A diagnostic and treatment assembly, configured to diagnose and treat cellular disease. The diagnostic and treatment assembly has a radio wave generator communicatively coupled to a carrier modulator and a radio wave amplifier. An impedance matching system is electrically coupled to the radio wave amplifier. A reflected wave sensor is electrically coupled to the impedance matching system. A radiator applicator is electrically coupled to the reflected wave sensor. A vector impedance analyzer is electrically coupled to the radio wave amplifier. An information collector data network is electrically coupled to the vector impedance analyzer. A data logger is communicatively coupled to the carrier modulator, the vector impedance analyzer, and the reflected wave sensor. The diagnostic and treatment assembly operates in a low-power mode to diagnose a cellular disease and in a high-power mode to treat the cellular disease.

Systems, computer program products, and methods for using a flow cell array are provided herein. A computer program product includes a computer readable storage medium having program instructions embodied therewith, the program instructions executable by a device to cause the device to deliver multiple items of chemical matter independently to multiple reaction sites of a flow cell array across multiple distinct instances of time; image multiple parallel chemical reactions at the multiple reaction sites of the flow cell array; and record an emission from each of the multiple chemical reactions site.

The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor.

A reaction vessel for a diagnostic analyzer comprising a plurality of processing stations. The reaction vessel comprises at least one sensor configured to measure at least one physical parameter associated with at least one of the processing stations of the diagnostic analyzer when disposed at the at least one of the processing stations, a memory configured to at least temporarily store at least one measurement value indicating the physical parameter provided by the sensor, a processing unit configured to control the sensor and to output measurement data including the measurement value from the memory, an interface configured to provide communication of the processing unit with an external electronic device, a power source configured to supply electric power to the sensor, the processing unit and the memory. The reaction vessel defines an internal volume. The sensor, the processing unit, the memory and the interface are arranged within the internal volume.

Described herein is novel, economical device for photodetection of presence of a target nucleic acid in a sample. Accordingly, the detection takes place based on difference in light intensities. The invention further describes the method and apparatus for detection of target nucleic acid using said device.

Techniques for antenna positioning system having a drive element shared by multiple antennas for positioning about a positioning degree of freedom are described. In some examples, each antenna can be coupled with a rotating spindle, with each antenna spindle being coupled with the shared drive element. By driving a shared drive element, each of the antenna spindles in the system can be rotated via the associated coupling. In some examples, such a coupling may include link arms with an adjustable length to reduce backlash or to apply a preload to the system. In some examples, such a coupling may be configured to position multiple antennas over different orientation ranges in response to the drive element driving over an actuation range, which may include one antenna being idled or otherwise maintained at an orientation while another antenna is driven, or may include different antennas being driven according to different actuation ratios.

A single-use test plate in a biological test system for determining the presence of one or more nucleic acid sequences, the test plate including a body having channels and sockets formed therein, an inlet for receiving a test sample, an air inlet, an extraction membrane, reaction zones containing a porous media with first and second reaction mixtures allowing amplification and detection of the nucleic acid species, an air outlet, a recovery reservoir, the plate being configured to feed the biological sample to be tested into the extraction membrane, then after rinsing, drying and elution of said extraction membrane, to feed the resulting eluate into the reaction zones, in order, after reaction, to deduce therefrom a result through the readout zone.

A diagnostic and treatment assembly, configured to diagnose and treat cellular disease. The diagnostic and treatment assembly has a radio wave generator communicatively coupled to a carrier modulator and a radio wave amplifier. An impedance matching system is electrically coupled to the radio wave amplifier. A reflected wave sensor is electrically coupled to the impedance matching system. A radiator applicator is electrically coupled to the reflected wave sensor. A vector impedance analyzer is electrically coupled to the radio wave amplifier. An information collector data network is electrically coupled to the vector impedance analyzer. A data logger is communicatively coupled to the carrier modulator, the vector impedance analyzer, and the reflected wave sensor. The diagnostic and treatment assembly operates in a low-power mode to diagnose a cellular disease and in a high-power mode to treat the cellular disease.

A fluidic handling unit includes a baseplate, a fluidic inlet block, a fluidic outlet block, a pump in fluidic communication with the fluidic inlet block and the fluidic outlet block, a carrier control board in electrical communication with the pump, and a flow cell carrier comprising a microfluidic flow cell receiving area, wherein the flow cell carrier is configured to receive and retain the fluidic handling unit. A bottom surface of the fluidic handling unit is configured to complementary mate with a top surface of the flow cell carrier, or wherein a bottom surface of the flow cell carrier is configured to complementarily mate with a top surface of the fluidic handling unit.