A method, computer program product, and apparatus are provided for controlling components of a detection device. The device may detect turbidity of liquid with sensors such as a density sensor and/or nephelometric sensor. A light modulation pattern may reduce or eliminate interference in sensor readings. Readings may be performed during off cycles of an illumination light to reduce interference but to provide improved visibility of a tube. Dark and light sensor readings may be performed with an emitter respectively off or on to account for ambient light in subsequent readings. Readings from the density sensor and/or nephelometric sensor may be used to calculate McFarland values. The device may be zeroed based on an emitter level that results in a sensor reading satisfying a predetermined criterion.

Provided are a cupping device and a blood analysis apparatus using the same. The cupping device includes a cupping cup having a first opening defined in a lower portion thereof, at least one blood collecting container disposed adjacent to an outer surface of the cupping cup and having an accommodation space configured to accommodate blood therein, and a connecting pipe disposed between the cupping cup and the blood collecting container to connect an inner space of the cupping cup to the accommodation space of the blood collecting container.

Accordingly, in some embodiments of the disclosure, a multi-chambered assay device is provided, which is configured for arrangement on a disc, as well as configured to process an individual sample. A plurality of such assay devices can be arranged along a periphery of the disc at a distance/radius from the center, such that a plurality of individual samples can be processed, e.g., one per assay device. In addition, in an arrangement that a plurality of assay devices are used, they can be spaced apart such that they balance the disc during rotation (which can be with samples contained in one or more of the assay devices, a plurality, a majority, or all of the assay devices).

The present disclosure provides an automated sample analyzer having a continuous scanning optical assembly for performing an assay. The optical assembly allows for robust detection of light emitted from a reaction mixture in a dynamically changing environment, such as detection of light from a reaction mixture that is being rotated about an axis at high rotational velocity.

The present invention relates to fluidic devices for preparing, processing, storing, preserving, and/or analyzing samples. In particular, the devices and related systems and methods allow for preparing and/or analyzing samples (e.g., biospecimen samples) by using one or more of capture regions and/or automated analysis.

A rapid test device includes a micropad chip configured for a multi-parameter chemical testing of an input sample. A plurality of paper layers of the micropad chip are in fluid communication, including a sample absorption element, a filtering element configured to filter the input sample, and a sample distribution element configured to distribute the input sample received from the filtering element to a remainder of the plurality of paper layers. One or more reacting elements associated with the multi-parameter chemical testing of the input sample have one or more colorimetric reagents in fluid communication with the sample distribution element. A colorimetric result displaying element in fluid communication with the one or more reacting elements is configured to display a colorimetric result of the testing of the input sample with the at least one reacting element for a respective chemical test of the multi-parameter chemical testing.

A sample analysis substrate includes a substrate; a first holding chamber; a reaction chamber; a first flow path having a first opening and a second opening respectively connected with the first holding chamber and reaction chamber; a main chamber; a second flow path having a third opening and a fourth opening respectively connected with the reaction chamber and the main chamber; and a magnet accommodation chamber capable of accommodating a magnet. The first opening is located closer to a rotation shaft than the second opening. The second opening is located closer to the rotation shaft than the third opening. The magnet accommodation chamber is located at a position at which, in the case where the magnet is accommodated in the magnet accommodation chamber, the magnet captures magnetic particles in the main chamber. The sample analysis substrate is rotatable to transfer a liquid.

Device (1) for the storage and selection of cartridges (20) that are pre-filled with reactive discs to be placed on a support of the type comprising a plurality of magazines (2) each able to store a cartridge (20) of discs, at least one magazine-holding support (3) and, for each support (3), drive means (4) for moving the magazine-holding support (3). The device (1) comprises a chamber (5) configured to house at least one magazine-holding support (3), said chamber (5) being fitted with a cooler (6) and provided with at least one placement opening (7) facing which the drive means (4) for rotating a magazine-holding support (3) are configured to position at least one magazine (2) of said support (3) in what is referred to as the placement configuration of said magazine (2), and the device (1) comprises a drive mechanism (8) driving the movement of the magazine (2) in the placement configuration between a position in which said magazine (2) is distant from and a position in which same is closer to the placement opening (7) of the chamber (5).

Microfluidic systems and methods are described for capturing magnetic target entities bound to one or more magnetic beads. The systems include a well array device that includes a substrate with a surface that has a plurality of wells arranged in one or more arrays on the surface. A first array of wells is arranged adjacent to a first location on the surface. A second and subsequent arrays, if present, are arranged sequentially on the surface at second and subsequent locations. When a liquid sample is added onto the substrate and caused to flow, the liquid sample will flow across the first array first and then flow across the second and subsequent arrays in sequential order. The wells in the first array each have a size that permits entry of only one target entity into the well and each well in the first array has approximately the same size.

The present disclosure relates to a cell extraction device comprising: a plurality of cell extraction modules arranged in a single layer array, the single layer array having a cell-receiving side wherein an opening of at least one of the plurality of cell extraction modules on the cell-receiving surface is configured to receive and retain a single target cell from a fluid sample, and a fluid-evacuating side wherein an opening of the or each of the plurality of cell extraction modules on the fluid-evacuating side is configured to allow fluid from the fluid sample to be evacuated from the cell extraction device, wherein at least one of the plurality of cell extraction modules comprises a micropore capillary configured at a first end that is open on the cell-receiving side to receive a target cell, and configured at a second end that is open on the fluid-evacuating side to allow fluid to pass through.