B04B1/12

OUTLET NOZZLE FOR A CENTRIFUGAL DRUM, CENTRIFUGAL DRUM AND ASSEMBLY TOOL
20210178407 · 2021-06-17 ·

An outlet nozzle for centrifugal drums has a nozzle body with at least one cylindrical portion and having an insert connected to the nozzle body. An inlet channel and an outlet channel, which is oriented at an angle with respect to the inlet channel, are formed in the nozzle body. The insert has a torque transmitting contour for arranging a tool with a complementary tool torque transmitting contour in position in order to rotatingly secure the nozzle body in an opening of a rotatable centrifugal drum and to release said nozzle body. The insert also has a polygonal cross-section, which is smaller than the cross-section of the cylindrical section. The insert starting from the polygonal, in particular, rectangular cross-section, merges with the cylindrical section of the nozzle body over rounded surfaces having a radius greater than 1.0 mm.

OUTLET NOZZLE FOR A CENTRIFUGAL DRUM, CENTRIFUGAL DRUM AND ASSEMBLY TOOL
20210178407 · 2021-06-17 ·

An outlet nozzle for centrifugal drums has a nozzle body with at least one cylindrical portion and having an insert connected to the nozzle body. An inlet channel and an outlet channel, which is oriented at an angle with respect to the inlet channel, are formed in the nozzle body. The insert has a torque transmitting contour for arranging a tool with a complementary tool torque transmitting contour in position in order to rotatingly secure the nozzle body in an opening of a rotatable centrifugal drum and to release said nozzle body. The insert also has a polygonal cross-section, which is smaller than the cross-section of the cylindrical section. The insert starting from the polygonal, in particular, rectangular cross-section, merges with the cylindrical section of the nozzle body over rounded surfaces having a radius greater than 1.0 mm.

Outlet nozzle for a centrifugal drum, centrifugal drum and assembly tool

An outlet nozzle for centrifugal drums has a nozzle body with at least one cylindrical portion and having an insert connected to the nozzle body. An inlet channel and an outlet channel, which is oriented at an angle with respect to the inlet channel, are formed in the nozzle body. The insert has a torque transmitting contour for arranging a tool with a complementary tool torque transmitting contour in position in order to rotatingly secure the nozzle body in an opening of a rotatable centrifugal drum and to release said nozzle body. The insert also has a polygonal cross-section, which is smaller than the cross-section of the cylindrical section. The insert starting from the polygonal, in particular, rectangular cross-section, merges with the cylindrical section of the nozzle body over rounded surfaces having a radius greater than 1.0 mm.

Outlet nozzle for a centrifugal drum, centrifugal drum and assembly tool

An outlet nozzle for centrifugal drums has a nozzle body with at least one cylindrical portion and having an insert connected to the nozzle body. An inlet channel and an outlet channel, which is oriented at an angle with respect to the inlet channel, are formed in the nozzle body. The insert has a torque transmitting contour for arranging a tool with a complementary tool torque transmitting contour in position in order to rotatingly secure the nozzle body in an opening of a rotatable centrifugal drum and to release said nozzle body. The insert also has a polygonal cross-section, which is smaller than the cross-section of the cylindrical section. The insert starting from the polygonal, in particular, rectangular cross-section, merges with the cylindrical section of the nozzle body over rounded surfaces having a radius greater than 1.0 mm.

Apparatus with axially movable wall member for separating components of a fluid stream

A centrifugal separator apparatus for separating components of a fluid stream; the apparatus comprising a support structure and a centrifugal separator unit rotatably mounted on the support structure so as to be rotatable about a rotational axis extending through the centrifugal separator unit; a drive element for driving rotation of the centrifugal separator unit; wherein the centrifugal separator unit comprises a centrifugal separation chamber having an inlet which is connected or connectable to a source of fluid requiring separation, a first outlet for collecting a higher density component of the fluid stream, and a second outlet for collecting a lower density component of the fluid stream; the first outlet being connected or connectable to a first collector for collecting the higher density component and the second outlet being connected or connectable to a second collector for collecting the lower density component; the centrifugal separation chamber comprising a curved or inclined guide surface for guiding flow of the fluid from the inlet in a radially outward direction; wherein the centrifugal separator unit is provided with a wall member which is axially movable to provide a selected degree of occlusion of the first outlet and thereby control flow of the higher density component through the first outlet.

Apparatus with axially movable wall member for separating components of a fluid stream

A centrifugal separator apparatus for separating components of a fluid stream; the apparatus comprising a support structure and a centrifugal separator unit rotatably mounted on the support structure so as to be rotatable about a rotational axis extending through the centrifugal separator unit; a drive element for driving rotation of the centrifugal separator unit; wherein the centrifugal separator unit comprises a centrifugal separation chamber having an inlet which is connected or connectable to a source of fluid requiring separation, a first outlet for collecting a higher density component of the fluid stream, and a second outlet for collecting a lower density component of the fluid stream; the first outlet being connected or connectable to a first collector for collecting the higher density component and the second outlet being connected or connectable to a second collector for collecting the lower density component; the centrifugal separation chamber comprising a curved or inclined guide surface for guiding flow of the fluid from the inlet in a radially outward direction; wherein the centrifugal separator unit is provided with a wall member which is axially movable to provide a selected degree of occlusion of the first outlet and thereby control flow of the higher density component through the first outlet.

Method for citrus fruit processing

The present invention provides a method for citrus fruit processing comprising the steps of introducing liquid citrus fruit material to be processed via an inlet to a centrifugal separator being mechanically hermetically sealed at the inlet and at the liquid outlets; separating the citrus fruit material in the separator to obtain at least a liquid heavy phase and a liquid light phase, wherein the density of the liquid heavy phase is higher than the density of the liquid light phase; discharging the liquid heavy phase via a liquid heavy phase outlet and the liquid light phase via a liquid light phase outlet of the separator; measuring at least one parameter of the discharged liquid heavy phase and/or liquid light phase, wherein the parameter is related to a concentration of the heavy phase in the liquid light phase, or vice versa; and adjusting the counter pressure of the liquid heavy phase outlet with respect to the liquid light phase outlet, or vice versa, based on the measurement in step d) so as to control the concentration of the heavy phase in the liquid light phase, or vice versa, discharged from the separator. The present invention further provides a system for performing the method.

Method for citrus fruit processing

The present invention provides a method for citrus fruit processing comprising the steps of introducing liquid citrus fruit material to be processed via an inlet to a centrifugal separator being mechanically hermetically sealed at the inlet and at the liquid outlets; separating the citrus fruit material in the separator to obtain at least a liquid heavy phase and a liquid light phase, wherein the density of the liquid heavy phase is higher than the density of the liquid light phase; discharging the liquid heavy phase via a liquid heavy phase outlet and the liquid light phase via a liquid light phase outlet of the separator; measuring at least one parameter of the discharged liquid heavy phase and/or liquid light phase, wherein the parameter is related to a concentration of the heavy phase in the liquid light phase, or vice versa; and adjusting the counter pressure of the liquid heavy phase outlet with respect to the liquid light phase outlet, or vice versa, based on the measurement in step d) so as to control the concentration of the heavy phase in the liquid light phase, or vice versa, discharged from the separator. The present invention further provides a system for performing the method.

DEVICE AND PROCEDURE FOR PRODUCING A CELLULAR PHARMACEUTICAL PRODUCT ENRICHED IN TARGET CELLS AT THE BEDSIDE OR IN A SURGICAL ROOM

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

DEVICE AND PROCEDURE FOR PRODUCING A CELLULAR PHARMACEUTICAL PRODUCT ENRICHED IN TARGET CELLS AT THE BEDSIDE OR IN A SURGICAL ROOM

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.