B01L2400/0475

FLUID TRANSFER DEVICE, SYSTEM AND METHOD
20200276587 · 2020-09-03 ·

A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.

DEVICES AND METHODS FOR ANALYSIS OF MALE INFERTILITY
20200278284 · 2020-09-03 ·

Provided herein are devices and methods for analysis of male fertility. The invention provides self-contained, hand-held receptacles and systems for collection and analysis of semen samples and methods of using such devices to analyze semen samples. Also provided are processor-implemented and machine learning methods of analyzing semen sample data obtained using devices of the invention.

Interfacial effects enable droplet actuation, inhibition relief, and early sensing of polymerase chain reaction

Disclosed are devices, systems and methods of use utilizing interfacial effects enabling droplet actuation, inhibition and early sensing of molecular reactions, such as of polymerase chain reaction.

LATERAL FLOW ASSAY DEVICE
20200261905 · 2020-08-20 ·

Lateral flow devices, methods and kits for performing lateral flow assays are provided.

Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method

The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.

Device and Method for Qualitative and Quantitative Analysis of Heavy Metals Utilizing Rotary Disc System

The present invention relates to a device and a method for qualitative and quantitative analysis of heavy metals and more particularly provides a device and a method for qualitative and quantitative analysis of heavy metals utilizing a rotary disc system.

MICROFLUIDIC CHIP AND DRIVING METHOD THEREOF
20200254444 · 2020-08-13 ·

A microfluidic chip and a driving method thereof are provided. The microfluidic chip includes a base substrate, a driving circuit array, a first decoding circuit, and a second decoding circuit, the driving circuit array, the first decoding circuit, and the second decoding circuit are all integrated on the base substrate; the first decoding circuit is configured to generate and output a target scan driving signal to the driving circuit array; the second decoding circuit is configured to generate and output a target driving voltage signal to the driving circuit array; and the driving circuit array is configured to control an operation of a liquid droplet over the driving circuit array based on the target scan driving signal and the target driving voltage signal.

Fluidic peristaltic layer pump
10737264 · 2020-08-11 ·

A microfluidic device is provided for managing fluid flow in disposable assay devices, which provides constant flow even at very low flow rates. Pumps utilizing the microfluidic device, as well as methods for manufacture and performing a microfluidic process are also provided.

Lateral flow assay with controlled conjugate time and controlled flow time
10739297 · 2020-08-11 · ·

A lateral flow assay device comprising a conjugate pad for receiving a quantity of fluid; and a membrane comprising a test line for determining whether the fluid comprises a target analyte. In a first state of the lateral flow assay device, the lateral flow assay device is configured with a removable gap between the conjugate pad and the membrane which is substantially filled with air and prevents the fluid from flowing from the conjugate pad into the membrane. In a second state of the lateral flow assay device, the removable gap is removed from between the conjugate pad and the membrane causing the conjugate pad to come in contact with the membrane, allowing the fluid to flow from the conjugate pad into the membrane and the test line by capillary action.

METHOD AND SYSTEM FOR OPTOFLUIDIC STRETCHING OF BIOLOGICAL CELLS AND SOFT PARTICLES
20200230602 · 2020-07-23 ·

A method for stretching a plurality of sample isolates, including: trapping the plurality of sample isolates away from a wall of at least one microfluidic channel of a microfluidic flow system; generating a microfluidic flow to stretch the plurality of trapped sample isolates; determining deformation characteristics of the plurality of stretched samples isolates based on one or more frames from an image processing system; and outputting information corresponding to the deformation characteristics.