There is provided a cartridge for nucleic acid extraction comprising: a first body having a plurality of chambers in which ports are formed at the bottom; a second body coupled to a lower region of the first body; and a piston disposed rotatably in the centers of the first body and the second body and having a port formed at the bottom thereof; and characterized in that the cartridge comprises a plurality of flow paths formed on the upper region of the second body, one end overlapping the port of the piston and the other end overlapping the port of the first body.

The invention provides integrated Organ-on-Chip microphysiological systems representations of living Organs and support structures for such microphysiological systems.

The present disclosure is drawn to devices and systems for target detection in samples, particularly allergen detection in food samples. The allergen detection system includes a sampler, a disposable analysis cartridge and a detection device with an optimized optical system. The allergen detection utilizes nucleic acid molecules as detection agents and detection probes.

There are provided a blood examination kit with which the procedure carried out by an examination subject is simplified and a method of separating plasma or serum. The blood examination kit includes a blood collection instrument including a diluent and a first container that has an opening formed on one end side and accommodates the diluent; an absorption instrument including a first lid portion member that is arranged on one end side and can seal the opening of the first container, and an absorption member that is arranged on the other end side and absorbs a blood sample; and a separation and sealing instrument including a filtration member that separates plasma or serum from the blood sample diluted with the diluent, a second container that holds the filtration member on the other end side, accommodates the separated plasma or serum, and can be inserted into the first container, a second lid portion member that is arranged on one end side of the second container and can seal the opening of the first container, and a valve member that closes a flow channel between the first container and the second container.

An infectious disease screening system (1) for screening for infectious diseases, such as COVID-19 disease. The system comprises an ultrasonic transducer (49) for generating ultrasonic waves to lyse cells in a biological sample. The system (1) comprises a controller which controls the ultrasonic transducer (49) to oscillate at an optimum frequency for cell lysis, a PCR apparatus (16) which receives and amplifies the DNA from the sample; and a detection apparatus (70) which detects the presence of an infectious disease in the amplified DNA and provides an output which is indicative of whether or not the detection arrangement (70) detects the presence of an infectious disease in the amplified DNA.

An analysis system may perform operations on an analyte that may be combined with multiple regents prior to being introduced into a flow cell. The instrument may include a volume into which the reagents to be combined with the analyte are aspirated one-by-one. The volume may be formed as a serpentine channel in a valve manifold associated with sippers for aspirating the reagents. The reagents may then be mixed by cycling a pump to move the reagents within the mixing volume or channel. For this, the reagents may be aspirated from a recipient into the volume or channel, ejected back into the recipient, and this process may be performed repeatedly to enhance mixing.

Automated microfluidic systems and methods are described for purifying, extracting, and optionally analyzing magnetic target entities such as cells, e.g., bound to one or more magnetic beads.

An immunoblotting instrument and a control method are provided. The immunoblotting instrument comprises an immunoblotting instrument body, and an immunoblotting instrument control device, an incubation device and a liquid feeding and sucking device that are provided on the immunoblotting instrument body, and further comprises a temperature control device for controlling the incubation environment temperature of the immunoblotting membrane. By setting the temperature control device in the immunoblotting instrument to control the temperature of the reaction environment between the immunoblotting membrane and the reagent, the immunoblotting membrane can contact and react with the reagent under the same and set environmental condition, so that the reliability of the final detection results can be improved; at the same time, each functional module is associated and controlled by the control device, so that the entire immunoblotting process is automatically completed, reducing manual intervention and improving work efficiency.

Embodiments of the present invention relate to microfluidic devices and systems comprising such devices for use in the determination of sample characteristics. Certain embodiments relate to methods for determining one or more characteristics of a sample comprising a compound for in vivo use. Aptly, certain embodiments of the present invention relate to devices and methods for assessing radiopharmaceuticals and their suitability for administration to a patient in need thereof.

The present invention aims at providing a fluidic device that can hold a large amount of solutions in a reservoir without depending on an attitude. The reservoir includes a meandering flow path including: a plurality of first flow paths that extend linearly along a first direction and that are arranged to be spaced in a second direction crossing the first direction; and a second flow path that extends linearly along the second direction such that a connection between first end sides of the adjacent first flow paths and a connection between second end sides of the adjacent first flow paths are alternately switched along the second direction for each first flow path, wherein the meandering flow path meanders along the second direction. When the length of each of the first flow path and the second flow path is L, a surface tension is γ, the density of the solution is ρ, the acceleration which includes a gravity and which is applied to the solution is G, the wetted perimeter length of the first flow path and the second flow path is Wp, a cross-sectional area of the first flow path and the second flow path is A, a receding contact angle is α, and an advancing contact angle is β, a relationship L≤(γ×Wp×(cos α−cos β))/(ρ×A×G) is satisfied.