The present invention provides a substrate analysis nozzle that reliably prevents a leakage (release) of analysis solution from the nozzle even in the case of a highly hydrophilic substrate and that collects the analysis solution with a high collection ratio after scanning. The present invention is directed to a substrate analysis nozzle configured to discharge an analysis solution from a tip of the substrate analysis nozzle onto a substrate, configured to scan a surface of the substrate using the discharged analysis solution, and configured to suck the analysis solution. The substrate analysis nozzle has a triple-tube structure made up of: a pipe through which the analysis solution is discharged and sucked; a first outer tube surrounding the pipe and surrounding the analysis solution used for scanning; and a second outer tube surrounding the first outer tube. The substrate analysis nozzle includes: first exhausting means including an exhaust path defined between the pipe and the first outer tube; and second exhausting means including an exhaust path defined between the first outer tube and the second outer tube.

The present invention relates to a separable cassette for measuring glycated hemoglobin. It is easy to use the separable cassette for measuring glycated hemoglobin of the present invention since a reagent is sequentially leaked during the rotation thereof. In addition, there is no need to shake the reagent beforehand, as the reagent without residual reagent is fully discharged by the rotation. Therefore, the measurement result is accurate because an error between the amount of the reagent used and the amount of sample blood is small.

Systems and methods for delivering fluid to a microfluidic device is provided. The system includes a multi-well plate having a plurality of wells and an inlet tube having a first end being in communication with the one or more wells of the multi-well plate and a second end being in communication with a microfluidic device. The first end of the inlet tube is moveable between the plurality of wells of the multi-well plate to deliver fluid to the microfluidic device from the plurality of wells of the multi-well plate.

A dispensing method executed in a robot system including a pipette, a tip, a container, a liquid in the container, and a robot including a robot arm, an end effector, and a robot controller that controls the robot arm and the end effector to perform operations on the pipette and the tip, includes: making the end effector hold the pipette and the tip attached to the pipette; dipping at least a point of the tip attached to the pipette in the liquid and aspirating the liquid into the tip; bringing an outer surface of the tip attached to the pipette into contact with a part of the container, wherein the part of the container is at least one of an edge of an opening and an inside surface; and pulling the pipette and the tip attached to the pipette out of the container through the opening.

The present invention relates to a recovery assembly for a cooling agent in a cryopreservation device, the recovery assembly comprises a cone-shaped funnel assembly comprising a support for mounting the funnel assembly to an access opening of a container to be at least partially filled with a cooling agent.

The invention relates to the preparation of samples on mass spectrometric sample supports with dispensing of liquids, and particularly to devices and methods to clean the dispenser. During dispensing of hundreds of samples, solved material may crystallize over time as deposit at the capillary tip of the dispenser, which impedes the vertical detachment of the drop in the medium and long run. Therefore, frequently cleaning the capillary tip is essential for a robust operation of the preparation device. The invention proposes to automatically clean the dispenser tip by creating a drop of washing fluid, such as pure solvent, fully enclosing the dispenser tip. The washing fluid is fed through a channel outside the central dispenser capillary to a location slightly above the capillary tip. The size of the hanging drop of washing fluid is photometrically regulated and monitored to prevent it from falling off prematurely.

An adapter for clinical, medical and laboratory equipment containers comprises: (a) a cylindrical substrate wherein the substrate comprises a plurality of ribs that extend outwardly from the substrate to orient and hold the adapter in an opening of the container and (b) an elastomeric insert that is formed or inserted into an opening in the substrate wherein the elastomeric insert comprises: (i) a transfer instrument passageway that allows a tip of a transfer implement to pass through the elastomeric insert and allow a liquid contained in the container to be drawn into the transfer implement and (ii) an air passage structure to allow air to be drawn into the container when the liquid is being drawn into the transfer implement.

Fraction collector dispensers and methods of using such dispensers are provided. In one embodiment, the dispenser includes an inlet for receiving liquid from a liquid source, wherein the inlet is in fluid communication with an outlet from which liquid is dispensed into a receptacle; and a reservoir in fluid communication with a flow path between the inlet and outlet, wherein the reservoir comprises trapped air therein and is configured to receive liquid during movement of the dispenser between receptacles or during movement of receptacles between dispense positions, wherein the dispenser is moveable between a first receptacle and a second receptacle or the receptacles are moveable between dispense positions.

The invention relates to the preparation of samples on mass spectrometric sample supports with dispensing of liquids, and particularly to devices and methods to clean the dispenser. During dispensing of hundreds of samples, solved material may crystallize over time as deposit at the capillary tip of the dispenser, which impedes the vertical detachment of the drop in the medium and long run. Therefore, frequently cleaning the capillary tip is essential for a robust operation of the preparation device. The invention proposes to automatically clean the dispenser tip by creating a drop of washing fluid, such as pure solvent, fully enclosing the dispenser tip. The washing fluid is fed through a channel outside the central dispenser capillary to a location slightly above the capillary tip. The size of the hanging drop of washing fluid is photometrically regulated and monitored to prevent it from falling off prematurely.

The present disclosure, in some aspects, provides sample collection devices useful for collection of a sample such as by a human. In other aspects, the present disclosure is directed to kits comprising the sample collection devices described herein, and components thereof, and methods of using the sample collection devices described herein.