A sampling device comprises a handle and a collector. The collector is connected to the handle. The collector has a capillary function and is able to automatically suction a liquid reagent or sample. The sampling device is able to suction a required amount of the reagent or sample quickly, conveniently and quantitatively. The sampling device can be product conveniently, and may achieve micro-quantitative sampling. The reagent is stored in the collector of the sampling device in the form of a dry powder, which may achieve the individual packaging of the detection reagent.

Provided is a technique for moving all of a droplet from a microchannel in which the droplet have been introduced to another layer.

The droplet transport device of the present disclosure includes a substrate having a through-hole or a recess, a first electrode provided on the substrate along the surface of the substrate and arranged at a position adjacent to the through-hole or the recess, a plurality of second electrodes provided on the substrate along a surface of the substrate and to which a voltage for moving the droplet introduced on the substrate is applied, and a dielectric layer covering the surface of the substrate, the first electrode, and the second electrodes, and a water-repellent film provided on the inner wall surface of the through-hole or the recess, and on the dielectric layer.

A thermal cycling method and associated device is described. The method is for carrying out a polymerase chain reaction (PCR) process to amplify deoxyribonucleic acid (DNA), and the method includes: pre-heating a series of blocks to respective temperatures that correspond to different respective heating stages in a PCR process, in which each block of the series of blocks defines a respective heat transfer surface, in which the series of blocks define a sequence of positions along a path, with each position defined by a respective heat transfer surface of a respective block; and moving a PCR reaction vessel, which contains deoxyribonucleic acid (DNA) and PCR reagents, along the path into and out of each respective position in the sequence of positions according to a schedule, in which, at each respective position the PCR reaction vessel is in thermal contact with the respective heat transfer surface to equilibrate a temperature of the PCR reaction vessel to a target temperature that corresponds to a respective heating stage in the PCR process.

The present invention provides a biological sample holder and handler system for cell-based liquid biopsies. The system is useful for performing diagnostic assays, based on a simple blood sample. For example, the system is useful for delivering precision cancer diagnoses that improve patient outcomes by optimizing treatment options, monitoring therapy efficacy, characterizing metastasis and assessing treatment toxicity

The invention relates to a sample acquiring device holder (3) for a housing (2) of an analysis apparatus (1). The sample acquiring device holder (3) may comprise an activating element (5) and a reception recess (11) for receiving a sample acquiring device (4). A first portion (10) of the activating element (5) may protrude into the reception recess (11), if the activating element (5) is in a non-activating position. The activating element (5) may be adapted to be moved into an activating position by the sample acquiring device (4), if the sample acquiring device (4) is inserted into an intended measurement position within the reception recess (11). The activating element (5) may be adapted to activate a measurement triggering element (15), if the activating element (5) is in its activating position, such that the measurement triggering element (15) activates a measurement of the analysis apparatus (1).

Flow cell devices, cartridges, and systems are described that provide reduced manufacturing complexity, lowered consumable costs, and flexible system throughput for nucleic acid sequencing and other chemical or biological analysis applications. The flow cell device can include a capillary flow cell device or a microfluidic flow cell device.

An aliquoting and freezing storage device comprises a test tube and at least one capillary tube. The capillary tube is inserted into a test tube, and the capillary tube is provided with an inner long hole which penetrates throughly. The device utilizes the capillarity to quickly and easily store biological samples in the capillary tubes. When needed, the operator only needs to remove one or several of the tubes, without affecting the remaining biological samples, so as to avoid repeated freezing and thawing of biological samples.

Method and apparatus for thermal processing of nucleic acid in a thermal profile is provided. The method employs at least a first bath and a second bath, the method further employing a reactor holder for holding reactor(s) accommodating reaction material containing the nucleic acid. The method comprises maintaining bath mediums in the baths at two different temperatures; and alternately allowing the reactor(s) to be in the two baths in a plurality of thermal cycles to alternately attain a predetermined high target temperature THT, and a predetermined low target temperature TLT, wherein the bath medium in at least one of the baths is a high thermal conductivity powder.

A method and device for analyzing a hematologic sample centrifuged within a capillary tube is provided. The device includes a tube holder, a sample imaging device, a processor, and a sample data display. The sample imaging device is operable to create a digital image of the sample within a region of the tube. The region is defined by substantially all of the radial width and axial length of the sample residing within the internal cavity of the tube in the region where the float resides after centrifugation. The sample imaging device is operable to produce signals representative of the image. The processor is adapted to produce information relating to bands of interest within the image based on the signals from the sample imaging device. The sample data display is adapted to display the results therefrom and/or a digital image of the sample within the region.

The invention relates to a method for tempering a plurality of capillaries, which are arranged on a carrier, wherein the carrier having a length, width and height receives the capillaries along the width of the carrier. The carrier has a recess in order to receive a tempering element so that the capillaries may be tempered in their central region by means of contact with the tempering element. According to the invention, the ends of the capillaries filled with samples are unsealed during tempering.