A reaction cuvette according to an embodiment is used for measurement performed by an automatic analyzing device, and is a reaction cuvette that houses a mixed liquid of a reagent and a sample to be measured. The reaction cuvette includes a cuvette main body and an aspiration port. The aspiration port is disposed on the cuvette main body, and allows a fluid to flow into an inner part of the cuvette main body from a bottom surface side of the cuvette main body.

Provided are a reaction well cartridge device and reaction well cartridge system suitable for biochemical or biological reaction, the reaction well cartridge device including a cartridge body including at least one of a reaction well container containing a reaction well where biological reactions occur, pipette tip containers containing at least pipette tips, a sample container containing a sample, reagent containers containing reagents, a mixed solution container containing a mixed solution of the sample and the reagents, a diluent container containing a diluent, washing solution containers containing washing solutions, and combinations thereof, and a temporary storage provided on the cartridge body to temporarily store wastes produced after the reactions occur in the reaction well.

A washing device comprises a manifold dispenser comprising at least one liquid input and a plurality of liquid outputs that operably direct fluid to contact a plurality of laboratory consumables held by a rack in the washing device, an ultra-violet (UV) light source, and a plurality of fiber optic channels coupled to the UV light source, each of the fiber optic channels extending into a corresponding one of the liquid outputs. The plurality of liquid outputs may each comprise a nozzle having an opening into which a respective one of the plurality of fiber optic channels extends.

The present invention provides an automated system and method to isolate nucleated blood cells from whole blood or bone marrow. A disc mounted to a centrifuge system with spinning rotor is used to manipulate cells by channeling fluids while subjected to high gravitational field. The disc embodies at least two axisymmetric processing stations connected by a circular channel. Each station contains multiple chambers connected by fluidic channels to controllably transfer fluids. First stage separation allows for the isolation of the buffy coat layer while the second stage separation utilizes gradient density fluids to isolate the targeted nucleated cells from the buffy coat layer in the spinning disc.

A testing device (20, 120, 220, 290, 320, 420, 520, 620, 720, 820, 1020, 1120) is provided for testing for the presence of particulate in a liquid (22). The testing device (20, 120, 220, 290, 320, 420, 520, 620, 720, 820, 1020, 1120) includes a liquid container (30, 730) for containing the liquid (22); a filter (32, 132, 732), disposed in or downstream of the liquid container (30, 730); a liquid-pressure source (34, 734), which is arranged to apply pressure to drive the liquid (22) contained in the liquid container (30, 730) through the filter (32, 132, 732); and a filter chamber (36, 136, 236, 336, 736) that is (a) disposed downstream of the liquid container (30, 730), (b) shaped so as to define an inlet (38, 138, 238, 738, 838), and (c) in fluid communication with the filter (32, 132, 732). Other embodiments are also described.

The microfluidic board comprises a plurality of matrix units, wherein each matrix unit is a stacked arrangement comprising a driving portion comprising an actuator, a pump portion in contact with the driving portion and comprising a pump, a channel portion in contact with the pump portion and comprising one or more channels, and a chamber portion in contact with the channel portion and comprising a chamber, wherein the one or more channels are configured to direct fluid between the pump and the chamber, and wherein the actuator is configured to generate a force to drive the pump upon receiving of an input energy.

An acoustic analyzer system is provided that includes an acoustic analyzer having a reusable glass flow cell positioned within the acoustic analyzer. A disposable card body may be inserted into the acoustic analyzer and deliver sample fluid to the glass flow cell so that acoustic-wave assisted measurements may be performed on the sample fluid. The disposable card body may also deliver wash fluid to the glass flow cell, and receive waste sample fluid and waste wash fluid from the glass flow cell to prepare the glass flow cell for subsequent sample fluids. Numerous other embodiments are provided.

A body fluid component separating device according to an embodiment may comprise: a housing; a piston which divides the housing into a first space and a second space and connects the first space and the second space via fluid-connection; and a manipulator which is coupled to the piston to be operable and is configured to maintain a pressure balance between the first space and the second space, adjust movement of the piston between a first location at which the first space has a first volume and a second location at which the first space has a second volume that is different from the first volume, and fix the piston on an arbitrary location between the first location and the second location.

The present disclosure relates to a microfluidic immunoassay chip and a microfluidic line immunoassay method. The microfluidic immunoassay chip includes a loading cell, a reaction and detection cell, a washing cell, an enzyme storing cell, a substrate cell, and a termination cell, and a waste liquid cell. A detection membrane strip is disposed in the reaction and detection cell and coated with a capture antigen or a capture antibody.

Methods and systems for online sampling an aliquot from a mobile phase comprising an analyte for producing a pharmaceutical or chemical product, wherein the apparatus comprises an analytical device and a tube between an inlet and an outlet, wherein the outlet is in fluid communication with the analytical device, the method comprising: providing a sample device comprising a needle with a needle tip, a septum pierceable by the needle and a pump, wherein the needle is moveable between an extended position in which the septum is pierced by the needle, and a retracted position, in which the septum is not pierced, disposing the sample device at the curved portion of the tube, moving the needle to the extended position such that the needle tip faces the flow direction, and drawing out an aliquot out of the mobile phase.