B01L2300/1883

Histological Apparatuses for Histological Samples with Humidity Control Lid and Thermal Cover Having Intermittent Access
20240091777 · 2024-03-21 · ·

A histological container for histological samples is provided with a removable humidity control lid with portals for access into the container. The lid creates a humidified zone across the lid portals to allow processing steps inside the container while minimizing variations in the container humidity. A cover can be placed over the container for thermal control inside the container. The cover includes a top with portals aligned with the lid portals for access through the cover and top to inside the container. The cover can include a shutter slidably interfaced with the top. The shutter can include shutter portals selectively aligned with the top portals. Slidable alignment of the shutter portals with the top portals allows access to inside the container. Slidable nonalignment of the shutter portals with the top portals restricts access, essentially closing the container to control temperature levels and other ambient conditions inside the container.

Test element support

A test element support comprises a heating element for heating a test element for analytical examination of a sample. The heating element comprises a substrate, which is made of at least one substrate material. The substrate comprises at least one active area configured for being heated and at least one non-active area outside the active area. The active and the non-active areas are separated by at least one thermal insulation element. The thermal insulation element has a lower thermal conductivity than the substrate material. The thermal insulation element is fully or partially embedded into the substrate. The test element support further comprises at least one heater. The heater comprises at least one heater substrate and the heater substrate is attached to the substrate, wherein the heater substrate is attached to a back face of the substrate. The back face opposes a front face of the substrate contacting the test element.

PORTABLE DEVICE FOR LAMP PCR
20240058820 · 2024-02-22 ·

Provided is a portable isothermal amplification device for amplifying a nucleic acid using an isothermal amplification method, the device comprising: a tube insertion part into which a PCR tube is to be inserted, which is provided in an upper portion of the portable isothermal amplification device; a cover for covering the tube insertion part; a storage space for accommodating a heating device and a storage space cover for blocking the storage space from an outside, which is provided in a lower portion of the portable isothermal amplification device; and a heat insulator for blocking heat from the outside and a heat-sensing sticker capable of measuring a temperature of heat generated by the heating device, which is provided inside the storage space.

Method and system for temperature monitoring of a biochemical reaction vessel
11896977 · 2024-02-13 · ·

Embodiments include a reaction vessel having a first reaction chamber filled with a first material; a first light absorbing region adhered to an interior-facing surface of the first reaction chamber; a second reaction chamber filled with a second material; a second light absorbing region adhered to an interior-facing surface of the second reaction chamber; a temperature sensor disposed within the second reaction chamber; and one or more energy sources configured to direct light at the first light absorbing region and the second light absorbing region. A processor may be employed to determine a first temperature of the first material from a second temperature of the second material measured by the temperature sensor. Methods of manufacturing such a reaction vessel are also disclosed.

THERMAL MANAGEMENT SYSTEM

A thermal management system comprising: a thermal source of low to cryogenic temperature; a heating element for heating the source; a shield adapted to exchange heat by conduction to/from a sample and to/from the source; a controller calibrated for maintaining a gradient of temperature along the shield within a pre-determined range; a vacuum sealing feedthrough comprising a thermal insulator element, the vacuum sealing feedthrough delimiting around the first interface a vacuum sealed volume so that the shield exchanges heat with the thermal source exclusively by conduction and exclusively at a first interface. An exemplary purpose for this thermal management system is the sublimation of water ice and/or water ice trapped in a regolith, and positioned in a vacuum chamber. The heat insulator element is configured to separate physically the thermal source from a vacuum chamber into which the shield can protrude, so that sublimated compounds from the sample do not encounter colder point which would cause their deposition on the shield or on the walls of the chamber.

Automatic Analyzer and Method of Storing Reagent in Automatic Analyzer
20240042448 · 2024-02-08 ·

There is provided an automatic analyzer and a method of storing reagents in an automatic analyzer, in which restrictions on installation of reagent packs are smaller than those of the device in the related art. The automatic analyzer includes a reagent storage 105 that stores reagent packs 201, 301 containing reagents. The reagent storage 105 includes: a first holding unit 403 capable of holding only an immune reagent pack 201 containing a first reagent among the reagents; a second holding unit 404 capable of holding only a biochemical reagent pack 301 containing a second reagent that is different from the first reagent; and a third holding unit 405 capable of holding both the immune reagent pack 201 and the biochemical reagent pack 301.

GENE DETECTION METHOD, GENE DETECTION KIT AND GENE DETECTION DEVICE

A gene detection method, a gene detection kit, and a gene detection device, including the following steps: providing a plurality of separation cavities on a kit, using a plunger to separate adjacent separation cavities, and respectively providing a lysate solution, a washing solution and a reaction solution in the separation cavities; when detecting a sample, pushing each plunger to align a plunger hole of the plunger with the separation cavity, thereby making the separation cavities interconnected; then, controlling magnetic beads in the kit to drive the sample to be tested to pass through the separation cavities in sequence by an electromagnetic control method, carrying out a lysing, a washing and a reaction in sequence; and finally, performing a optical detection on a gene in the reaction solution from outside.

AUTOMATIC ANALYSIS DEVICE

Temperature uniformity of a reaction liquid in a plurality of reaction containers of an automatic analysis device is maintained by a heat block. A strip-shaped heater heats the heat block, and is wound and attached on an outer circumference of the heat block so that both end regions of the strip-shaped heater are adjacent to each other. The strip-shaped heater includes a heat generating resistor that is heated by applying an electric current, an insulating film sandwiching the heat generating resistor, and first and second electrical feed lines that are attached to both end portions of the heat generating resistor and supply power to the heat generating resistor. The width of the heat generating resistor in both end regions of the strip-shaped heater is formed to be narrower than the width of the heat generating resistor in the other region thereof.

BIOLOGIC SAMPLE PREPARATION SYSTEM AND RELATED METHOD

A biologic sample preparation system that prepares samples for processing includes a frame defining a horizontal plane, a pipette assembly, a sample module and an extraction module. The pipette assembly includes a first pipette. The pipette assembly is movably mounted to the frame in a direction substantially perpendicular to the horizontal plane during operation. The sample module includes a sample plate and is movably mounted to the frame. The sample module is movable substantially parallel to the horizontal plane at least from a sample area spaced from the pipette assembly and a working area proximate the pipette assembly. The extraction module includes an extraction plate and is movably mounted to the frame. The extraction module is movable substantially parallel to the horizontal plane at least from an extraction staging area spaced from the pipette, assembly and the working area proximate the pipette assembly.

Sample storage and retrieval system

A sample storage including a frame and an array of sample container holding areas disposed within the frame where a spacing between adjacent sample container holding areas is independent of a gripping area for sample containers held by the sample storage.