Methods and devices are provided for executing temperature-controlled shipment of relatively small temperature-sensitive payloads. A vacuum shipper may include a vacuum container and a PCM pack with an outer wall broadly form fitting to the vacuum container. The PCM pack includes a payload cavity and may be pre-conditioned at an effective charging temperature for an effective charging time. A temperature-sensitive payload is placed in the payload cavity. An insulated stopper is pressed into a mouth of the vacuum container. The vacuum shipper may then be conveyed by commercial express freight to its destination within an effective endurance time.

A handheld dispensing device has a first dispensing element configured to dispense a structural material and a second dispensing element configured to dispense a biological material. The second dispensing element is single-use and sterilizable. The first dispensing element is connectable to the second dispensing element. A dispensing system also is provided and has a sterilizable chamber; at least one robotic arm assembly and a dispensing device within the sterilizable chamber. The at least one robotic assembly is configured to move the dispensing device that has a first dispensing element and a second dispensing element. The first dispensing element is releasably connectable to the second dispensing element. An external control is device connected to the robotic arm assembly and controls the at least one robotic arm assembly. The first dispensing element dispenses a structural material and the second dispensing element dispenses a biological material.

A dispensing system has a sterilizable chamber. At least one robotic arm assembly and a dispensing device are within the sterilizable chamber. The dispensing device comprising a first dispensing element and a second dispensing element. The first dispensing element is connectable to the second dispensing element The at least one robotic assembly is configured to move the dispensing device. An external control device is connected to the at least one robotic arm assembly and is configured to control the at least one robotic arm assembly. The first dispensing element is configured to dispense a structural material and the second dispensing element is configured to dispense a biological material.

The present invention provides devices, systems, and methods for rapid and easy-to-use in sample thermal cycling or temperature changes for the facilitation of reactions such as but not limited to PCR.

Disclosed is a measuring arrangement for measuring the total nitrogen bound (TN) in a measuring liquid, comprising: a radiation source emitting UV radiation; a radiation receiver configured to generate a signal that depends on the intensity of radiation impinging on the radiation receiver; a vessel having a first opening and a second opening opposite the first opening; a first window closing the first opening; and a second window closing the second opening. The first and second windows are transparent to the measuring radiation. The measuring radiation emitted by the radiation source propagates along a measuring path which extends from the radiation source through the first window, the vessel, and the second window to the radiation receiver. The measuring arrangement also includes a heating element in thermal contact with the vessel wall.

A temperature-control device for receiving a reaction vessel having a heat-insulated interior space and which is covered by a lid. The reaction vessel has a hollow body and a cap, this hollow body being closed on one side by a base. The base contacts a heatable heating block in order to heat a sample located in the reaction vessel. The hollow body is surrounded by a heatable heating body which communicates with the lid via a heat-conducting contact region so that the heating body heats the hollow body directly and heats the cap indirectly via the lid.

Provided is a safety cabinet that reduces a temperature change between a storage environment temperature and a temperature in the safety cabinet to reduce damage to cultured microorganisms, cultured cells, or the like. The safety cabinet that includes a front panel and an operation opening in front of an operation space and an operation stage below the operation space and supplies purified air into the operation space from above, in which the operation stage is provided with a temperature-regulatable portion of which a temperature is regulatable.

A digital microfluidic chip, a method for driving the same, and a digital microfluidic device are provided. The digital microfluidic chip includes a state transition layer configured to bear a droplet, and a light driving layer configured to provide light for controlling a lyophobicity-lyophobicity transition of the state transition layer to drive the droplet to move. The light driving layer includes light emitting units arranged in an array and provides light. The state transition layer realizes a lyophobicity-lyophobicity transition. The light driving layer controls the lyophobicity-lyophobicity transition by providing light to drive the droplet to move. An existing digital microfluidic chip has a complex structure and a high fabricating cost, while the digital microfluidic chip of the present disclosure has a simple structure, a simple fabricating process and a low fabricating cost, and can realize miniaturization and integration to a maximum extent.

According to one embodiment, an automatic analyzing apparatus includes a liquid tank, a first pump, a dispensing probe, and a thermal exchanger. The liquid tank stores a first liquid. The first pump pressurizes and sends the first liquid supplied from the liquid tank. The dispensing probe uses the first liquid that is sent out from the first pump as a pressure transmitting medium. The thermal exchanger exchanges heat between an atmosphere in the automatic analyzing apparatus and the first liquid in at least a part of a first flow path connecting the first pump to the liquid tank.

The present invention provides devices, systems, and methods for rapid and easy-to-use in sample thermal cycling or temperature changes for the facilitation of reactions such as but not limited to PCR.