The embodiment of the present disclosure provides a temperature control device and a temperature control system. The temperature control device comprises an object stage, a housing, and at least one temperature control structure. The temperature control structure has a main body portion and a temperature control component, and main body portion defines an air duct, and wherein, the main body portion has a second air inlet and a second air outlet, and the first air inlet is connected to the second air outlet, and the external air enters the air duct defined by the main body portion from the second air inlet of the main body portion, and the air then enters the housing through the second air outlet, and the temperature control component is connected, so as to the main body portion to control the temperature of the air in the air duct.

Devices and methods for the detection of nucleic acids (e.g., RNA, DNA) are described. The nucleic acid can be obtained or derived from a pathogen, such as a virus. In one embodiment, the virus is a coronavirus (e.g., SARS-CoV-2) related to the disease COVID-19. Accordingly, devices and methods may be used in the field as point-of-care devices to test a subject (e.g., a patient) for the presence of the SARS-CoV-2 virus or another nucleic acid.

A sampling kit for tissue including a reaction chamber and a sampling device configured for mounting in the reaction chamber and providing a reaction volume defined between the base of the reaction chamber and the sampling device. The sampling device has a proximal handling portion and a distal scraping portion comprising a scraping formation configured to collect a sample of tissue when the distal scraping portion is rubbed against a surface of the tissue. The sampling device comprises an internal lumen configured for the supply of reaction liquid from a distal end of the tissue sampling device to the reaction volume via a distal aperture disposed in the distal scraping portion when the tissue sampling device is mounted in the reaction chamber. An automated high-throughput sampling and indexing system is also described.

A system for analyzing a physiological sample includes a cartridge configured to attach to the skin of a subject. The cartridge includes: a processing fluid pack that is configured to release a processing fluid stored therein, a diagnostic test strip, and a vacuum pin. The system also includes a lancet with a needle. The lancet is configured to deploy the needle upon engagement with the cartridge to draw a physiological sample from the subject. The vacuum pin is configured to create a vacuum within the cartridge to draw the released processing fluid and the drawn physiological sample to the diagnostic test strip.

The invention concerns a method, an assembly and a system for determining a characteristic property of a molecular interaction. The method includes providing a liquid sample including a particle capable of being in a state of equilibrium and in a state of non-equilibrium. The particle includes a marker in at least one of its state of equilibrium and state of non-equilibrium. The method further includes bringing the particle in a state of non-equilibrium by subjecting the sample to a condition jump comprising a jump in temperature and/or pressure; reading out the marker as a function of time during at least a portion of a relaxation time for said particle, and determining said characteristic property of said molecular interaction.

A system and method of monitoring sobriety using a hand-held breath testing device that, on receipt of a user's breath, generates a breath test signal comprising substance content data and user identification data, and wirelessly transmits the breath test signal to a breath test signal receiving station.

A microfluidic diagnostic chip may comprise a microfluidic channel, a functionalizable enzymatic sensor in the microfluidic channel, the functionalizable enzymatic sensor comprising a binding surface to bind with a biomarker in a fluid, and a microfluidic pump to pass the fluid over the binding surface. A microfluidic device may comprise a number of pumps to pump a fluid though the number of microfluidic channels and a number of microfluidic channels comprising at least one sensor to detect a change in a chemical characteristic of the fluid in response to presence of the fluid on the sensor

Automation compatible removable lids are provided. The removable lids include a top surface surrounded by a peripheral rim. The removable lids further include septal portions configured to receive an extractor, such as a pipette tip, inserted therethrough. The septal portions are further configured to grip the extractor to facilitate lid removal.

The present disclosure provides a digital microfluidic (DMF) cartridge for performing a self-test for a target analyte, including a DMF cartridge comprising a bottom substrate and a top substrate separated by a droplet operations gap, wherein the bottom substrate comprises a plurality of droplet operations electrodes configured for performing droplet operations on a liquid droplet in the droplet operations gap; one or more reaction chambers or reaction zones on the bottom substrate that are supplied by an arrangement of the droplet operations electrodes, wherein each reaction chamber or reaction zone comprises at least one detection spot and is configured for performing a plasmonic particle-assisted ELISA (pELISA) for detection and quantification of a target analyte in a sample droplet. The device may include downloadable software for a self-test and be operable using a smart device.

A method and a system for controlled usage of a laboratory glassware 123 comprises defining the usage control of the laboratory glassware 123, at a remote server 130, by receiving a first information from a computing device 120, and thereby generating a virtual stamp associated with the laboratory glassware 123. The first information is received over a communication link 160 from the computing device 120 by scanning a QR code associated with the glassware 123 using a scanning module 210 of the computing device 120. The remote server 130 allows an authorized user to define the usage control information in the virtual stamp for the controlled usage of the glassware 123.