An apparatus and method for isolating bacterial particles in a sample using a container with material in temporary fluid blocking position to lower orifice in the container, a separation medium having an electrical conductivity lower than and physical density greater than that of the sample above the material that supports a sample concentrate after passing through the separation medium when exposed to centrifugal force, a heating element for liquefying the material to permit flow into a chamber past an electrode array that attracts and holds subject particles. The system allows rapid detection and isolation of particles from samples from animal, human, environmental sites, a bio-industrial reactor or a food or beverage production facility requiring relatively small volumes, short incubation times resulting in structurally intact particles for further analysis. Testing may be completed in a single unit that requires decreased technician manipulation, fewer steps and a decrease in cross-contamination.

A chip includes a first chamber that stores a fluid, a second chamber that stores a mixing target which is to be mixed with the fluid, a flow path that allows a communication between the first chamber and the second chamber, and a valve that is provided in the flow path and capable of changing the flow path by change in shape by heating.

The technology described herein generally relates to microfluidic cartridges configured to amplify and detect polynucleotides extracted from multiple biological samples in parallel. The technology includes a microfluidic substrate, comprising: a plurality of sample lanes, wherein each of the plurality of sample lanes comprises a microfluidic network having, in fluid communication with one another: an inlet; a first valve and a second valve; a first channel leading from the inlet, via the first valve, to a reaction chamber; and a second channel leading from the reaction chamber, via the second valve, to a vent.

A method for inserting and retaining a reagent within a disposable cartridge of a diagnostic assay system. The method includes the steps of: (i) drying a reagent in combination with a carrier, and (ii) inserting the carrier, with the dried reagent, into an open end of one of the assay chambers, wherein the carrier facilitates insertion of the pellet into a chamber without contact by an operator.

Systems, methods, and apparatus are provided for evacuating and for filling an array at the point of use.

A microfluidic device for detection of an analyte in a fluid is described. The microfluidic device comprises a substrate having a first surface defining entrances to one or more chambers defined in the substrate, surfaces of the chambers defining a second surface of the substrate, the first surface being modified for selective targeting and capture of at least one analyte to operably effect a blocking of the entrance to at least one of the chambers, and wherein a response characteristic of the microfluidic device is operably varied by the blocking of the entrance to the at least one of the chambers, thereby providing an indication of the presence of the analyte within the fluid.

A microfluidic chip and a detection system. The microfluidic chip comprises fluid inlet channels (21) and a microvalve (1), and the microvalve (1) comprises a magnetic valve core (12), a valve core movement channel (11) and a magnetic control device (13); the valve core movement channel (11) is provided with at least two adapter openings (111), and at least one adapter opening (111) is connected to the fluid inlet channels (21); the magnetic valve core (12) is located in the valve core movement channel (11) and may move in the valve core movement channel (11), and the radial size of the magnetic valve core (12) is greater than that of each adapter opening (111); and the magnetic control device (13) is located outside the valve core movement channel (11), and is configured to move along the valve core movement channel (11) so as to drive the magnetic valve core (12) to move in the valve core movement channel (11).

The invention discloses a highly integrated analyte detection system, including: a bottom case; a sensor structure, the sensor structure includes a sensor and a sensor base, the sensor includes a signal output end and a detection end, and at least two first electrical connection areas insulated from each other are provided on the surface of the signal output end; and a transmitter, the transmitter and the bottom case are fastened with each other, and the transmitter is provided with second electrical connection areas, which are insulated from each other, corresponding to the first electrical connection areas, each second electrical connection area is electrically connected to the corresponding first electrical connection area. Such a design reduces the height of the sensor structure, making the overall structure of the detection system more compact, as a result, reducing the volume and enhancing the user experience.

The invention discloses a micro-analyte detection device, which comprises a bottom case, the bottom board of the bottom case is provided with a mounting hole; a sensor structure, the sensor structure includes a sensor and a sensor base, and the sensor includes a signal output end and a detection end, and a transmitter, the transmitter includes a transmitter housing and an electronic device, the electronic device is provided with an electrical connection area, when the transmitter is installed in the working position, the electrical connection area is electrically connected with the signal output end. This device effectively reduces the overall thickness of the analyte detection device and enhances the user experience.

A sensing device includes a base, a probe structure and a transmitter structure. The base is provided with a first fastener part. The probe structure includes a second fastener part, a probe and a connection area. The transmitter structure includes a transmitter housing and a transmitter disposed inside the transmitter housing, the transmitter housing is provided with a connection hole, the shape of which matches the shape of the probe structure, and when the transmitter structure is mounted to the base, the probe structure is located in the connection hole, and the transmitter is electrically connected to the connection area to receive the signal generated by the probe.