An apparatus suitable for handling biological material, for directly introducing or removing material to, or from, a container, comprising a body comprising at least one resealable port; a cover comprising an aperture and wherein the cover is disposed over an upper side of the body, and wherein the cover is moveable such that an aperture of the cover is configured to expose at least part of the resealable port.

A pipette tip system for use with a plurality of pipette tips is disclosed that includes a support card and a support card lid. The support card includes an array of pipette tip receiver openings arranged in a N×M array, wherein the N is less than M. The support card further has a short-side card rail edge on an edge of the support card along the N side of the array, and a long-side card rail edge on an edge of the support card along the M side of the array. The support card lid includes a long-side lid rail edge extending from a support card first surface, which is adapted to slidably mate with the long-side card rail edge, and a short-side lid rail edge extending from a support card second surface, which is adapted to slidably mate with the short-side card rail edge.

Provided are a gene detection kit and a gene detection device. The gene detection kit includes a kit body, a piston cylinder, and a piston. The kit body has an accommodating cavity and a plurality of reagent cavities. The piston cylinder is provided in the accommodating cavity, and the piston cylinder has a piston cavity. The piston is movably provided in the piston cavity along an axial direction of the piston cylinder. A first channel in communication with the piston cavity is provided on an outer circumferential surface of the piston cylinder, a plurality of second channels are provided on an inner wall of the accommodating cavity, each of the second channels is in corresponding communication with one of the reagent cavities, and the piston cylinder can move relative to the kit body, so that the plurality of second channels are alternately in communication with the first channel.

A biological analysis system for performing a performing an assay or experiment includes one or more of a carrier, base, or tray. The carrier, base, or tray is/are configured to interchangeably receive (1) a first block and a corresponding first cover placed over the first block or (2) a second block and a corresponding second cover placed over the second block; The system also includes a computer readable memory comprising instructions for detecting when the second cover is placed over the first block and/or for detecting when the first cover is placed over the second block based on lack of electrical continuity along an electrical path comprising one of the blocks and one of the covers.

The present invention provides a work hood that allows for free rotation in a work box to provide a wide work area and easy decontamination of a sealing portion present at the boundary between the work hood and the work box. A rotation support for rotatably supporting the entire half suit is provided. The rotation support includes a base portion, a rotating portion, a bearing portion, a sealing member, and a communication hole. The base portion is airtightly and annularly provided around an opening, and the rotating portion is provided around the base portion through the bearing portion, with a hem portion of the half suit being fixed to the rotating portion. The sealing member is annularly provided in an annular space formed by the base portion and the rotating portion so as to separate the work box and the external environment. The communication hole is provided so as to lead to the external environmental side from the annular small space side formed by the sealing member together with the base portion, the rotating portion, and the bearing portion, and is connected to a supply means for supplying a decontamination gas and the like to the inside of the small space and to a suction means for sucking clean air and the like from the inside of the small space.

A device and associated method for centrifuging a physiological fluid includes a container including a tip, a base, and a barrel extending between the tip and the base to hold a physiological fluid. The container includes a plunger positioned within the barrel of the container. The plunger includes a concave collection surface that faces the tip of the container. A plunger gasket seal is in sealing engagement with an inside wall of the barrel of the container. A bottom support is provided to support the base of the container at least partially within the bottom support for use in a centrifuge. The container is coupled to the bottom support using an interference fit. The collection surface of the plunger and at least the barrel can be made of the same material. Advantageously, the device can be used to process blood without the need for any added anticoagulant in the blood.

The present disclosure provides methods of preparing a biological specimen for imaging analysis, comprising fixing and clearing the biological specimen and subsequently analyzing the cleared biological specimen using microscopy. Also included are methods of quantifying cells, for example, active populations of cells in response to a stimulant. The present disclosure also provides devices for practicing the described methods. A flow-assisted clearing device provides rapid clearing of hydrogel-embedded biological specimens without the need of specialized equipment such as electrophoresis or perfusion devices.

The invention relates to a device for sealed transfer between two enclosed volumes, comprising a first flange and a second flange (10) which define a passage opening into the enclosed volumes and can be secured to each other by a first bayonet connection, a first door and a second door (11) which close off the passage openings and can be secured to each other by a second bayonet connection, the first door (11) being hingedly mounted on the first flange (10) by means of a hinge (4) comprising a hinge pin, characterized in that the device comprises an external manual control lever (9) which is secured to a rotary pin penetrating the first flange (10) and which is coupled to the hinge pin in such a way that the actuation of the control lever (9) drives the hinge pin, thus opening or closing the first door (11).

The invention relates to a device comprising: a support tray (7) for tubes receiving samples to be analyzed, this tray (7) having holes (8) adapted to each receive a tube bearing on the upper surface and with its bottom protruding from the tray; a lid (10) provided with chimneys (11) arranged according to a distribution similar to the distribution of the holes of the tray, this lid (10) being designed to occupy at least one position of superposition above the tray (7), so that the lid can be removably assembled to the tray to form a unitary assembly for holding the tubes and to position the chimneys (11) above the tubes in order to guide the pipette tips penetrating inside the tubes.

A reagent dispenser includes a housing. A container of microbial inhibitor is disposed within the housing. A dispensing system is disposed within the housing and operable to dispense the microbial inhibitor from the container. The dispensing system is calibrated to dispense a calibrated weight per water sample of the microbial inhibitor, such that a ratio of the calibrated weight per water sample to inner volume of a sample bottle substantially equals a predetermined concentration of microbial inhibitor per liter of water determined to acidify water to a pH of 4 or less.