The invention relates to a method and a system for providing fluids, comprising two components, wherein a first component is a container with at least one first reservoir for taking up a fluid and a second reservoir for ventilation of the system, wherein said first and second reservoir are sealed with a seal, and a second component which is a dock for taking up the container, wherein the dock comprises an inner bottom surface comprising first formations for fluid piercing of the container's at least one first reservoir for taking up a fluid and second formations for piercing of the container's second reservoir for ventilation, and wherein said inner bottom surface is a drain plate comprising a drain, wherein the container has fins on its outer edge which engage into two parallel arranged recesses at the inner side surface of the dock for fixing the container within the dock in a first position when the fins of the container engage in a first recess which is a storage snap fit or a second position when the fins of the container engage in second recess at the inner side surface which is a retain snap fit.

Described herein are cassettes and methods for using these cassettes for cryopreserving biomaterials (e.g., a bioengineered construct or natural tissue sample) by vitrification while reducing or preventing the loss of viability associated with conventional preservation methods.

Provided herein are a system, kit and methods that allow quick and precise detection, identification and quantification of analytes in liquid samples. The kit may be used in automated and pre-programmed singleplexed and multiplexed detection and quantification of one or more analytes in a liquid samples. The kit may include a chip caddy, consumable assay chips, an electrode assembly, an electrical connector assembly, one or more cables, a voltage supply, a vacuum pump, a vacuum trap, custom-designed manifolds, one or more buffers, reagents and instructions for use.

The present invention provides methods and devices for simple, low power, automated processing of biological samples through multiple sample preparation and assay steps. The methods and devices described facilitate the point-of-care implementation of complex diagnostic assays in equipment-free, non-laboratory settings.

An analytical device for automated determining of a measured variable of a liquid sample, includes: a base module; a replaceable cassette connectable with the base module and having at least one liquid container connectable via a fluid line with a measuring cell and containing a reagent to be added to the liquid sample for forming a measured liquid; and a measuring transducer for registering measured values correlated with the measured variable for the measured liquid accommodated in the measuring cell. The cassette has, associated with the at least one liquid container, a fluid coupling apparatus having a primary component and a secondary component and serving for producing a connection of the fluid line with the liquid container.

Fluidic cartridge including a liquid container having a reservoir configured to hold a liquid. The liquid container includes an interior surface. The fluidic cartridge also includes a transfer tube that extends from the interior surface to a distal end. The distal end includes a fluidic port that is in flow communication with the reservoir through the transfer tube. The transfer tube has a piercing segment that includes the distal end. The fluidic cartridge also includes a movable seal that is engaged to the piercing segment of the transfer tube and configured to slide along the piercing segment from a closed position to a displaced position during a mating operation. The movable seal blocks flow of the liquid through the fluidic port when in the closed position. The piercing segment extends through the movable seal when in the displaced position.

A sample analysis cup assembly, system and method for purging including a cell body, including a top end; a bottom end; a cell body wall extending axially from the top end to the bottom end; a transverse wall adjacent the top end, including a plurality of apertures extending therethrough; and a raised portion on the transverse wall including a central aperture extending therethrough; a rotatable cap, including a top surface; a bottom surface; and a series of apertures extending from the top surface through the bottom surface, the rotatable cap being structured to engage with the top end of the cell body; and a ring member structured to couple with the bottom end of the cell body are provided.

A feed bag construction is provided comprising a feed bag, a first conduit sealed to the feed bag, a second conduit sealed to the interior of the feed bag for supplying wash reagent to the feed bag and a one piece cap that is removably mounted on the first conduit. The first conduit is provided with a hand operated butterfly valve to open or close the conduit.

A closure is described for a container containing a reagent. The closure includes a cover. The cover includes at least two through bore holes. The closure further includes a strip which includes a base and at least two septa. The base is of a stiff material and the septa is of a flexible material. The septa are attached to one surface of the base. Each septum includes a pre-slit bottom and a barrel forming the sides of the septum. The outer diameter of each septum barrel is larger than the inner diameter of the through bore hole such that a pressure is exerted on the septum when the septum is press fitted into the through bore hole.

In an example implementation, a reagent storage system for a microfluidic device includes a microfluidic chamber formed in a microfluidic device. A blister pack to store a reagent includes an electrically conductive membrane barrier adjacent to the chamber. A thinned region is formed in the membrane barrier, and a conductive trace is to supply electric current to heat and melt the thinned region. Melting the thinned region is to cause the membrane barrier to open and release the reagent into the chamber.