Provided herein are devices, methods, and systems for polynucleotide synthesis comprising a thermocycler comprising a plurality of individual reaction chambers having a capability to control its own temperature setting. The devices, methods, and systems provided herein further comprise a detection module and a light source that are used to monitor the progress of the polynucleotide synthesis reaction in the individual reaction chambers and the quality and quantity of the synthesized polynucleotides.

Systems, methods, and collection devices are disclosed for rapid, local PCR testing. The PCR testing system may be configured for use with a disposable sample collection device that includes a swab configured for collecting a biological sample from a patient; and a sample container configured to receive the swab and separate a bulk quantity of the biological sample from the swab for containment in a bulk collection chamber, which is located with the sample container, wherein the sample container is configured to meter a selected volume of the biological sample into a PCR sample tube, which contains a lyophilized master mix, releasably attachable to the sample container.

An apparatus for testing a fluid sample including a sample receiving member having an opening for receiving a fluid sample, wherein the sample receiving member comprises at least a first and second sample collection chambers, a sample retention member, in fluid communication with the first sample collection chamber, to retain a portion of the fluid sample, and at least one test strip, in fluid communication with the second collection chamber, to indicate the presence or absence of at least one analyte in the fluid sample, wherein the first collection chamber is not in fluid communication with the second collection chamber.

A sample analyzing method and a sample preparing method are provided. The sample analyzing method includes a sample preparing step, a placing step, and an analyzing step. The sample preparing step includes an obtaining step implemented by obtaining an identification information; and a marking and placing step implemented by placing a sample carrying component having a sample disposed thereon into a marking equipment, allowing the marking equipment to utilize the identification information to form an identification structure on the sample carrying component, and placing the sample carrying component into one of the accommodating slots according to the identification information. The placing step is implemented by taking out the sample carrying component from one of the accommodating slots and placing the sample carrying component into an electron microscope equipment. The analyzing step is implemented by utilizing the electron microscope equipment to photograph the sample to generate an analyzation image.

Devices and methods are provided that permit efficient and selective separation of liquid biological specimens into at least two constituent components to facilitate subsequent quantitative and qualitative analysis on at least one analyte of interest in at least one of the components. The devices generally include one or more sample deposition regions supported on a base. Each sample deposition region includes a separation membrane for separating the liquid biological specimen into two different fractions. The first fraction is trapped by the separation membrane while the second fraction passes through the separation membrane and into a respective collection membrane. The separation and collection membranes are easily separable from the devices and can be utilized for further processing and analysis.

The device for the storage and traceability of biological specimens placed in holders is provided with identification information in the form of encoded data. The device includes at least one tray provided with a plurality of cells for the storage of the holders provided with storage housings for the holders, at least one apparatus for reading encoded data and determining data relative to the location of each holder within the receptacle, and a computerized processor for the data read and determined by the apparatus. The is a device for recognizing an empty housing within the receptacle defined by a detector for a physical characteristic of the bottom of the cell or an element secured to this bottom.

A sampling kit for tissue including a reaction chamber and a sampling device configured for mounting in the reaction chamber and providing a reaction volume defined between the base of the reaction chamber and the sampling device. The sampling device has a proximal handling portion and a distal scraping portion comprising a scraping formation configured to collect a sample of tissue when the distal scraping portion is rubbed against a surface of the tissue. The sampling device comprises an internal lumen configured for the supply of reaction liquid from a distal end of the tissue sampling device to the reaction volume via a distal aperture disposed in the distal scraping portion when the tissue sampling device is mounted in the reaction chamber. An automated high-throughput sampling and indexing system is also described.

A stack of histology cassettes configured to be inserted into a hopper of a printer, wherein each histology cassette in the stack includes a bottom face, a top face opposite the bottom face, a front face, a rear face opposite the front face, a first lateral face and a second lateral face opposite the first lateral face. The top face of the histology cassette is open to allow a sample to be received within the histology cassette. The histology cassettes have substantially the same orientation within the stack. The histology cassettes in the stack are arranged with a first histology cassette at the bottom of a stack, and each subsequent histology cassette in the stack up to a last histology cassette in the stack is arranged with its bottom face positioned on the top face of a preceding histology cassette in the stack.

The equipment item for automatically managing a plurality of biological samples placed in a respective sample jar includes a storage container for sample jars having a plurality of housings, an apparatus with a reader of encoded identification data affixed on the sample jars placed in the container, a device for determining data representative of the position of each sample jar within the container, and a device for rotating the container, and a computer processor connected to the apparatus. The container includes, in the immediate vicinity of each housing, a shape appearing recessed or raised, while the device for determining data representative of the position of each sample jar is defined by a detector for the shape.

A detection device, the device comprising a sample liquid bearing device (300), test strips (200), a test strips bearing plate (100) and a signal acquisition positioning assisting device, wherein the sample liquid bearing device (300) comprises two or more samples cells (320) used for containing sample liquid, each of the test strips (200) at least comprises an identity information bearing part (250), a developing part (220) and a capillary part (210), the test strip bearing plate (100) is used for placing the test strips (200) in the same circular ring in a circumferential array radial manner, and the signal acquisition positioning assisting device is arranged on the test strip bearing plate and is used for positioning the test strips.