A system and method for receiving and delivering a fluid, the system comprising: a body configured to interface with an opening of a reservoir and defining: a protrusion defining a set position of the body relative to the reservoir; a wall extending from the protrusion; a receiving surface coupled to the wall and sloping from an apex to a nadir along a first direction, the receiving surface comprising a vent; and an outlet positioned closer to the nadir than the apex of the receiving surface and displaced from the vent, the outlet comprising an extension from the body, the extension configured to contact an interior wall of the reservoir, wherein the body comprises: a bubble-mitigating operation mode in which the receiving surface receives and transmits the fluid along the receiving surface, and a fluid-transmitting operation mode in which the body directs the fluid along the interior wall of the reservoir.

A system and method for receiving and delivering a fluid, the system comprising: a body configured to interface with an opening of a reservoir and defining: a protrusion defining a set position of the body relative to the reservoir; a wall extending from the protrusion; a receiving surface coupled to the wall and sloping from an apex to a nadir along a first direction, the receiving surface comprising a vent; and an outlet positioned closer to the nadir than the apex of the receiving surface and displaced from the vent, the outlet comprising an extension from the body, the extension configured to contact an interior wall of the reservoir, wherein the body comprises: a bubble-mitigating operation mode in which the receiving surface receives and transmits the fluid along the receiving surface, and a fluid-transmitting operation mode in which the body directs the fluid along the interior wall of the reservoir.

The present invention generally relates to a sample receiving device for releasably storing a substance. The sample receiving device includes a lid having a reservoir for retaining the substance, and a pierceable barrier sealing the substance within the reservoir; and b) a funnel for receiving a sample and configured for closure by the lid. The funnel is configured for releasable attachment to a sample receptacle such that a sample can be provided to the funnel and travel through the channel in the funnel into the sample receptacle. Further, the funnel includes one or more cutting ribs for cutting the pierceable barrier such that upon cutting of the pierceable barrier the substance is released from the reservoir, flows through the channel in the funnel and into the sample receptacle to be mixed with the sample. The present invention also provides a kit for collecting and storing biomolecules.

An apparatus includes a fluid reservoir and a laminate fluidic circuit positioned above the fluid reservoir. The laminate fluidic circuit includes two or more layers laminated together to define a substantially planar substrate and one or more channels defined within the substrate. The laminate fluidic circuit includes a flexible conduit defined by a portion of the substrate encompassing an extent of at least one of the channels that is partially separated or separable from the remainder of the substrate. The flexible conduit is deflectable with respect to the planar substrate toward the fluid reservoir such that the flexible conduit fluidly connects the at least one channel to the fluid reservoir.

Disclosed here are kits comprising pre-packed stabilizing solutions for stabilizing combinations of biomarkers demonstrating sufficient accuracy and specificity for identifying kidney injuries. Such kits can be better adapted for sample collection at a subject's dwelling, thus easing the burdensome requirement of continuous monitoring for kidney injury.

Disclosed are a reagent holder, a testing apparatus assembly, an aqueous humor collection device and an aqueous humor collection method. The reagent holder (9) comprises a holder body and a functional station arranged on the holder body, wherein the functional station comprises a fluid holding tube insertion hole (91) and an elastic component. The elastic component can elastically act on a fluid holding tube (106) in the case where the fluid holding tube (106) is inserted into the liquid holding tube insertion hole (91) so as to enable the fluid holding tube (106) to elastically move in the direction of the central axis of the hole of the fluid holding tube insertion hole (91). By means of using the reagent holder to elastically fix the fluid holding tube (106), the rigid collision between a fluid drawing device and a bottom wall of the fluid holding tube (106) can be converted into an elastic collision, so as to prevent a testing apparatus from triggering a firing pin protection function during the fluid drawing process, such that the depth to which the fluid drawing device can extend into the tube cavity of the fluid holding tube (106) is greatly increased, and the sample extraction amount is thus effectively increased.

The present invention relates to compositions and methods for preserving and extracting nucleic acids from saliva. The compositions include a chelating agent, a denaturing agent, buffers to maintain the pH of the composition within ranges desirable for DNA and/or RNA. The compositions may also include a reducing agent and/or antimicrobial agent. The invention extends to methods of using the compositions of the invention to preserve and isolate nucleic acids from saliva as well as to containers for the compositions of the invention.

An in vitro diagnostic analyzer and a reagent card. The reagent card includes a reagent card body and a mounting body. The mounting body includes a mounting hole configured to be sleeved on receive a sample tube, a hollow needle disposed in the mounting hole, a sealing portion disposed in the mounting hole, and a gas inlet channel. An end of the hollow needle is capable of being inserted into the sample tube. The sealing portion is capable of being in sealing fit with an outer wall of the sample tube. The gas inlet channel includes a gas outlet hole, a gas inlet hole, and a first flow-stopping structure. The gas inlet hole is disposed in a surface of the reagent card body. The first flow-stopping structure is disposed between the gas outlet hole and the gas inlet hole. The gas outlet hole is configured to be in fluid communication with the sample tube mounted on the mounting hole. The reagent card body includes a sample feeding channel, a test chamber, and a venting end. The sample feeding channel is in fluid communication with a liquid outlet end of the hollow needle. The sample feeding channel and the venting end are both in fluid communication with the test chamber

Microfluidic devices and methods of quantifying fatty acids and/or specialized pro-resolving mediators and/or fatty acid metabolites present in a fluid sample on a microfluidic device are described herein. The methods include extracting fatty acid esters containing fatty acids from the fluid sample, combining the extracted fatty acid esters with a hydrolyzing agent to cleave the fatty acids from the extracted fatty acid esters and form free fatty acids, and quantifying the free fatty acids by performing a bioassay specific to the free fatty acids. Microfluidic devices and methods of quantifying fatty acid metabolites present in a fluid sample on a microfluidic device are also described herein.

A lateral flow assay (LFA) device includes a capillary pad and a sample port that holds the sample fluid before a hole is made in a cavity surface of the sample port. The LFA device includes a breaker with a tip to make a hole in the cavity wall of the sample port causing the sample fluid held inside the compartment to be applied to the capillary pad after the start of a test.