The automated pipette manipulation system of the present invention allows for the automated manipulation of any pipette commercially available to aspire and dispense liquids in a chemical or biochemical laboratory setting. Measuring the amount of liquid aspired or dispensed by a pipette is conducted by a load sensor that records the starting point of the displacement of a pushbutton of said pipette and a motor that drives the displacement of said pushbutton a predetermined distance past the starting point that corresponds to a predetermined volume of liquid aspired or dispensed by said pipette. The automated pipette manipulation system of the present invention further detects whether a pipette tip is attached to said pipette and then automatically ejects said pipette tip at the end of a liquid handling process.

In one example in accordance with the present disclosure, a fluid ejection device is described. The fluid ejection device includes a vertical support and an interface movably coupled to the vertical support. The interface is to receive an ejection head. The fluid ejection device also includes an ionizer coupled to the interface to electrostatically neutralize a substrate.

The invention relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another, where the wells contain different assay reagents. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient. Concurrently assaying a control allows modification of assay results based on measured field conditions.

The present invention provides a rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate. A distillation flask is improved into a structure having a liquid discharge opening formed at the bottom, and/or a spherical collecting flask is improved into a structure having a liquid release opening formed at the bottom. Concentrated liquid and/or distillate can be discharged without dismounting the distillation flask and/or the collecting flask. In addition, fine metering scale tubes and quantitative capacity increase units are disposed at the liquid discharge opening and/or the liquid release opening, there is a valve on the top and another valve on the bottom of each tube, so that the constant subtle changes of the amount of concentrated liquid and/or distillate can be observed, and an accurate amount of concentrated liquid and/or distillate can be discharged.

An adjustable volume sampling system is disclosed for aseptically retrieving a sample volume of a fluid from an origination container. The system includes a sampling container. A cap is removably attached to the sampling container so as to close off the open top. The cap includes two ports. A first tube is attached to one of the ports. An elongated diptube extends through port into the sampling container and an upper end of the diptube is located inside a portion of the first tube. The diptube can be raised and lowered relative to the sampling container by pinching an stretching the first tube. Syringes are provided for expelling excess material from the sampling container.

An on-demand vapour generator includes a vapour chamber configured to produce a vapour and a vapour absorption assembly configured to receive flows of vapour from the vapour chamber. The vapour absorption assembly includes a first vapour-permeable passage having a passage outlet and at least one second vapour-permeable passage that is closed. When vapour absorption assembly receives a flow of vapour from the vapour chamber, the flow of vapour passes through the first vapour-permeable passage to the passage outlet at least substantially without absorption of vapour from the flow of vapour. However, when a flow of vapour is not received from the vapour chamber, vapour entering the vapour absorption assembly from the vapour chamber passes into the first vapour-permeable passage and the at least one second vapour-permeable passage and is at least substantially absorbed.

Provided is an automatic analysis device that avoids carryover and prevents deterioration of analysis performance without controlling reaction cell position. This automatic analysis device is provided with: a reaction cell in which a sample and a reagent are mixed and allowed to react; a light source that radiates light onto the mixed liquid of the sample and the reagent, which has been dispensed into the reaction cell; a detector that detects the light radiated from the light source; and a cleaning mechanism that cleans the reaction cell. The cleaning mechanism includes an intake nozzle that draws in liquid from the reaction cell and a discharge nozzle that discharges the liquid into the reaction cell; the intake nozzle and the discharge nozzle can move vertically; and the intake nozzle is cleaned by lowering the intake nozzle into the reaction cell, in which a cleaning liquid or cleaning water have been accumulated, without drawing in the cleaning liquid or the cleaning water.

An electronic dosing drive comprising a support structure, a threaded spindle with an external thread for driving a plunger, at least one first guide element is firmly connected, and is guided parallel to the threaded spindle on a second guide element, a spindle nut having an internal thread is engaged with the external thread of the threaded spindle, an electric drive motor having a motor shaft is coupled with the spindle nut and is attached to the support structure, an electric control apparatus is connected to the electric drive motor, where the external thread of the threaded spindle has multiple threaded areas that are separated from each other by first flattenings on their circumference extending in the longitudinal direction, and the first flattenings have guide areas that abut the core diameter of the internal thread of the spindle nut.

Systems and methods for nesting refill filtered pipette tips to reduce storage space and plastic waste are provided herein. Embodiments include a lower filtered refill wafer comprising a lower plurality of refill filtered pipette tips in a nested filtered pipette tip rack, the lower filtered refill wafer comprising the lower plurality of refill filtered pipette tips having holes between top portions of the lower plurality of refill filtered pipette tips. Various embodiments further include an upper filtered refill wafer comprising an upper plurality of refill filtered pipette tips nested into the holes between the top portions of the lower plurality of refill filtered pipette tips, the nesting of the upper filtered refill wafer thereby reducing storage space for the nested filtered pipette tip rack compared with storage space for a filtered pipette tip rack that is not nested.

A multiple sample automatic dosing and cleaning system comprising a first receiving carousel for sequentially receiving multiple samples in sample cups for automatic sequential filling a dosing head. The receiving carousel is rotated around its axis and synchronized with the dosing device. Each destination cup is weighed empty on a balance scale in the destination carousel having openings for multiple cups. The destination carousel has means for rotation movement and vertical and horizontal movement. The destination carousels empty and tared cups placed on the balance scale receive the samples and flux for automatic dosing. A cleaning vacuum device is used to clean the dosing head every time each sample is dosed for integrity sample dosing. The carousels are serviced by gantry support which provides linear and vertical movement of the dosing device.