A specimen cap. The specimen cap allows material to be transferred out of a specimen cup without exposing the user (clinician, lab tech, phlebotomist) to the sample. The cap employs a double cap system with a secondary cap providing access to a needle holder that holds a needle assembly. The needle assembly has an upward extending needle, with an optional needle cover, and a downward extending draw or sample tube extending downward to reach the sample contained in the specimen cup.

A specimen cap. The specimen cap allows material to be transferred out of a specimen cup without exposing the user (clinician, lab tech, phlebotomist) to the sample. The cap employs a double cap system with a secondary cap providing access to a needle holder that holds a needle assembly. The needle assembly has an upward extending needle, with an optional needle cover, and a downward extending draw or sample tube extending downward to reach the sample contained in the specimen cup.

The disclosure relates to devices, solutions and methods for collecting and processing samples of bodily fluids containing cells (as well as embodiments for the collection, and processing and/or analysis of other fluids including toxic and/or hazardous substances/fluids). In addition, the disclosure relates generally to function genomic studies and to the isolation and preservation of cells from saliva and other bodily fluids (e.g., urine), for cellular analysis. With respect to devices for collection of bodily fluids, some embodiments include two mating bodies, a cap and a tube (for example), where, in some embodiments, the cap includes a closed interior space for holding a sample preservative solution and mates with the tube to constitute the (closed) sample collection device. Upon mating, the preservation solution flows into the closed interior space to preserve cells in the bodily fluid. The tube is configured to receive a donor sample of bodily fluid (e.g., saliva, urine), which can then be subjected to processing to extract a plurality of cells. The plurality of cells can be further processed to isolate one and/or another cell type therefrom. The plurality of cells, as well as the isolated cell type(s), can be analyzed for functional genomic and epigenetic studies, as well as biomarker discovery.

Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods that may be used to safely manually add or remove fluid within a cartridge while it is actively applying DMF. Also described herein are DMF readers for use with a DMF cartridges, including those including multiple and/or redundant safety interlocks. Also described herein are DMF reader devices having a cover with active control of microfluidics on the cover while actively controlling DMF on the reader base.

An apparatus for collecting and testing a sample is provided. The apparatus includes a test cavity and a collecting component. The test cavity is connected to the collecting component and the test cavity and the collecting component are in a liquid communication. An inner wall of the test cavity is provided with a first step. The collecting component includes a collecting rod and an absorbing element sleeved on the collecting rod. A connecting end of the collecting rod is provided with a barb. A tail end of the barb is tapered. The barb at the connecting end is clamped to the first step to connect the test cavity with the collecting component. A collecting and testing apparatus with an integrated structure is provided. The integrated structure integrates the collection and test of a sample, reduces a product structure and an operation difficulty of subjects.

The disclosure relates to devices, solutions and methods for collecting and processing samples of bodily fluids containing cells (as well as embodiments for the collection, and processing and/or analysis of other fluids including toxic and/or hazardous substances/fluids). In addition, the disclosure relates generally to function genomic studies and to the isolation and preservation of cells from saliva and other bodily fluids (e.g., urine), for cellular analysis. With respect to devices for collection of bodily fluids, some embodiments include two mating bodies, a cap and a tube (for example), where, in some embodiments, the cap includes a closed interior space for holding a sample preservative solution and mates with the tube to constitute the (closed) sample collection device. Upon mating, the preservation solution flows into the closed interior space to preserve cells in the bodily fluid. The tube is configured to receive a donor sample of bodily fluid (e.g., saliva, urine), which can then be subjected to processing to extract a plurality of cells. The plurality of cells can be further processed to isolate one and/or another cell type therefrom. The plurality of cells, as well as the isolated cell type(s), can be analyzed for functional genomic and epigenetic studies, as well as biomarker discovery.

A cap closes a sample vessel for the microwave treatment of samples. The cap contains a closure body for closing the sample vessel. The closure body is fitted to the sample vessel and closes the sample vessel at a sealing surface. A spring-loaded pressure relief valve and a vent duct are provided. The vent duct, the pressure relief valve and the closure body are configured in such a manner that the vent duct connects the closure body via the pressure relief valve to the surrounding area such that when a defined first pressure level is exceeded at the closure body excess pressure can escape through the vent duct into the area surrounding the cap. A reservoir is provided. The reservoir and the vent duct are configured such that condensate precipitating in the vent duct accumulates in the reservoir when the cap is in the state fitted to the sample vessel.

Disclosed is a specimen treatment device for treating a specimen accommodated in a reaction container, the specimen treatment device comprising: an installation unit in which the reaction container is installed; a temperature adjusting unit for warming the reaction container installed in the installation unit; and an opening/closing member which can move between a first position at which the temperature adjusting unit is uncovered and a second position at which the temperature adjusting unit is covered.

A point of care cassette, comprising: a housing; a lancet carrier for carrying a lancet, the lancet carrier being configured to be retractably urged by a spring from a locked position to a deployed position in response to an actuation of a first trigger, the lancet being entirely within the housing when not in the deployed position; and a test carrier for carrying a testing medium, the test carrier configured to be urged by a second spring from a locked position to a deployed position in response to an actuation of a second trigger, the second trigger being actuated during deployment of the lancet carrier to bring the testing medium proximate a blood sample after retraction of the lancet.

A laboratory sample vessel distribution system is presented. The system comprises a cabinet, sample vessel carriers for receiving sample vessels, and a cabinet drawer for receiving a sample vessel carrier. The drawer is locatable in different positions: closed, opened, and fully opened. An actuator moves the sample vessels and the sample vessel carriers between different locations. An actuator driver drives the actuator and applies a first mode of operation with a first speed and a second mode of operation with a second reduced speed compared to the first speed. A sensor device detects between opened and closed positions and provides position signals. A control device is connected to the actuator driver and the sensor device. The control device provides control signals to the actuator driver instructing the actuator driver to apply either the first mode, if in the closed position, or the second mode, if in the opened position.