delivers internal air into the container by changing shape when it is pressed, wherein the opened end portion of the pumping member is fixed between the first fixing member and the second fixing member by coupling of the first fixing member and the second fixing member.

Packaging and dispensing device comprising a receptacle (2) and a pipette (31) designed to be inserted into the receptacle in order to permit the collection of a dose of product, the pipette being connected to a closure member (3) for closing the receptacle, characterized in that the closure member is provided with a piston pump (28) designed to aspirate the liquid into the pipette during the passage of this closure member from a closed position to an opened position of the receptacle, the pump being equipped with a push button (5) in order to permit the aspiration of product when the closure member is not in the closed position.

A microreactor array platform and method for sealing a reagent in microreactors of an array of microreactors are provided. The microreactor array platform includes an array of microreactors, and a sealing film having a first surface and an opposite second surface, the sealing film configured to movably seal the array of microreactors. The microreactor array platform also includes an injector for delivering a reagent into the array of microreactors via a fluid path between the array and the second surface of the sealing film, and an applicator for directing a sealing liquid against the first surface of the sealing film. The microreactor array platform further includes a system for creating a pressure differential between the reagent in the injector and a space between the array of microreactors and the second surface of the sealing film.