Multiplex polymeric dye devices are provided. Aspects of the devices include a solid support, and first and second dried polymeric dye compositions distinctly positioned relative to a surface of the solid support. Aspects of the invention further include methods of making and using the devices, e.g., in analyte detection applications, as well as kits containing the devices.

A system, configured to facilitate processing and detection of nucleic acids, the system comprising a process fluid container and a cartridge comprising: a top layer, a set of sample port-reagent port pairs, a shared fluid port, a vent region, a heating region, and a set of detection chambers; an intermediate substrate, coupled to the top layer comprising a waste chamber; an elastomeric layer, partially situated on the intermediate substrate; and a set of fluidic pathways, each formed by at least a portion of the top layer and a portion of the elastomeric layer, wherein each fluidic pathway is fluidically coupled to a sample port-reagent port pair, the shared fluid port, and a detection chamber, comprises a portion passing through the heating region, and is configured to be occluded upon deformation of the elastomeric layer, to transfer a waste fluid to the waste chamber, and to pass through the vent region.

A blood sample collection and/or storage device includes a two-piece housing that encompasses a port at which a fingertip blood sample is collected. After the sample is taken, the two-piece housing is moved to a closed position to protect the sample for storage and optionally process the sample within the housing. The housing may also be opened to access the stored sample for further processing.

A sample collecting device is provided. The sample collecting device includes a frame, a collect part and a control part. The collect part is disposed in the frame and is provided with a collecting cavity having a collecting port, and the collect part is used to make a sample flow into the collecting cavity from the collecting port. The control part is disposed in the frame, used to make a collecting rod put into a reagent bottle be pulled out and inserted into the collecting cavity to thereby collect the sample, and used to make the collecting rod with the sample be pulled out from the collecting cavity and put back into the reagent bottle. The collecting of sample without manual intervention is realized, effectiveness and consistency of the collected samples are ensured, and the labor cost is reduced.

A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first drive mechanism generates relative movement between the sample block and the baseplate along a first axis. A second drive mechanism generates relative movement between the heated cover and the cover carrier along a second axis that is different from the first axis. Based on a first command the first drive mechanism releasably engages the sample block and operates the second drive mechanism to releasably engage the heated cover with the cover carrier. The system also includes first and second RFID antennas that receive RFID data from the sample holder RFID tag that is read by at least one RFID reader.

A releasing stopper for a container, the stopper including a first body configured to be directly coupled with the container and comprising a coupling element for allowing the removable fastening of the stopper on the container; a second body, axially movable with respect to the first body along a predefined axis of the stopper and cooperating with the first body for defining a reservoir at least temporarily insulated from the outer environment, a membrane or collapsible septum constituting at least a portion of the reservoir wall, openable and/or breakable for allowing the communication of the reservoir with the outer environment. The stopper includes a first closed configuration, wherein the reservoir is insulated from the outer environment, and a second open configuration, wherein the reservoir is in communication with the outer environment, and wherein the membrane or collapsible septum is opened by a perforation or opening element distinct from the stopper.

The present invention relates to an apparatus for performing a nucleic acid amplification reaction and a fluorescence detection device for reaction analysis. The nucleic acid amplification apparatus of the present invention uses a plurality of blocks having different reaction temperatures by independent temperature control and the movement between the blocks is performed along sliding recesses formed in the blocks, enabling to greatly shorten the total amplification time (TAT). In the fluorescence detection device of the present invention, the positions of the light source and the photodetector are very unique for the reaction vessel in which an excitation light is provided and an emission light is generated.

A sample collection device having a sample container, a solid phase binding material, and a container sealing component is presented. The sample container may have a housing that forms an opening for receiving a sample, and that encloses a space for holding the sample. The solid phase binding material may be disposed within the space enclosed by the housing of the sample container and may be adapted, when the sample contains an analyte, to bind specifically to the analyte. The container sealing component may be removably attachable to the sample container at the opening thereof, and may be adapted, when attached to the sample container, to form a seal around the opening of the sample container.

The application is related to a test tube rack, and the test tube rack comprises a first supporting surface and a second supporting surface. The test tube rack further comprises a first hole used for inserting a test tube. The first supporting surface and the second supporting surface can be folded. Such test tube rack can be subject to folding shrink packaging when being packaged and is opened when being used, so that a test tube is inserted to operate.

A container for collecting a sample is provided that can include a housing, an enclosure pivotally coupled to and slidably engaged with the housing, and a sample holder slidably engaged with and received within the enclosure. The sample holder can include a substrate configured to receive the sample. The container in a first configuration can include the enclosure being engaged with the housing to enclose and seal the substrate within an interior volume of the container. The container in a second configuration can include the enclosure exposing the substrate to the ambient environment.