Patent classifications
B01L2300/025
Toilet with Digitally Controlled Manifold to Distribute Fluids
An analytical toilet comprising a bowl for receiving excreta from a user; a flush mechanism for cleaning the bowl after use; at least one analytical test device wherein a sample of excreta is analyzed; a manifold comprising conduits and valves for distributing one or more fluids to and from the at least one receptacle; and a digital control device controlling the valves to distribute the sample to the analytical test device for analysis; and distribute fluid to remove the sample from the analytical test device after analysis and to clean the analytical test device is disclosed.
Toilet with Microfluidic Chips for Testing Samples
An analytical toilet comprising a bowl adapted to receive excreta; one or more conduits for transporting a sample from the bowl; one or more fluid sources in fluid connection with the one or more conduits; and one or more microfluidic chips, comprising at least one fluid inlet; at least one fluid outlet; and a sensor configured to detect at least one property of an excreta sample is disclosed.
RETRACTABLE AND HYBRID DIAGNOSTIC TEST DEVICES, KITS AND METHODS
The present disclosure relates to retractable diagnostic devices, and hybrid diagnostic devices comprised of water-dispersible, flushable, biodegradable, or water-soluble material and non-water-dispersible, non-flushable, or non-water-soluble material.
Specimen tester including a separate initiator and method
A specimen collection, storage, transport, and testing device can include an outer vessel containing an internal cup having an openable drain having a brim raised above the bottom floor of the cup. Once opened the drain allows a portion of liquid specimen to flow from the cup into a lower chamber of the vessel containing a number of chromatographic assay strips. A lid sealing the vessel can include a downwardly projecting guide tube having first barrier sealing a bottom aperture. An oblong initiator can axially engage the guide tube, break the first barrier and open the drain to initiate the test while retaining a pool of liquid specimen in the cup for subsequent confirmatory testing.
Thermal cycler having a temperature analysis and/or verification unit and a method for analyzing or verifying a thermal performance of a thermal cycler and for calibrating the thermal cycler
The invention relates to a thermal cycler (10) comprising a housing (12), the housing (12) accommodating a thermal block (14) having a plurality of sample wells (32), each for receiving a test sample in a sample vessel, electric heater means (18) for heating the thermal block (14), a power supply (24) and an electronic control (22) for controlling the electric heater means (18), and further comprising a temperature analysis and/or verification unit (28) for analyzing and/or verifying a thermal performance of the thermal block (14). The invention further relates to a method for analyzing or verifying a thermal performance of a thermal cycler (10) and for calibrating the thermal cycler (10). The thermal cycler (10) is characterized in that the temperature analysis and/or verification unit (28) is integrated into the housing (12) and is connected to the power supply (24) and to the electronic control (22) by means of an internal interface (26), whereas the method is characterized by the following steps: providing the thermal cycler (10) with an integrated temperature analysis and/or verification unit (28) and using the integrated temperature analysis and/or verification unit (28) for self-calibration of the thermal cycler (10).
Devices and methods for quantification of male fertility
Disclosed herein is a low cost and rapid microfluidic based method and test device for quantifying male fertility potential. The device can simultaneously measure three critical semen parameters rapidly, namely live sperm concentration, motile sperm concentration, and sperm motility. The device includes a transparent substrate and a top sheet with two holes therethrough and an intermediate sheet sandwiched between the substrate and the top sheet. The wells formed by holes form a concentration measuring well (C) and a motility well (M) formed by the top sheet with these two holes bonded to the intermediate sheet. A colorimetric agent is located on the top surface of the intermediate sheet at the bottom of each well which changes color when in contact with sperm. In the motility well a porous membrane is located on top of the colorimetric agent and a liquid buffer may be placed on the top surface of the porous membrane. Applying part of a sperm sample to the C well results in direct contact of any live sperm with the colorimetric agent causing a color change, applying part of the sperm sample to the M well results in live sperm with sufficient motility to swim vertically down through the liquid buffer and through the porous membrane to the colorimetric agent. Evaluating the intensities of the color change of the colorimetric agents before and after contact with the sample gives a measure of total concentration of live sperm and motile sperm from which sperm motility is calculated.
THERMAL CYCLER
Used for running a polymerase chain reaction, a thermal cycler includes a main body having a chamber, and inside of the chamber is provided with a protocol running device port and a sample block for placing reaction tubes. When a protocol running device is put into the protocol running device port, the main body may execute a thermal cycle onto the reaction tubes according to a protocol stored in the protocol running device.
IMMUNOCHROMATOGRAPHIC TEST DEVICE
To provide an immunochromatographic test device capable of accurate diagnosis even when an excess sample is introduced. Provided is the immunochromatographic test device consisting: a test strip; a lower housing including a plurality of support bases that support the test strip; and an upper housing including a dropping hole for dropping a sample into the test strip and a detection window in a direction in which the sample introduced from the dropping hole develops on the test strip, wherein a width of the support base that supports portion of the test strip exposed from the detection window is smaller than a width of the test strip, or wherein among the plurality of support bases, the width of the support base arranged on the lower housing between a position corresponding to the detection window and a position corresponding to the dropping hole is larger than the width of the test strip.
COMPONENT MEASUREMENT SYSTEM, MEASUREMENT DEVICE, AND MEASUREMENT TIP
A component measurement system includes: a measurement tip configured to collect a liquid; and a measurement device configured to measure a component of the liquid by emitting measurement light to the measurement tip. The measurement tip includes: a tip body internally having a detection target region configured to be irradiated with the measurement light, and a printed layer disposed on a surface of the tip body and indicating information relating to a spatial clearance, which is an interval of the detection space along a traveling direction of the measurement light in the detection target region. The measurement device includes: a reading unit configured to read the information relating to the spatial clearance from the printed layer, and a control unit configured to calculate the component of the liquid by using the spatial clearance read by the reading unit.
Systems and methods for reconfigurable point-of-care diagnostics
A reconfigurable point-of-care system, comprising an analysis device having one or more detection components to perform a diagnostic method on a sample, the sample being loaded on a microfluidic chip, wherein the analysis device provides identification information, an interface device coupled to the analysis device to provide a communication channel, and a reader unit coupled to the communication channel and having a processor to select the diagnostic method based on the identification information and reconfigure one or more components of the interface device based on the analysis device.