B01L2300/0832

ELECTROMAGNETIC SAMPLING DEVICE PROTECTED IN A SEPTUM PIERCING NEEDLE
20230096792 · 2023-03-30 ·

An electromagnetic sampling device is disclosed, which comprises a needle having a hollow housing that extends from a proximal end to a distal end, and an electromagnet comprising an electromagnetic coil and a metal core, at least a portion of said metal core extending through said hollow housing of the needle and be configured to transition between an extended position in which the distal end of the metal core extends beyond the distal end of the needle's hollow housing and a retracted position in which the distal end of the metal core is positioned within the needle's housing, wherein an activation of said electromagnetic coil magnetizes the metal core.

Bacterial test plate having antibacterial agent introduced thereinto, and transparent plate

Provided is an antibacterial agent-containing dried plate having no cracks on an observation surface (a part of the plate corresponding to an observation visual field of a microscope). According to the present embodiment, an antibacterial agent-introduced plate obtained by introducing an antibacterial agent and performing vacuum drying has a recess at an edge of a well, and a microscopic observation portion, which has a surface substantially parallel to a well bottom surface, near the center of the well. The recess is provided between the microscopic observation portion and a side wall of the well, and is lower in height than the microscopic observation portion. Further, at least the bottom surface of the well and the microscopic observation portion are made of a material having a light-transmitting property in order for optical measurement (FIG. 1).

AUTOMATED SAMPLE EXTRACTION APPARATUS AND METHOD
20230094765 · 2023-03-30 ·

An automatic nucleic acid extraction cartridge and an automatic nucleic acid extraction system including the same are described herein. The cartridge having a housing that includes a sample port, a cell processing chamber, a wash fluid chamber, a filter assembly comprising a filter member, and a diverter valve having a first and a second reversibly sealable output, wherein each of the sample port and the cell processing chamber, the cell processing chamber and the filter assembly, and the wash fluid chamber and the filter assembly are in one-way fluid communication, and the filter assembly is in fluid communication with the diverter valve and (i) a waste conduit when the diverter valve is biased to the first reversibly sealable output and (ii) a pathogen nucleic acid conduit when the diverter valve is biased to the second reversibly sealable output. The present disclosure further describes methods of using the same.

OPTOFLUIDIC DIAGNOSTICS SYSTEM
20230036216 · 2023-02-02 ·

An optofluidic diagnostic system and methods for rapid analyte detections. The system comprises an optofluidic sensor array, a test plate and an optical detection cartridge. The sensor array supports one or more distinct sensor units, each having a reactor section designed to temporarily enter a series of different kinds of wells in the test plate. One kind of well is a sample reservoir that holds reagent solution to be transferred into the reactor section. Another kind of well is a drainage chamber that removes reagent solution from the reactor section. A third kind of well is a colorant reservoir that holds a colorant reagent transferable into a reactor section. Finally, the sensor unit is transferred to the optical detection cartridge where it is placed into an isolation booth during the optical detection process so that its flat observation face is stationed in a viewing window opposite an optical detector lens.

REAGENT SLEEVE SYSTEM
20230031105 · 2023-02-02 ·

A reagent sleeve system such as can be used with various analyzers using chemical phenomena, analyzers and methods of using the reagent sleeve system and analyzer are described. The reagent sleeve system can include a reagent sleeve; and a plurality of removable reagent reservoirs located within the reagent sleeve, wherein each of the plurality of removable reagent reservoirs comprises a respective peripheral wall, and first and second end walls, whereby each of the plurality of removable reagent reservoirs contains a reagent located therein, and the first end wall is pierceable by a reagent extractor, and the reagent sleeve comprises a peripheral wall that encompasses the plurality of removable reagent reservoirs and holds the plurality of reagent reservoirs for sequential use.

ALL-IN-ONE SELF TEST KIT
20230036013 · 2023-02-02 ·

An all-in-one self test kit includes: a test tool having a reagent container adapted to store a diagnosis reagent therein and a diagnosis kit with a casing constituted of a first body and a second body and a diagnosis strip disposed inside the casing and having a sucking part for sucking the diagnosis reagent and a diagnosis part reacting to the diagnosis reagent sucked to the sucking part; a sub-body having a container insertion portion for inserting the reagent container thereinto and a kit insertion portion for inserting the diagnosis kit thereinto; a main body for inserting the sub-body thereinto; and a cap fastened and unfastened with an entrance of the main body to open and close the main body.

METHODS, DEVICES, AND KITS FOR PURIFYING AND LYSING BIOLOGICAL PARTICLES

Devices, kits, and their methods of use for lysing and/or purifying biological particles, e.g., nuclei are provided. One or more thixotropic layers can be employed in a vessel to purify biological particles. A device with sharp features may be employed to lyse biological particles or the contents thereof.

Sampling assembly, sample analyzer and sampling method

A sampling assembly, including a sampling needle, a first pipeline, a second pipeline, a driving member, a first switching member, and a second switching member, is disclosed. The first pipeline is connected between the sampling needle and the first switching member. The second pipeline is connected between the first switching member and the driving member. The first switching member is used for connecting or disconnecting the first pipeline and the second pipeline. The second pipeline is connected, by means of the second switching member, to a negative pressure source. The sampling time of the sampling assembly of the present disclosure is relatively short. The present disclosure further discloses a sample analyzer and a sampling method.

SPERM SORTING DEVICE AND METHOD
20230031283 · 2023-02-02 ·

A sperm sorting device suitable for selectively isolating motile sperms from a semen specimen includes a base and a sorting unit. The base comprises a central protruding block including a truncated cone-shaped surface, a bottom wall that surrounds the central protruding block, and an intermediate ring. The intermediate ring connects to the bottom wall via an inner wall surface. The sorting unit includes a sorting ring and a protruding ring. The sorting ring includes a central hole for a sorting filter that filters the semen specimen and is beveled at an angle that increases a permeable surface of the sorting filter. The protruding ring connects to the sorting ring via an inner sleeve surface. The sperm sorting device enhances sperm sorting quality by allowing the motile sperms to swim upward through the first sorting filter naturally.

Microfluidic device

The present invention may provide a microfluidic device including a rotatable body; a first chamber positioned in a direction of an inner wall of the body; a second chamber positioned in a direction of an outer wall of the body from the first chamber; and a backflow prevention unit, and wherein a fluid is transferred from the first chamber to the second chamber, and wherein the backflow prevention unit prevents a backflow of the fluid from the second chamber to the first chamber.