The manual dosing device (1) comprises the main body (3) that can be screwed to the fluid discharge unit (4), the detent connection (10) being provided alongside the screw connection (6) for removably connecting the main body (3) to the fluid discharge unit (4), which detent connection is locked by connecting the main body (3) and the fluid discharge unit (4) together (cf. FIG. 5).

Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect and identify. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.

A multiple-antenna positioning system with a single drive element, providing reduced weight and complexity over systems that have a drive element for each antenna. In certain examples, each antenna can be coupled with a rotating spindle, with each antenna spindle being coupled with a pair of link arms. By driving a single drive spindle, each of the antenna spindles in the system can be rotated by the associated pair of link arms. The link arms can have an adjustable length, such as through a turnbuckle mechanism, to reduce backlash in the system, and in some examples can apply a preload to the system. By reducing backlash, the multiple antenna positioning system can have improved responsiveness to a rotation of the single drive element, as well as improved stability of the positioning of each antenna when the drive element is held in a fixed position.

In order to be able to adapt a manual dosing device (1), in particular a pipette (2), to differently sized hand dimensions, the manual dosing device (1) at whose main body (3) at least one grip (5) or exchangeable grip is releasable, fastenable or fastened is proposed. Adaptation of the manual dosing device (1) to users having different hand sizes can be performed by removing the grip (5) or by changing the grip (5) and replacing the grip (5) with a grip (5) having different dimensions (FIG. 1).

A multiple-antenna positioning system with a single drive element, providing reduced weight and complexity over systems that have a drive element for each antenna. In certain examples, each antenna can be coupled with a rotating spindle, with each antenna spindle being coupled with a pair of link arms. By driving a single drive spindle, each of the antenna spindles in the system can be rotated by the associated pair of link arms. The link arms can have an adjustable length, such as through a turnbuckle mechanism, to reduce backlash in the system, and in some examples can apply a preload to the system. By reducing backlash, the multiple antenna positioning system can have improved responsiveness to a rotation of the single drive element, as well as improved stability of the positioning of each antenna when the drive element is held in a fixed position.

In order to increase the compatibility of a pipetting system tip with various types of cones, the invention provides a tip comprising a first group of first cone retention elements defining a first maximum outer diameter; a second group of second cone retention elements defining a second maximum outer diameter; a third group of third cone retention elements defining a third maximum outer diameter. The first maximum outer diameter and the second maximum outer diameter being different so as to together define a first tip portion having a first conicity, and the second maximum outer diameter and the third maximum outer diameter being different so as to together define a second tip portion having a second conicity smaller than the first conicity.

Examples disclosed herein relate to a device. Examples to determine a dispense routine for a default dilution of a compound according to a dispense request identifying a second dilution of the compound, and a dispense engine to control the dispense device to dispense at least a portion of the default dilution of the compound according to the dispense routine. In examples, the dilution engine is to determine the dispense routine by comparing the second dilution to the default dilution to determine whether the default dilution is dilutable to the second dilution.

Examples disclosed herein relate to a device. Examples devices include a dispense routine engine to determine a first dispense routine for a first compound in a first chamber and a second compound in a second chamber. The dispense routine engine to determine a second dispense routine for the first compound and the second compound in response to a cancel chamber request for the second chamber and a chamber designation request for the second compound in a third chamber. Example devices include a dispense engine to control the dispense device to cancel dispensing of the second compound from the second chamber and to dispense at least a portion of the first compound from the first chamber and at least a portion of the second compound from the third chamber according to the second dispense routine.

Disclosed is a liquid discharging nozzle, including a needle stem having a hollow chamber and an outlet end located at one end of the needle stem, an angle between a normal line of an end surface of the outlet end of the liquid discharging nozzle and an extension direction of the needle stem is equal to or smaller than 90. Further disclosed are a motion controlling mechanism, a microdroplet generating device and method, a liquid driving mechanism and method, a microdroplet generating method, and a surface processing method of a liquid discharging nozzle.

Aspects of the present disclosure relate to a method and/or a device for carrying out chemical, biochemical and/or immunochemical analyses of liquid samples, which are present in a sample store of an automatic analyzer, with the aid of liquid reagents which are present in at least one reagent store of the analyzer. In one example embodiment, the automatic analyzer includes cuvettes, a first pipettor, a device with an optical measurement unit, a device for heterogenous immunoassays, a cuvette washing unit, a needle washing unit, a temperature control unit.