The present invention relates to a microfluidic device 100 for image multiplexing. The microfluidic device 100 comprises a base structure 110 comprising an optical window 140 and a fluid well insert 120 coupled to the base structure 110. The fluid well insert 120 is configured to retain a microscope slide 130 for mounting of a biological sample 150 within the microfluidic device 100. The fluid well insert 120 is also configured to provide a fluid to said biological sample 150. A fluid well insert lid 160 coupled to the fluid well insert 120 is also provided.

A method for dosing liquid by using a pipette and a syringe, including releasably connecting the syringe to the pipette. Then displaying the dosing volume corresponding to a set dosing increment by using a display apparatus. Next, sucking liquid into the syringe by actuating a drawing lever. Next, detecting a respective position of a drive element along its path of movement when the drive element is shifted along the path. Finally, determining and displaying by the display apparatus a possible maximum number of dosing steps with the set dosing increment without refilling the syringe after executing a reverse stroke starting from a position of the drive element reached at the end of filling.

This disclosure provides systems, apparatuses, and methods for liquid transfer and performing reactions. In one aspect, a system includes a liquid transfer device having a housing having a pipette tip and a plunger assembly; and a reaction chamber, wherein the housing of the liquid transfer device is configured to sealably engage with the reaction chamber. In another aspect, a liquid transfer device including a housing having a pipette tip; and a plunger assembly disposed within the housing and the pipette tip, wherein a portion of the plunger assembly is configured to engage a fluid reservoir such that the plunger assembly remains stationary relative to the fluid reservoir and the housing moves relative to the plunger assembly.

A detection kit for quickly detecting a lead content lead a sample is provided, and belongs to the technical field of medical in vitro immunoassay. The kit includes a detection card and a quality control; the detection card includes a bottom plate, and a sample pad, a glass fiber membrane, a nitrocellulose membrane and an absorbent paper which are arranged on the surface of the bottom plate sequentially from a loading end. The provided kit has advantages of having simple preprocessing, having no need of digestion, and being economic, fast and convenient, and the like, can realize storage at room temperature, a rapid speed, a high throughout, a low instrument cost, simple and convenient operations, single-person packaging, and detection at any time, which greatly improves the simplicity and convenience of clinical use.

One aspect of the invention provides a system for rapid analysis of biological samples. The system includes: a mobile device that receives at least one integrated chip. The mobile device processes the integrated chip to analyze a biological sample loaded thereon. The mobile device and the integrated chip together are configured to perform at least one of manipulation and control of a molecule or a fluidic system on the integrated chip. The mobile device and integrated chip together are configured to precision control at least one parameter that governs at least one of a plurality of steps of the analysis of the biological sample to within plus or minus 10%, plus or minus 1%, plus or minus 0.1%, plus or minus 0.01%, plus or minus 0.001% or plus or minus 0.0001%.

A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.

A test microfluidic strip or cartridge comprising a blood sample collection zone, red blood cell isolation zone, lysis zone, reagents mixing zone, and sensing zone for measuring the enzymatic activity thiopurine methyltransferase is disclosed. The test strip or cartridge is disclosed to be operably connected to a metering device comprising a processor, a display and a memory card.

A “smart ” instrument for mixing (100), a microfluidic chip (50), and a system wherein they are used to prepare formulations is provided. The microfluidic chip comprises microchannels and a programmable data component. The system achieves optimal formulations for RNA, antisense, peptides and small molecules in the hands of even novice users.

A system for performing a molecular analysis workflow includes a reaction holder or a reaction substrate, such as a multi-well reaction plate, with a reaction holder/substrate RFID tag, and/or a reagent container with a reagent container RFID tag, and an instrument and/or device that includes an RFID reader/writer operable to read and/or write information to and from the reaction holder/substrate RFID tag and/or the reagent container RFID tag. The reaction holder/substrate RFID tag and the reagent container RFID tag can be utilized separately or together to send and receive and store information, for example, for a workflow of a molecular analysis, such as a polymerase chain reaction (PCR).

A method for controlling timing of events in a microfluidic device and a timer microfluidic device are disclosed. The method comprises adding a liquid on a first end of a microfluidic device at a first time t.sub.0, the liquid flowing by capillarity towards a second end; producing, by a battery (12) included in the microfluidic device, energy from a second time t.sub.start until a third time t.sub.end to feed an auxiliary device (16) connected to the battery (12). The battery (12) is sized and composed to provide a given amount of energy during a delivery energy time interval t.sub.operation, comprised between a time t.sub.on in which a voltage output of the battery (12) is above a threshold and a time t.sub.off in which the voltage output is below the threshold, to control the duration of an event including a selective activation and deactivation of said auxiliary device (16).