A connector for flexible tubing comprises a first hollow insert for allowing fluid flow, having a proximal end configured to fit inside the tubing, a first outer part, a joining member rigidly connecting the first insert to the outer part at a region spaced from the proximal end of the first insert and a generally annular gap between the first insert and the first outer part, which forms a tubing accepting opening at or adjacent the proximal end of the insert, the first outer part further comprising plural resilient protrusions extending into the gap, allowing the tubing to be inserted, but resisting removal of the tubing once inserted and wherein at least the insert, the joining member and the outer part are formed as a single integral molding.

A fluidic device can include: a plurality of fluid conduits, each fluid conduit including a first conduit portion separated from a second conduit portion; and at least one transport body that is movably positioned between the first conduit portion and the second conduit portion of each fluid conduit. The at least one transport body can include: at least one port adapted to be aligned with a first conduit portion and a second conduit portion of at least one first conduit so as to fluidly couple the first conduit portion with the second conduit portion; and at least one blocking body portion adapted to be aligned with a first conduit portion and a second conduit portion of at least one second conduit so as to fluidly isolate the first conduit portion from the second conduit portion of the at least one second conduit.

An assay system and method for use in the field of chemical testing is disclosed. The assay system can be used for filtering whole blood for testing on an integrated circuit containing digital control functionality.

A specimen container that includes a first cylindrical housing section having a first threaded end, a second threaded end, and a body section formed therebetween, wherein a fill line is placed at a predetermined location on the body section; a threaded winged section that is adapted to be attached to the second threaded end of the first cylindrical housing section, wherein the threaded winged section includes two gripping wings formed on opposite sides of the threaded winged section; a second cylindrical housing section having a first threaded end, a second threaded end, and a body section formed therebetween, wherein two gripping wings are formed on opposite sides of the second cylindrical housing section and are integral therewith; a threaded connector ring that is adapted to connect the first cylindrical housing section to the second cylindrical housing section; and at least one syringe plunger adapted for insertion into the first cylindrical housing section or the second cylindrical housing section.

A configurable device (10) for the flexible provision of connections and/or functions in a biopharmaceutical process comprises a body (20) in which predefined pipe sections (22) and plug-in locations (24) are formed by recesses in the material of the body (20). The configurable device (10) further comprises a plurality of functional elements (26) which are adapted to be inserted into the plug-in locations (24).

A device and method are provided to facilitate the handling of a volume of fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for receiving the volume of fluid. A stanchion has a first end received within the reservoir of the tube and a second end projecting from the open end of the elongated tube. In operation, the elongated tube is deposited in a first capsule having fluid therein. The first capsule is centrifuged such that the volume of fluid is received in a reservoir in the tube through the open end. The tube is removed from the first capsule and positioned in a second capsule such that the open end of the tube is spaced from a closed end of the second capsule. The second capsule is centrifuged such that the volume of fluid is expelled from the reservoir of the tube.

The present invention involves a reinforced tubing structure that is particularly useful for reinforcing tubing that is present inside disposable bioreactor bags, including for example thermowell tubing.

An insert for a liquid-holding container may include a body comprising a wall, an open top end and a bottom end, and a generally tubular lumen extending from the open top end to the open bottom end. The insert may include a plurality of first openings formed in the wall, the first openings being situated between the top and bottom ends, wherein each of the plurality of first openings defines an area, and wherein the plurality of first openings have substantially the same dimensions. The insert may include one or more second openings formed in the wall, the one or more second openings being situated between the top and bottom ends, wherein each of the one or more second openings defines an area that is greater than the area defined by any of the first openings, wherein the one or more second openings have substantially the same dimensions.

A method for ensuring a microbiological purity of a single-use device for carrying out a biotechnological process, the single-use device including at least one gamma-sterilizable component which is formed from materials suitable for a sterilization by gamma radiation, and at least one non-gamma-sterilizable subunit which contains a material unsuitable for a sterilization by gamma radiation. Both the component and the subunit each have an area that comes into contact with a process medium when the biotechnological process is carried out. The method includes the steps of sterilizing the gamma-sterilizable component by gamma radiation; protecting the medium-contacting area of the gamma-sterilizable component by a sterile barrier; sterilizing the non-gamma-sterilizable subunit with superheated steam; protecting the medium-contacting area of the non-gamma-sterilizable subunit by a sterile barrier; removing the sterile barriers; and mounting the gamma-sterilized component and the superheated steam-sterilized subunit in the single-use device immediately after removing the sterile barriers.

A system for passive permeation of a biological material is disclosed. The system may include a main channel extending between an upper portion and a lower portion; a main reservoir connected to the upper portion of the main channel and in fluid communication with the main channel; a bottom reservoir connected to the lower portion of the main channel and in fluid communication with the main channel; at least one secondary channel disposed in at least one position between the upper portion and the lower portion of the main channel such that fluid communication is established in the at least one position between the at least one secondary channel and the main channel; and at least one secondary reservoir respectively connected to an upper portion of each of the at least one secondary channel and in fluid communication with the respective at least one secondary channel.