A system for transferring a sample from a sample recovery or provision device to a microfluidic processing device, more particularly an analysis device, preferably in the form of a flow cell, with a sample carrier that removes the sample from the sample recovery or provision device and can be transported to the processing device. The sample carrier can be connected to the sample recovery or provision device and can be detached from sample recovery or provision device, with the sample being automatically removed. The sample carrier connected to the sample recovery or provision device is preferably a functional component of the sample recovery or provision device, more particularly the sample carrier closes a container space of the sample recovery or provision device for receiving sample material.

A system and associated method for concentrating and separating components of different densities from fluid containing cells using a centrifuge includes a syringe and a syringe holder, the syringe having a proximal top with a luer port, a sidewall extending from the top forming a syringe tube, and a plunger slidably disposed inside the syringe tube, the plunger forming a sealing engagement with the sidewall, the syringe holder defining a cavity for receiving the syringe, wherein a distal end of the syringe tube is at least partially closed by the syringe holder after the plunger is placed inside the syringe tube. The method includes receiving a fluid containing cells in the syringe; placing the syringe and syringe holder into a centrifuge; exposing the syringe and syringe holder to elevated g force in the centrifuge, the syringe holder being in physical contact with the sidewall on the distal end to provide support and prevent fluid from leaking outside the syringe; removing the syringe from the centrifuge; and extracting separated layers containing cells using the luer port of the syringe as an access port.

A system and method for tuning and infrared source laser in the Mid-IR wavelength range. The system and method comprising, at least, a plurality of individually tunable emitters, each emitter emitting a beam having a unique wavelength, a grating, a mirror positioned after the grating to receive at least one refracted order of light of at least one beam and to redirect the beam back towards the grating, and a micro-electro-mechanical systems device containing a plurality of adjustable micro-mirrors.

Provided herein is an integrated sampling and testing device, comprising a sampling device that comprises a syringe and specimen collector, and a testing device that comprises a cap, cylindrical container, and adaptor configured for sampling or testing.

An extraction device includes an extraction container including a discharge port and capable of storing a biological sample and an extractant, a discharge accelerator configured to discharge the biological sample extracted into the extractant in the extraction container from the discharge port, and a controller configured to instruct the discharge accelerator to discharge the biological sample from the discharge port.

A transfer container for a fluid includes a tube, the tube including a conical portion at one end, the tube defining an interior space and one or more fluid passages configured to allow flow of fluid into or out of the interior space of the tube. The transfer container also includes a connector configured to seal the end of the conical portion when the connector is joined only to the conical portion and a pressure control mechanism configured to increase or decrease a pressure in the interior space of the tube. The transfer container can be used in a method including connecting fluid lines to the fluid passages, adding a fluid including cryoprotectant and cells, centrifuging the transfer container, and then connecting the transfer container to a second fluid transfer container containing another fluid. This allows the sterile transfer of fluids and separation of cells from cryoprotectant.

A microfluidic valve can include a substrate having a microfluidic channel formed in the substrate. A sealing layer can be over the microfluidic channel. A flexible blister layer can be over the sealing layer. The flexible blister layer can include a blister formed as a distended portion with a blister volume between the flexible blister layer and the sealing layer. The microfluidic valve can be actuatable by puncturing the sealing layer by pressing on the blister. Actuating the microfluidic valve can either allow fluid to flow through the microfluidic channel or block fluid from flowing through the microfluidic channel.

Embodiments of the invention relate to devices for assaying a biomolecule from a plant sample including: a microfluidic cartridge for assaying a biomolecule from a plant sample, including: a top layer; and a bottom layer spaced apart from the top layer in a generally parallel orientation with respect to the top layer, the bottom layer defining a plurality of wells therein that protrude from a surface of the bottom layer; and a filter module for filtering the plant sample, including a filter body defining: an upper portion including an inlet structure forming an inlet channel; and a bottom portion configured to accept and secure a filter membrane. The filter body is configured to accept a microvolume aliquot of the plant sample, the bottom structure includes an outlet structure forming an outlet channel on an outlet side of the filter membrane, and at least one of the plurality of wells includes an assay reagent solution.

The present disclosure provides a cell harvesting method for the efficient sedimentation and retention of cells from liquid samples onto a solid support with low cell losses and low impact on cell morphology.

Disclosed here are kits comprising pre-packed stabilizing solutions for stabilizing combinations of biomarkers demonstrating sufficient accuracy and specificity for identifying kidney injuries. Such kits can be better adapted for sample collection at a subject's dwelling, thus easing the burdensome requirement of continuous monitoring for kidney injury.