Provided is a cell capturing cartridge. According to an embodiment of the inventive concept, the cell capturing cartridge may include a substrate and structures provided on an upper surface of the substrate and constituting a plurality of rows that are parallel to a row direction. The structures in one row may be offset from the structures in the neighboring rows in the row direction. Each of the substrates may have a first side surface facing one side of the substrate and a second side surface disposed opposite to the first side surface and having a width greater than that of the first side surface.

Aspects of the present disclosure include systems that include reaction vessels and reaction vessel caps. In certain aspects, the reaction vessels include a reaction chamber and a groove disposed around a top opening of a reaction chamber. The system also includes a RV cap that includes a cap body, a RV plug, and a lower wall that includes an outer radial groove disposed above an outward projecting ridge of the lower wall. When the cap is inserted into the RV, the RV plug of the RV cap is sealingly inserted into the reaction chamber of the RV, a ridge of the RV mates with the outer radial groove of the RV cap, and an outward projecting ridge of the RV cap mates with the radial groove of the RV. Also provided are methods and sample analysis systems, which may employ the RV/RV cap systems of the present disclosure.

Aspects of the present disclosure include sample preparation cartridges including a frame that includes a plurality of wells integrated therewith, where the plurality of wells have a closed bottom and an open top. The frame further includes an opening within the frame having a reaction vessel (RV) or RV cap removably disposed therein, where the plurality of wells and the opening are linearly arranged relative to each other. Also provided are sample preparation cartridges that include a frame, two or more cartridge separation projections on a top side of the frame, and two or more cartridge separation projections on a bottom side of the frame. The cartridge separation projections separate the cartridge and a different cartridge when the cartridge and different cartridge are stacked. Methods of using the sample preparation cartridges, as well as nucleic acid sample preparation units that include the sample preparation cartridges, are also provided.

The invention relates to a biological sampling and storage container comprising a top cover and a bottom cover adapted to fit onto each other; and a sampling element having a proximal end onto which the top cover fits and a distal end onto which the bottom cover fits, said sampling element further comprising a sampling container comprising a sampling chamber for accepting the biological sample; an aliquoting element removably mounted on and in said sampling container, said aliquoting element comprising a structural element onto which one or more aliquoting chambers are positioned; and optionally, an ejector removably mounted onto said aliquoting element, wherein the ejector comprises an ejector wand fitting into the aliquoting chambers.

In an example, a method for preparing a nucleotide solution includes flowing an aqueous solution from an initial solution storage of a sequencing instrument continuously through a container fluidically coupled to the sequencing instrument, the container comprising a nucleotide concentrate; and collecting the aqueous solution with nucleotide in a storage container.

Microarray slide holders for loading multiple microarray slides into a microscope system are disclosed. An apparatus for simultaneous microengraving and imaging of microwell arrays is disclosed. Also disclosed is a liquid run-off tray for simultaneous processing of multiple microarray slides.

Disclosed is a test barrel, to prevent a test liquid in the barrel from sputtering into a connection gap due to shaking of the barrel to hence cause contamination, improve the measurement accuracy in case of multiple tests, and meanwhile improve the operability of screwing on and screwing off the entire device during use of the device. The above technical objective of this utility model is implemented by employing the following technical solution: a test barrel, comprising barrel lid and a barrel body; wherein the threaded rings are arranged on an inner wall of a side face of the barrel lid and an outer wall of an opening of the barrel body, a rotary force applying portion is arranged on an outer wall of the side face of the barrel lid, and during engagement, a liquid blocking washer is arranged between the barrel lid and the barrel body, wherein a radial width of the liquid blocking washer is greater than a thickness of the opening of the barrel body.

Provided is a microfluidic device including a lower panel including flow velocity measuring structures for measuring a flow velocity of a fluid; an upper panel separated from the lower panel and including a microfluidic channel through which a sample passes; a thin film provided at a portion where the lower panel and the upper panel adjoin each other in order to prevent the sample passing through the microfluidic channel from coming into direct contact with the flow velocity measuring structures, the thin film being configured to separate the lower panel and the upper panel to enable the lower panel to be repeatedly used multiple times; a specific functional unit configured to perform a specific operation on the sample passing through the microfluidic channel; and a negative pressure forming means configured to suck the lower panel and the upper panel with a negative pressure.

A sampling system can include a cassette assembly coupled to a station base that has a plurality of actuators. The cassette assembly can include a cassette base, a cassette top, and an elastomer membrane disposed between the cassette base and cassette top. The cassette base can include a sample inlet, a reservoir for receiving a sample from the sample inlet, a sample outlet, and a fluid flow path extending between the sample inlet, the reservoir, and the sample outlet.

An apparatus for measuring an electrophysiological signal of a three-dimensional (3D) cell and a method of fabricating the apparatus. The apparatus includes a flexible substrate including a plurality of protrusions, and a conductor formed on the plurality of protrusions, and regions other than the plurality of protrusions are partially removed from the flexible substrate.