The present invention relates to methods for producing nanoparticle and microparticle powders of a biologically active material which have improved powder handling properties making the powders suitable for commercial use using dry milling processes as well as compositions comprising such materials, medicaments produced using said biologically active materials in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of said biologically active materials administered by way of said medicaments.

The present invention relates to methods for producing nanoparticle and microparticle powders of a biologically active material which have improved powder handling properties making the powders suitable for commercial use using dry milling processes as well as compositions comprising such materials, medicaments produced using said biologically active materials in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of said biologically active materials administered by way of said medicaments.

The present invention provides a grinding and shaping method using a vertical grinding mill. The grinding and shaping method comprises selecting a vertical grinding mill with thread pitch/diameter ratio of a spiral rotor; selecting the grade of a grinding medium and determining a filling factor and adding the grinding medium into a grinding chamber of the vertical grinding mill; sequentially initiating a dust collector, an air blowing device, a driving device and a feeding device; adjusting rotation speed of the spiral rotor; feeding a raw material into the feeding port at an upper end of the grinding chamber; initiating a discharging device, and discharging the raw material from a discharging port; wherein when selecting the vertical grinding mill, the thread pitch/diameter ratio of the spiral rotor is determined according to the Mohs hardness of the raw material.

The mill apparatus comprises: a container to which a discharge pipe is connected; a mill mechanism that is arranged in the container and pulverizes powder; a gas feeding mechanism that has a function of feeding a gas into the container; and a wing mechanism for adjusting an amount of gas discharged from the discharge pipe. The wing mechanism has a plurality of wings arranged point-symmetrically with an axis. The amount of gas discharged from the discharge pipe is adjusted by changing a gap between two wings adjacent to each other of the plurality of wings.

The mill apparatus comprises: a container to which a discharge pipe is connected; a mill mechanism that is arranged in the container and pulverizes powder; a gas feeding mechanism that has a function of feeding a gas into the container; and a wing mechanism for adjusting an amount of gas discharged from the discharge pipe. The wing mechanism has a plurality of wings arranged point-symmetrically with an axis. The amount of gas discharged from the discharge pipe is adjusted by changing a gap between two wings adjacent to each other of the plurality of wings.

Embodiments described herein relate generally to large scale synthesis of thinned graphite and in particular, few layers of graphene sheets and graphene-graphite composites. In some embodiments, a method for producing thinned crystalline graphite from precursor crystalline graphite using wet ball milling processes is disclosed herein. The method includes transferring crystalline graphite into a ball milling vessel that includes a grinding media. A first and a second solvent are transferred into the ball milling vessel and the ball milling vessel is rotated to cause the shearing of layers of the crystalline graphite to produce thinned crystalline graphite.

The disclosed subject matter provides methods using and kits comprising a compound of formula (I)

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or a pharmaceutically acceptable salt thereof.

A silicon material can include a silicon aggregate comprising a plurality of porous silicon nanoparticles welded together. The silicon aggregate can optionally have a polyhedral morphology. A method can include: receiving a plurality of porous silicon nanoparticles and cold welding the plurality of porous silicon nanoparticles into an aggregated silicon particle.

A silicon material can include a silicon aggregate comprising a plurality of porous silicon nanoparticles welded together. The silicon aggregate can optionally have a polyhedral morphology. A method can include: receiving a plurality of porous silicon nanoparticles and cold welding the plurality of porous silicon nanoparticles into an aggregated silicon particle.

A method and system for magnetic actuated mixing which use magnetic particles, non-magnetic abrasive particles and electromagnetic field to facilitate milling. The method and system use magnetic particles and a generated electromagnetic field to facilitate the milling as well. The method and system can be used in any application that requires the preparation of small-sized particles at either the micro or nano scale, including for example, preparing toners, inks, wax, pigment dispersions and the like.