A system for collecting biomolecules comprising an extractor assembly comprising a top cap, an extractor core, an extractor core adaptor, an extractor body having an internal volume, and a bottom cap ring. The top cap comprises a sample connection port and is configured to be secured to the extractor body by the bottom cap ring. The extractor core is adapted to be removably attached to a connection interface of the top cap and contains a substrate for collecting the biomolecules. The extractor core adaptor has an upstream open end for mating with the downstream end of the extractor core and a downstream protrusion configured to project through an opening in the extractor body. Methods for using the system to collect samples for transport and further processing to detect disease are also disclosed.

The present invention provides a method and apparatus for evaluating the margins of a surgically-removed tissue specimen, such as a breast tissue specimen, to determine whether sufficient fatty tissue has been removed from around the lesion or cancerous point. The instant invention provides a solution to the problem of on-site evaluation of the margin sufficiency during the surgical procedure, in that it provides surgeons with an orthogonal view of all sides of the tissue specimen to be evaluated. The specimen evaluation device provides for properly-oriented examination of the removed specimen in a non-compressed, undistorted manner, both by visual inspection and through radiographic evaluation. Through this examination of the properly-oriented specimen, the surgeon may quickly and more accurately be informed of whether there remain cancerous cells in the margins surrounding the sample, which are meant to be free of cancerous cells. Upon evaluation of the margins of the removed sample, the surgeon may then make an on-site determination on whether to proceed with additional surgery or complete the surgical procedure.

A method of analyzing a fecal sample containing parasitic material and non-parasitic material. The fecal sample is first deposited into a carrier containing a flotation medium. The carrier is then shaken to disperse the fecal sample in the flotation medium. The fecal sample is then allowed to settle under gravity or by centrifugation. A filter device is then inserted into the carrier to separate the parasitic material from the non-parasitic material and to collect the parasitic material. The collected parasitic material is then poured into a capture filter for analysis.

An oral sample collection system configured to draw and deliver an oral sample to a first analyte testing device (such as a local dry reagent test), and then allow the same sample to then be retested at a remote laboratory. The system uses a swab holder with a hollow tubular handle, an outer swab mounted at one end of the handle, and an inner swab mounted on a carriage positioned inside the hollow handle. Sample is collected in both swabs, the outer swab sample used for immediate testing, and the inner swab sample retained for later retesting as needed. This device may be used with a collection container configured to accept the swab holder and conduct immediate tests on the outer swab sample. Various applications, including utility for drugs of abuse testing, are also discussed.

A fluid specimen collection, storage, transport, and testing cup contains a removable chromatographic strip-carrying cartridge and an axially moveable liquid specimen preserving caddy which moves between a first, pre-test position and a second, post-test position. During which a caddy drain is temporarily opened allowing an amount of liquid specimen deposited in the caddy to flow into the cup and contact the strips. Once in the second position, the drain is sealed for later confirmatory testing. The caddy is moved between the two positions by screwing a threaded lid more tightly onto the top opening of the cup. The axial range of the screw is limited by a removable obstruction collar. The caddy can include a liquid specimen containing chamber having a lower opening sealed by a frangible barrier.

An analytic device comprising a device housing, a dock to receive a camera enabled mobile electronic device, such as a smartphone and other smart devices, and a processing device to communicate with the mobile electronic device and to control a condition of the assay tube, such as temperature. In another example, the analytic device comprises a device housing and a circuit board. A processing device, a heating block defining a recess to support assay tube, and a resistive heater are surface mounted to the circuit board. A light source and a fan are also provided. A dock may be provided to support a mobile electronic device. The mobile electronic device communicates with the processing device to cause the application of reaction conditions to the assay tube, to perform a PCR procedure, for example. Methods are also disclosed.

This disclosure is directed to methods and devices (300) associated with Point of Care medical testing and diagnostics. More specifically, methods and devices are described which provide a quick and streamlined way to prepare blood samples for analysis using flow cytometers, microscopes, and other analysis platforms. The benefits include a reduction in the time, resources, and expertise needed for preparing those blood samples without compromising the accuracy and efficacy of diagnosing diseases or identifying specific particulates from those blood samples.

The invention relates to a system is provided that comprises a lysis chamber, an amplification chamber and a fluorescence detection device. The fluorescence detection device (16) comprises - a detection chamber (42) configured to receive the amplification chamber (14) or the contents of the amplification chamber, - a light source (44), - an optical sensor (46), - energy supply means (48), - a wireless data interface (52) and - a controller (50).

Disclosed herein are systems and methods for detecting ocular analytes in vitreous humor or aqueous humor. Specifically exemplified are systems having a sample acquisition device that is inline with an analyte detection device. The system embodiments allow for the easy procurement and testing of samples. In a typical embodiment, the analyte detection device includes a sample staging chamber and a test chamber that comprises reagents that specifically interact with the analyte. The test chamber may include a sample pad, a conjugate pad having at least one conjugate reagent specific to the analyte loaded thereon, an assay platform having a substrate with at least one test region having a test reagent immobilized thereon, the test reagent being specific to the analyte; and an optional absorbent pad.

A sample collection system can include a sample collection vessel having a sample collection chamber with an opening configured to receive a sample into the sample collection chamber. The sample collection system can additionally include a selectively movable sleeve valve configured to associate with the opening of the sample collection chamber. The sample collection system can include a sealing cap that is configured to associate with the selectively movable sleeve valve and with the sample collection vessel. The sealing cap can include a reagent chamber having reagent(s) stored therein, and when the sealing cap is associated with the sample collection vessel, the selectively movable sleeve valve opens, dispensing the reagent(s) into the sample collection chamber. When the selectively moveable sleeve associates with the sample collection chamber, an outer sleeve slides relative to an inner vessel, opening the sleeve and dispensing reagent into the sample collection chamber.