Contamination detection systems, kits, and techniques are described for testing surfaces for the presence of hazardous contaminants, while minimizing user exposure to these contaminants. Even trace amounts of contaminants can be detected. A collection kit provides a swab that is simple to use, easy to hold and grip, allows the user to swab large areas of a surface, and keeps the user's hands away from the surface being tested. The kit also provides open and closed fluid transfer mechanism to transfer the collected fluid to a detection device while minimizing user exposure to hazardous contaminants in the collected fluid. Contamination detection kits can rapidly collect and detect hazardous drugs, including trace amounts of antineoplastic agents, in healthcare settings at the site of contamination.

Instrument for performing a diagnostic test on a fluidic cartridge A cartridge reader is for carrying out a diagnostic test on a sample contained in a fluidic cartridge inserted into the reader. The fluidic cartridge comprises a fluidic layer comprising at least one sample processing region, at least one collapsible blister containing a liquid reagent, a pneumatic interface, an electrical interface and at least one mechanical valve. The reader comprises a housing; an upper clamp occupying a fixed position relative to the reader, and a lower clamp, movable relative to the first clamp, wherein the upper clamp and the lower clamp define a cartridge receiving region therebetween. The reader comprises a thermal module comprised in the lower clamp, wherein the thermal module comprises at least one thermal stack for heating the at least one sample processing region of the cartridge inserted into the reader. The reader comprises at least one mechanical actuator for actuating the mechanical valve comprised in the cartridge inserted into the reader.

Modular active surface devices for microfluidic systems and methods of making same is disclosed. In one example, the modular active surface device includes an active surface layer mounted atop an active surface substrate, a mask mounted atop the active surface layer wherein the mask defines the area, height, and volume of the reaction chamber, and a substrate mounted atop the mask wherein the substrate provides the facing surface to the active surface layer. In other examples, both facing surfaces of the reaction chamber include active surface layers. Further, the modular active surface device can include other layers, such as, but not limited to, adhesive layers, stiffening layers for facilitating handling, and peel-off sealing layers. Further, a large-scale manufacturing method is provided of mass-producing the modular active surface devices. Further, a method is provided of using a plasma bonding process to bond the active surface layer to the active surface substrate.

Spectrophotometric measurements on highly absorbing turbid samples face technical challenges that can be solved by reducing a path length of an optical chamber used during measurement. Reducing the path length requires exceptional control of variables that may be difficult to achieve in unit-use and inexpensive cuvettes. The invention provides a precise inexpensive method for producing an optical cavity useful in making spectrophotometric measurements on high attenuation liquid samples. Two components are shaped such that, when in contact, a central optical chamber and peripheral groove are formed. Liquid adhesive dispensed into the groove wicks around the interface perimeter, sealing the components together when cured. This results in a short precisely controlled path length that reduces chances of mechanical induced distortions (that arise with other bonding methods). The invention provides for manufacturing of a consistent optical chamber with very short path length within a diagnostic cartridge or cuvette.

An all-in-one self test kit includes: a test tool having a reagent container adapted to store a diagnosis reagent therein and a diagnosis kit with a casing constituted of a first body and a second body and a diagnosis strip disposed inside the casing and having a sucking part for sucking the diagnosis reagent and a diagnosis part reacting to the diagnosis reagent sucked to the sucking part; a sub-body having a container insertion portion for inserting the reagent container thereinto and a kit insertion portion for inserting the diagnosis kit thereinto; a main body for inserting the sub-body thereinto; and a cap fastened and unfastened with an entrance of the main body to open and close the main body.

A female urinary diagnostic device including a urine stream collection container having a discharge opening and a stream collection opening, the stream collection opening being configured to surround and isolate a urethral opening, a probe guide passage configured for interior engagement with a vaginal opening for placement of the stream collection opening relative to the urethral opening, and an internal baffle that defines an interior wall of the urine stream collection container that provides a spillway from the stream collection opening to the discharge opening and cooperates with at least a urine sensing device, where the spillway provides urine passage to the urine sensing device and a collection tank, wherein the internal baffle forms at least a portion of the probe guide passage and defines a sounding probe guide surface that positions a sounding probe within the vaginal opening.

Broadly speaking, embodiments of the present techniques provide a liquid handling device that enables a user to more easily and efficiently perform sample dilutions, without requiring the user to perform any calculations or be in a controlled environment (e.g. a laboratory or sterile/aseptic environment). Advantageously, this may enable a user to perform sample dilutions and subsequent sample processing outside of a laboratory, such as during field work, or in environments, regions or countries where access to sterile/aseptic environments may be difficult or nonexistent. The device may be used to dilute any liquid sample, such as biological samples, chemical samples, or environmental samples (e.g. liquid samples taken from a river or lake, or soil samples that are mixed with liquid).

An example device with a microfluidic channel for use in a chamber is provided, the example device comprising: a chamber to contain a fluid; a microfluidic channel located internal to the chamber, the microfluidic channel having an entrance within the chamber and an exit within the chamber, the microfluidic channel defined by a housing located within the chamber; a unidirectional displacement mechanism inside the microfluidic channel, the unidirectional displacement mechanism located between the entrance and the exit; and a controller to activate the unidirectional displacement mechanism to cause the fluid from the chamber to enter the microfluidic channel via the entrance and leave the microfluidic channel via the exit thereby agitating the fluid within the chamber, the fluid otherwise being non-moving.

The present embodiments relate to a fluid control device using centrifugal force. The fluid control device using centrifugal force includes a fluid control portion comprising a plurality of chambers and controlling a movement of a fluid inside the chamber; a lower fixing portion positioned on a lower portion of the fluid control portion and fixing the plurality of chambers; an upper fixing portion positioned an on upper portion of the fluid control portion and fixing the plurality of chambers; and a fastening member penetrating and fastening the lower fixing portion, the fluid control portion, and the upper fixing portion, wherein the plurality of chambers are disposed to face each other and placed on the lower fixing portion.

A media holder can be used for preparing samples. The media holder can comprise a base, a pair of walls extending upwardly from the base, and a plurality of transverse members positioned on and coupled to a respective upper end of each of the walls. Each of the transverse members can define a receiving slot for receiving at least a portion of a media therein.