Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.

Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.

An immunoblotting instrument and a control method are provided. The immunoblotting instrument comprises an immunoblotting instrument body, and an immunoblotting instrument control device, an incubation device and a liquid feeding and sucking device that are provided on the immunoblotting instrument body, and further comprises a temperature control device for controlling the incubation environment temperature of the immunoblotting membrane. By setting the temperature control device in the immunoblotting instrument to control the temperature of the reaction environment between the immunoblotting membrane and the reagent, the immunoblotting membrane can contact and react with the reagent under the same and set environmental condition, so that the reliability of the final detection results can be improved; at the same time, each functional module is associated and controlled by the control device, so that the entire immunoblotting process is automatically completed, reducing manual intervention and improving work efficiency.

Provided are methods and systems useful for screening large libraries of effector molecules. Such methods and systems are particularly useful in microfluidic systems and devices. The methods and systems provided herein utilize encoded effectors to screen large libraries of effectors.

A microfluidic chip that can have a body defining a microfluidic network including a test volume, one or more ports, and one or more channels in fluid communication between the port(s) and the test volume. Gas can be removed from the test volume before a sample liquid is introduced therein by reducing pressure at a first one of the port(s), optionally while the liquid is disposed in the port. Liquid in the first port can be introduced into the test volume by increasing pressure at the first port. The microfluidic network can define one or more droplet-generating regions in which at least one of the channel(s) defines a constriction and/or two or more of the channels connect at a junction. Liquid flowing from the first port can pass through at least one of the droplet-generating region(s) and to the test volume.

An apparatus (1) for ex-vivo measurement of performance of a donor heart (2) has a heart holder (6) in a receptacle (7) for holding a human donor heart and a bag (17) for placement into a left ventricle of the heart. The bag has a bag interior space communicating with an interior space of a fluid tight, compressible and expandable container (19. The apparatus further includes a sensor (21) for measuring compression and expansion of the container. Using the apparatus cardiac outwit can be measured by measuring expansion and contraction of the container. A method for ex-vivo measurement of performance of a donor heart is also described. The method may include controlling the preload and/or the afterload.

The present disclosure provides a method of separating cellular particles from a tissue sample and then sorting the cellular particles into two or more cellular particle populations.

The present invention relates to systems and methods for manipulating droplets within a high through put microfluidic system.

Described are platforms, systems, media, and methods for maintaining a database of items associated with one or more skill requirements and a visit duration; maintaining a database of experts associated with one or more skill proficiencies, a location, and a schedule; receiving a request from a consumer for delivery by an expert of one or more items in the database to a consumer address; identifying experts in the database having skill proficiencies matching the skill requirements of the one or more items and available in a timeslot for the visit duration of the one or more items; presenting timeslots for which one or more experts are identified to the consumer and allowing the consumer to select a timeslot; and selecting an expert from among the identified experts in the selected timeslot based on shortest travel time; provided that utilization of the selected expert exceeds a predetermined utilization threshold.

A system includes a fluid transfer device and a lateral flow assay device. The fluid transfer device has an inlet fluidically coupleable to a bodily fluid source, an outlet fluidically coupleable to a sample reservoir, and a sequestration chamber configured to receive an initial volume of bodily fluid. The fluid transfer device can be transitioned between (1) a first state with the sequestration chamber in fluid communication with the inlet to receive the initial volume, (2) a second state with the outlet in fluid communication with the inlet to receive a subsequent flow of bodily fluid, and (3) a third state with the lateral flow assay device in fluid communication with the sequestration chamber to receive a portion of the initial volume of bodily fluid. The lateral flow assay device configured to provide an indication associated with a presence of a target analyte in the bodily fluid.