The present disclosure discloses an array substrate and a micro total analysis device. The array substrate includes: a substrate, a plurality of pixel regions arranged on the substrate and defined by the intersection of a plurality of data lines and a plurality of gate lines, and a plurality of drive transistors arranged in the plurality of pixel regions respectively; each drive transistor includes a first active layer pattern, a first extension direction of the first active layer pattern forms a first preset angle with a gate line, and in a first preset angle direction, the first active layer pattern spans a pixel region in an inclined manner; and source and drain electrodes of the each drive transistor are coupled with the active layer pattern in the first preset angle direction.

Spectrophotometric measurements on highly absorbing turbid samples face technical challenges that can be solved by reducing a path length of an optical chamber used during measurement. Reducing the path length requires exceptional control of variables that may be difficult to achieve in unit-use and inexpensive cuvettes. The invention provides a precise inexpensive method for producing an optical cavity useful in making spectrophotometric measurements on high attenuation liquid samples. Two components are shaped such that, when in contact, a central optical chamber and peripheral groove are formed. Liquid adhesive dispensed into the groove wicks around the interface perimeter, sealing the components together when cured. This results in a short precisely controlled path length that reduces chances of mechanical induced distortions (that arise with other bonding methods). The invention provides for manufacturing of a consistent optical chamber with very short path length within a diagnostic cartridge or cuvette.

A second device includes a first surface, a second surface in contact with a first device, and a first hole extending through and between the first surface and the second surface and being continuous with a groove on the first device. A third device includes a third surface in contact with the first surface, a second hole open in the third surface and continuous with the first hole, and a flow path continuous with the second hole and open in the third surface. As viewed in a first direction from the first surface to the second surface, the first hole includes at least one vertex surrounded by the second hole, and a pair of sides joined to the at least one vertex and widening toward the flow path to define a minor angle.

The invention(s) cover systems and methods for target detection in a multiplexed and rapid manner. Embodiments of the system can include: a base substrate; and an array of sample processing regions defined at a broad surface of the base substrate, wherein each of the array of sample processing regions includes: a set of microwell subarrays arranged in a gradient by volumetric capacity between an upstream end and a downstream end of each respective sample processing region, and a boundary separating each respective sample processing region from adjacent sample processing regions. The system can support methods, with example implementation by an automated platform, for returning preliminary results from a subset of microwells of the samples processing regions, as well as results pertaining to specific and non-specific amplification, for multiple targets of a sample.

An optofluidic diagnostic system and methods for rapid analyte detections. The system comprises an optofluidic sensor array, a test plate and an optical detection cartridge. The sensor array supports one or more distinct sensor units, each having a reactor section designed to temporarily enter a series of different kinds of wells in the test plate. One kind of well is a sample reservoir that holds reagent solution to be transferred into the reactor section. Another kind of well is a drainage chamber that removes reagent solution from the reactor section. A third kind of well is a colorant reservoir that holds a colorant reagent transferable into a reactor section. Finally, the sensor unit is transferred to the optical detection cartridge where it is placed into an isolation booth during the optical detection process so that its flat observation face is stationed in a viewing window opposite an optical detector lens.

A test strip system having containers and suitable carriers therefor. The test strip assembly is suitable for carrying out different types of chemical, biological or biochemical tests and evaluating them using a suitable analysis device. The test strip assembly has a first region having at least one container and a second region also having at least one container. The container of the first region has a flat transparent bottom, and the container of the second region has a V-shaped or U-shaped bottom.

A thin-walled microplate suitable for use in the Polymerase Chain Reaction (PCR) technique comprising a plurality of thin-walled tubes or wells arranged in a fixed array, each well having an upper portion with an open top and a lower, frustoconical portion having a substantially flat bottom.

The present invention relates to provide, among other things, the methods, devices, and systems that can simply and quickly collecting and analyzing a tiny amount of vapor condensates (e.g. exhaled breath condensate (EBC)).

A sample of water is tested for silica and phosphate content in a single apparatus. In the test method, a first sample of the water is colorimetrically analyzed in a reaction chamber using a “molybdenum blue” test in which silica and phosphate in the sample are complexed with a first reagent. The phosphate complexes are then optically inactivated by a second reagent and the color of the silica complexes is intensified with a third reagent. From this, the silica content is calculated. A further sample is colorimetrically analyzed without using the second reagent, so that a combined silica and phosphate content of the further sample is obtained. A value of the silica content is subtracted from the value of the combined silica and phosphate content, resulting in a phosphate content for the sample. The silica content and the phosphate content of the sample are reportable.

In one configuration, a handheld compound tester to process and detect presence of a compound in a tablet is disclosed. The handheld compound tester may include a sampling chamber configured to receive a tablet and a lid couplable with the sampling chamber. The coupling of the lid with the sampling chamber may cause cutting of the tablet. A liquid may be added inside the sampling chamber to create a mixture with segments of the tablet. The mixture may be then received by a housing adjoining the sampling chamber. A test strip disposed within the housing, upon contacting the mixture, may be configured to indicate a presence of the compound in the mixture.