A lab-on-chip type system, capable of identifying antibiotic sensitivity at the point of care of patients, especially in rural areas, clinics, hospitals that do not have care 24/7, hospitals with low level of equipment, among others, from the extraction of a sample, comprising a micro device or medical base device and a dispenser, wherein said micro device comprises a plurality of microwells, arranged in a circular fashion on one of the faces of the micro device, and wherein the micro-dispenser comprises a central plunger for taking and supplying the sample, a chamber for storage and distribution of the sample and a plurality of microdispensers arranged in a circular manner through which the sample is introduced into the microwells of the micro device.

A microfluidic diagnostic chip may comprise a microfluidic channel, a functionalizable enzymatic sensor in the microfluidic channel, the functionalizable enzymatic sensor comprising a binding surface to bind with a biomarker in a fluid, and a microfluidic pump to pass the fluid over the binding surface. A microfluidic device may comprise a number of pumps to pump a fluid though the number of microfluidic channels and a number of microfluidic channels comprising at least one sensor to detect a change in a chemical characteristic of the fluid in response to presence of the fluid on the sensor

A method and a system for controlled usage of a laboratory glassware 123 comprises defining the usage control of the laboratory glassware 123, at a remote server 130, by receiving a first information from a computing device 120, and thereby generating a virtual stamp associated with the laboratory glassware 123. The first information is received over a communication link 160 from the computing device 120 by scanning a QR code associated with the glassware 123 using a scanning module 210 of the computing device 120. The remote server 130 allows an authorized user to define the usage control information in the virtual stamp for the controlled usage of the glassware 123.

Vial assemblies comprise a tubular body and a cap, the cap including a first portion configured to abut a lip of an open end of the tubular body, a threaded portion configured to couple to threading on an internal surface of the tubular body, and a second portion protruding from the threaded portion and extending into a cavity of the tubular body. Methods for storing and removing frozen samples from such vial assemblies are also described.

A tight connection device for the aseptic transfer of a biopharmaceutical product includes: a stationary temporary clamping means keeping the container hermetically clamped against the chamber; a stationary unlocking means capable of switching the container from an initial locked position to an intermediate unlocked position; a stationary locking means; and an annular functional crown capable of being rotated to actuate the stationary unlocking means and the stationary locking means of the container. The stationary unlocking means and the stationary locking means are mechanically linked to the annular functional crown and arranged such that the rotation of the annular functional crown and the end locked position. The device further includes stationary immobilising/release means capable of allowing and preventing the annular functional crown to rotate.

The present disclosure is drawn to inertial pumps. An inertial pump can include a microfluidic channel, a fluid actuator located in the microfluidic channel, and a check valve located in the microfluidic channel. The check valve can include a moveable valve element, a narrowed channel segment located upstream of the moveable valve element, and a blocking element formed in the microfluidic channel downstream of the moveable valve element. The narrowed channel segment can have a width less than a width of the moveable valve element so that the moveable valve element can block fluid flow through the check valve when the moveable valve element is positioned in the narrowed channel segment. The blocking element can be configured such that the blocking element constrains the moveable valve element within the check valve while also allowing fluid flow when the moveable valve element is positioned against the blocking element.

A method for determining a numerical score representative of a patient's health, is characterized by the following steps. At an initial calibration step, a database is established from a series of indicators relating to the state of health of the patient, each indicator being assigned a numerical value, and afterwards a statistical analysis of this database is performed so as to establish for each of said indicators a score depending on a measured value of the indicators of the state of health with respect to reference values, and to establish at least four groups constituted by said indicators, each of said groups representing information corresponding respectively to oxidative stress, hereinafter Group 1; to functions of the digestive brain, hereinafter Group 2; to functions of the reptilian brain, hereinafter Group 3; and to physical abilities of the patient coupled to his information on his general state of health, hereinafter Group 4. Furthermore, a value is assigned to each group, then a health score S specific to the patient is calculated using the formula:

S=(Value Group 1+(2* Value Group 2)+(2* Value Group 3)+(3* Value Group 4))/(2* Number of groups)

Methods of transferring material from a first device having an array of microwells to a second device is provided. In some examples, the first device and the second device are moved together toward a stopper plate and impinge on the stopper plate. In other examples, the first device and the second device are kept stationary and an impinging device is impacted on a mounting structure enclosing the first and second devices, causing material transfer from the microwells of the first device to the second device. Apparatus for carrying out the transfer of material is also disclosed.

Provided herein are devices, kits, systems, and methods for collecting samples for analytical analysis and the safe disposal of sample collection devices after their use. The devices, kits, systems, and methods find use, for example, for disposing of biohazard materials by users in settings that may not be equipped with the professional biohazard disposal systems of laboratories, hospitals, and medical clinics.

A method for collecting and delivering biological samples to a destination, such as an analyzer are provided herein. In one example, a plurality of samples, each including particles, is obtained from respective wells of a sample source having a plurality of wells. The plurality of samples are introduced into a fluid flow stream contained within a conduit having an inner diameter and in communication with a destination. An inner surface of the conduit is coated with a hydrogel barrier substance, such as poly-HEMA. The fluid flow stream is guided through the conduit to a destination. In one example, the destination may be a flow cytometer. Methods of preparing a poly-HEMA solution and coating the inner surface of a conduit with poly-HEMA are also provided.