A microfluidic product utilizing gradient surface energy coatings for fluid control comprising a plurality of fluid passages wherein at least one fluid passage comprises a coating configured to control liquid flow wherein the coating configured to control liquid flow comprises a gradient surface energy coating from a proximal location to a distal location on a surface of the fluid passage. The product can include uniform regions and surface gradient regions in the same passage. Coating compositions and product dimensions can be selected to provide control over different flow properties including fluid velocity, reduction and acceleration of fluid flow, and starting and stopping fluid flow.

A digital microfluidic chip, a method for driving the same, and a digital microfluidic device are provided. The digital microfluidic chip includes a state transition layer configured to bear a droplet, and a light driving layer configured to provide light for controlling a lyophobicity-lyophobicity transition of the state transition layer to drive the droplet to move. The light driving layer includes light emitting units arranged in an array and provides light. The state transition layer realizes a lyophobicity-lyophobicity transition. The light driving layer controls the lyophobicity-lyophobicity transition by providing light to drive the droplet to move. An existing digital microfluidic chip has a complex structure and a high fabricating cost, while the digital microfluidic chip of the present disclosure has a simple structure, a simple fabricating process and a low fabricating cost, and can realize miniaturization and integration to a maximum extent.

A microfluidic product utilizing gradient surface energy coatings for fluid control comprising a plurality of fluid passages wherein at least one fluid passage comprises a coating configured to control liquid flow wherein the coating configured to control liquid flow comprises a gradient surface energy coating from a proximal location to a distal location on a surface of the fluid passage. The product can include uniform regions and surface gradient regions in the same passage. Coating compositions and product dimensions can be selected to provide control over different flow properties including fluid velocity, reduction and acceleration of fluid flow, and starting and stopping fluid flow.

A microfluidic device for performing physical, chemical or biological treatment to at least one packet without contamination.

A microfluidic device for performing physical, chemical or biological treatment to at least one packet without contamination.

A biological sample collection device can include a sample collection vessel having a sample collection chamber with an opening configured to receive a biological sample into the sample collection chamber. The sample collection chamber can also include elongate ridges disposed along and projecting inwardly from an interior portion thereof. The sample collection vessel can also include a connection member disposed on an exterior portion and a fluid reservoir. The fluid reservoir can include a reagent chamber having an open end and a closed end with an elongate member disposed at the closed end that is sized and shaped to engage the elongate ridges of the sample collection vessel when arranged within the fluid reservoir. The sample collection vessel can also include a sealing cap having internal threads for engaging external threads of the fluid reservoir and a complementary connection member to couple the sample collection vessel and the sealing cap.

A microfluidic product utilizing gradient surface energy coatings for fluid control comprising a plurality of fluid passages wherein at least one fluid passage comprises a coating configured to control liquid flow wherein the coating configured to control liquid flow comprises a gradient surface energy coating from a proximal location to a distal location on a surface of the fluid passage. The product can include uniform regions and surface gradient regions in the same passage. Coating compositions and product dimensions can be selected to provide control over different flow properties including fluid velocity, reduction and acceleration of fluid flow, and starting and stopping fluid flow.

An objective is to provide a fluid handling device capable of reliably generating a dispersion liquid in which a liquid droplet containing a sample is dispersed in a dispersion medium. The fluid handling device achieving the objective includes: a sample channel; a dispersion medium channel; a dispersion liquid generation part connected to the sample channel and the dispersion medium channel, and configured to divide the sample by the dispersion medium to generate a dispersion liquid in which a liquid droplet of the sample is dispersed in the dispersion medium; and a dispersion liquid channel connected to the dispersion liquid generation part, in which Y?0.0436X?1.2563 is satisfied, where X denotes a contact angle [?] between a portion of an inner wall of the dispersion liquid channel and water, and Y denotes a viscosity [mPa.Math.s] of the sample measured at 25? C. by a falling-ball viscometer.

A micropump includes a body with an inlet and an outlet defined therein. A channel connects the inlet to the outlet. The micropump further includes a magnetic shape memory (MSM) alloy positioned within the channel. The MSM alloy selectively forms a barrier between the inlet and the outlet. The micropump also includes an electrode and/or a transparent window positioned along a surface of the channel. A cavity is selectively formed within a surface of the MSM alloy due to a magnetic field. The cavity is selectively moveable between a first position adjacent to the inlet, a second position adjacent to the electrode and/or the transparent window, and a third position adjacent to the outlet, by altering the magnetic field. By altering a magnetic field applied to the MSM alloy, a fluid may be pumped from the inlet to the electrode and/or the transparent window where the fluid may be analyzed. The fluid may be subsequently pumped to the outlet.

In accordance with some embodiments of the present disclosure, a loading tool for a multi-well chromatography filter plate is disclosed. The loading tool may include a top plate and a bottom plate slidably coupled to the top plate. The top plate may include a plurality of wells for holding a material, a rail located along a side of the top plate, and a notch formed in the rail. The bottom plate may include a plurality of funnels extending from the bottom plate, each of the plurality of funnels corresponding to one of the plurality of wells, a track located along a side of the bottom plate to receive the rail located on the top plate, and a pathway formed in the track to receive the notch such that the notch and the pathway limit movement of the top plate relative to the bottom plate.