A biochemical detection device is revealed. The biochemical detection device includes a cap and a base arranged at two ends of a test tube correspondingly and a driving member disposed on the base. A sample-mounting slot and a test-paper-mounting slot separated from each other are formed in the test tube. After sampling, a sample obtained is placed into the sample-mounting slot and mixed with an extraction solution therein. A thin-film on the sample-mounting slot is penetrated by the driving member to allow the extraction solution mixed with the sample flowing into a cavity of the test tube to react with a test strip in the test-paper-mounting slot. The test cost is reduced and the detection efficiency is improved due to simple structure and easy operation. Moreover, the sample and the extraction solution are sealed in the test tube to prevent environmental pollution caused by spread of viruses.

Broadly speaking, embodiments of the present techniques provide a liquid handling device that enables a user to more easily and efficiently perform sample dilutions, without requiring the user to perform any calculations or be in a controlled environment (e.g. a laboratory or sterile/aseptic environment). Advantageously, this may enable a user to perform sample dilutions and subsequent sample processing outside of a laboratory, such as during field work, or in environments, regions or countries where access to sterile/aseptic environments may be difficult or nonexistent. The device may be used to dilute any liquid sample, such as biological samples, chemical samples, or environmental samples (e.g. liquid samples taken from a river or lake, or soil samples that are mixed with liquid).

Sample processing methods and systems to collect a biological sample. A device may be configured collect a predetermined volume of a sample in sample chamber, and seal the chamber upon activation. The device may be further configured to mix the mix the sample with a predetermined volume of a reagent and/or mix the sample and the reagent in a pre-determined ration.

The invention relates to physiological sensor for measurement of carbon dioxide and a method of securing a carbon dioxide permeable membrane of the physiological sensor. The physiological sensor comprising a closed chamber containing a sensor liquid and being bounded, at least partially, by a carbon dioxide permeable membrane (12), at least two electrodes (10) provided within the chamber in contact with the sensor liquid, a support structure (23) for supporting the membrane (12); and at least one filament 28) wound around the support structure (23) and on top of the membrane (12) for securing the gas-permeable membrane (12) to the support structure (23).

A sample chamber holder for MAS-NMR capable of operating at both low and high pressures. In one example the sample chamber holder is made up of a sample holder body defining a sample chamber therein, a connector configured to operatively statically hold an in situ rotor within the sample chamber; a coupler configured to operatively connect the sampler holder body to a magnetically coupled rotation member. The magnetically coupled rotation member is configured to engage and rotate a sealing cap from an NMR rotor in such a way so as to allow an NMR cap to be alternatively opened or sealed in-situ while the NMR rotor remains statically positioned in an NMR device.

The present invention discloses a method for preparing a micro-channel array plate, comprising the steps of : (1) arranging a first optical fiber glass rod and a second optical fiber glass rod closely, melting the two glass rods into a whole at a high temperature to obtain a melted glass rod, drawing the melted glass rod at least one time into a longer and thinner glass rod than the melted glass rod, and cutting the drawn glass rod into small pieces to obtain a micro-channel array plate blank, wherein the corrosion resistance of the first optical fiber glass rod and the second optical fiber glass rod to the same corrosive liquid is different; (2) corroding the micro-channel array plate blank by a corrosive liquid to obtain a micro-channel array plate crude product with through holes; and (3) conducting hydrophobic treatment on the micro-channel array plate crude product to obtain the micro-channel array plate.

A portable motorized centrifugal system is optimized for low cost manufacture and operation. Separation of inhomogeneous fluid biological samples, such as liquid plasma from whole blood, is a common step in medical diagnostic tests. This system may enable remote separation where access to plug-in power sources are limited. The system may facilitate at-home testing. Due to biohazard concerns, the entire centrifugal apparatus portable and disposable, or the system includes one or more disposable elements within the interior of the centrifuge. Alternatively, the system may contain a module of higher value components that are re-usable after disinfection. Devices and methods for implementing centrifugal separation may include disk-shaped fluidic cartridges and tubes with reduced drag cross-section.

Devices, systems and methods are disclosed which relate to a prefiltration device that can be used with the concentrating pipette instruments and other devices which draw a sample in through one opening and dispense a concentrated or eluted sample out through the same opening. The device allows the sample to be passed through a prefilter when entering the opening and then bypassed the prefilter when being dispensed through the same opening.

Provided herein, among other aspects, are methods and apparatuses for analyzing particles in a sample. In some aspects, the particles can be analytes, cells, nucleic acids, or proteins and contacted with a tag, partitioned into aliquots, detected by a ranking device, and isolated. The methods and apparatuses provided herein may include a microfluidic chip. In some aspects, the methods and apparatuses may be used to quantify rare particles in a sample, such as cancer cells and other rare cells for disease diagnosis, prognosis, or treatment.

Apparatus and methods for separating blood components are disclosed in which an apparatus for separating blood generally includes a tube defining a channel and configured for receiving a quantity of blood and a float contained within the tube and having a density which is predefined so that the float is maintained at equilibrium between a first layer formed from a first fractional component of the blood and a second layer formed from a second fractional component of the blood. Upon completion of the centrifugation, the first layer may be removed from the tube while the float isolates the second layer from the first layer.