A neuromodulation system for treatment of physiological disorders. The system includes one or more stimulators for stimulating one or more cranial nerves; one or more detectors configured for detecting a predetermined physiological state; and a control unit that controls nerve stimulation by the one or more stimulators so that it is synchronized with the at least one predetermined physiological state detected by the one or more detectors. A method of neuromodulating a patient for treatment of physiological disorder. The method includes the steps of detecting a predetermined physiological state and applying stimulation to one of the cranial nerves during the predetermined physiological state by one or more stimulators of a neuromodulation system.

A wearable rehabilitation device features a wearable support sized and shaped for worn fitting thereof over a body part of a patient, one or more vibratory stimulators on the wearable support that are positioned and operable to stimulate muscle tendon tissue of said body part of the patient, and one or more accelerometers on the wearable support configured to generate output signals responsive to vibration of said one or more vibratory stimulators. A controller compares output signals from the accelerometer against a targeted vibrational frequency, and adjusts operating conditions of the stimulator based on detected disagreement to achieve the targeted frequency for optimal therapeutic effect.

A garment with prepositioned, definite sensory stimulating devices attached. The sensory stimulating devices include, but are not limited to, electrical stimulation, audio and physical stimulation such as localized force generation, compression, constriction, vibration, and surround sound. Predetermined and defined actuators allow the wearer to receive tissue, nerve and/or muscle stimulation and/or contraction so that the stimulation is precise as determined by its ability to conform to the scientific methodology of repeatability, reproducibility and reliability; this being due to consistency of actuator positioning in one or multiple locals on the human body. A personal surround sound can also be integrated to the garment to ensure the wearer is always in the optimal position relative to the speakers. These actuators can be force generators within the garment for the wearer to feel impact or apparatus or electrodes included in the garment to locally constrict and increase pressure to the wearer.

Apparatus and associated methods relate to a wearable compression therapy system for ambulatory therapy, the system including a wearable garment having one or more inflatable chambers, and a pneumatic engine locally coupled to the garment to provide control and inflation of the one or more inflatable chambers. In an illustrative embodiment, the pneumatic engine may control a pump and one or more valves to inflate the inflatable chambers. The valves and pump may be coordinated according to a pre-programmed profile. In some embodiments, the pneumatic engine may have a wireless interface configured to receive control signals from a remote mobile device untethered from the garment. The pneumatic engine may send to the remote mobile device signals indicative of sensed conditions of the compression therapy system. In some embodiments, the pneumatic engine may include a power source that advantageously permits the user to be untethered from a source of power.

A fully wearable system used for communication and information transfer between two users or between a user and a machine to render an effective and intuitive physical interface for combined input and output functions, the fully wearable system including a bidirectional wearable skin including distributed actuator and sensing elements, the actuator and sensing elements including a multimodal actuation layer and a sensing layer, the bidirectional wearable skin being flexible and stretchable, and a portable control device for controlling the distributed actuator and sensing elements, and reading signals from the sensing layer, the portable control device is configured to perform pixilated actuation for both micro- and macrostimulation of a body of a wearer by an actuation frequency and stimulation amplitude.

A walking assist device has a frame, a pair of right and left arm portions, a pair of right and left grasp portions, wheels including a pair of right and left drive wheels, drive units, a battery, a drive control unit, acting force measurement units that measure acting forces on the grasp portions, and holding units that hold the grasp portions at a predetermined position in the front-rear direction of the arm portions set in advance. The walking assist device travels forward together with a user. The holding units generate a restoring force for returning the grasp portions to the predetermined position. The drive control unit controls the drive units on the basis of acting forces calculated on the basis of detection signals from the acting force measurement units.

A system for treating a joint of a patient includes a treatment head including a probe, a force impulse wave sensor, and a pressure sensor. When the probe is pressed against the joint and reaches a predetermined pressure, the pressure sensor causes a release of current such that the probe delivers a mechanical force impulse to the joint. The force impulse wave sensor is configured to sense a frequency of the mechanical force impulse associated with a treatment point of the joint. The treatment head remains in the same target spot during the pre-test, treatment, and post-test. The system is configured to perform the pretest and post-test analysis of the plurality of treatment points to evaluate improvement of the joint after the treatment. The treatment protocol for the treatment point is modified based on the sensed frequency of the mechanical force impulse from the pre-test at the treatment point.

In various embodiments, provided herein are systems, methods, processes, and devices for providing locomotive rehabilitation to a subject via one or more gait motions that substantially accurately mimic motions performed in healthy, natural gait cycles. The system may mimic natural gait motions via footplates and handles, and one or more linkage systems. In particular embodiments, the system may further include a motor unit and/or clutch for providing controlled forces assisting or resisting motions of a linkage system. Further, the system may include a tower for operating in a standing or seated position. In at least one embodiment, the system includes a body weight support system that provides offloading forces to a subject.

An item of clothing is adapted to be worn against the skin, and having at least one panel adapted to provide targeted compression of at least 20% of the total length of a specific surface vein in the body, or adapted to provide targeted compression of at least 20% of a specific plexus of veins, a specific lymphatic plexus, drainage plexus or a collection of lymphatic vessels. The clothing is useful in a method of reducing recovery time in a human or other mammal, after a period of activity and in a method of enhancing performance, in particular sports performance, in a human or other mammal. It may also improve the conditioning of the skin and aid lymphatic drainage, and can be used in the treatment of certain medical conditions.

Embodiments of the present disclosure are directed to methods of inducing therapeutic adipose tissue inflammation using high frequency pressure waves (e.g. high frequency shockwaves) wherein the inflammation results in a reduction in the volume of subcutaneous adipose tissue. Embodiments include applying electrohydraulic generated shockwaves at a rate of between 10 Hz and 1000 Hz to reduce the appearance of cellulite or the volume of subcutaneous fat in a treatment area.