Embodiments relate to devices, systems and methods of assisting blood flow return to the heart from a limb. The device comprising a wearable garment (115) and a compression apparatus (110) embedded in the garment (115) for applying an external compression according to a compression sequence to a muscle of a limb of a user based on real-time measurements regarding a cardiac cycle having a diastolic phase and systolic phase of the user and real-time measurements of muscle activity. The compression sequence is synchronized to commence when both the local blood flow at the limb is in the diastolic phase and the muscle is in a non-contracted state,

The invention relates to a device for driving the lower limbs of a person, including a base frame; a table supporting the person; at least one motorized mechanical orthosis arranged to constitute an interface with at least one of the lower limbs of the person so that the movements of the lower limb and the orthosis are connected and identical and with the orthosis being attached to one end of the table; and a device for functional electrical stimulation and for measuring an electromyogram including at least one pair of stimulation and measurement electrodes intended for acting on a muscle or muscle group of the lower limb, and for stimulating the muscle or muscle group, as well as for measuring the reaction of the muscle or muscle group, wherein the device also includes a raising mechanism which makes it possible to vary the vertical position of the table relative to the base frame between a low position in which the transfer and the installation of the person are made easier, intermediate working positions, and a raised position making it possible to drive the person in a standing position, and a mechanism for tilting the table which makes it possible to vary the inclination of the table relative to the base frame, in particular between a horizontal position in which the person is positioned in dorsal decubitus, and a vertical position in which the person is in a standing position, and wherein the combination of the mechanisms for raising and tilting the table allowing the mobility of the orthosis across the entire respective physiological ranges of movement of the lower limb.

A medical monitoring and treatment device that includes a therapy delivery interface, a plurality of therapy electrodes coupled to the therapy delivery interface, a plurality of electrocardiogram sensing electrodes to sense electrocardiogram signals of a patient, a sensor interface to receive the electrocardiogram signals and digitize the electrocardiogram signals, and at least one processor coupled to the sensor interface and the therapy delivery interface to analyze the digitized electrocardiogram signals, to detect a cardiac arrhythmia based on the digitized electrocardiogram signals, and to control the therapy delivery interface to apply electrical therapy to the patient based upon the detected cardiac arrhythmia. The at least one processor is further configured to analyze a frequency domain transform of the digitized electrocardiogram signals, to determine a metric indicative of a metabolic state of a heart of the patient, and to accelerate or delay application of the electrical therapy based upon the metric.

The invention relates to a method and an apparatus for electrical stimulation of muscle tissue. Electrodes (12) of an electrode array (13) are activated in accordance with a sequence of activation patterns, each pattern defining a subset of the electrodes (12) to be activated, each subset consisting of at least one electrode (12), by providing an electrical muscle stimulation signal to the muscle tissue via the subset of electrodes (12). Alternately with said activating of electrodes (12), a response signal associated with the respective activation pattern is received from a sensor (30; 12). Optionally, at least one electrode (12) is then selected for stimulation, corresponding to a location determined as being suitable for stimulation, and the muscle tissue is stimulated. The process may be repeated in order to track the location suitable for stimulation in a dynamic situation. Optionally, the orientation of body part is estimated from the measured response signals.

Methods are disclosed for treating a subject having a disease or disorder comprising providing the subject with an acoustic energy stimulus derived from a disease-specific, condition-specific, endogenous mediator-specific or pharmacologic agent-specific neurogram in an amount and manner effective to treat the disease or disorder.

A device for stimulating neurons that includes a stimulation unit that applies mechanically tactile and/or thermal stimuli to the body surface of a patient that stimulate neurons with a pathologically synchronous and oscillatory neural activity. The device includes a measuring unit that records measurement signals of neural activity of the stimulated neurons, and a controller that controls the stimulation unit and analyzes the measurement signals. The controller actuates the stimulation unit to scan at least one part of the body surface of the patient along a path and thereby periodically applies stimuli and also selects two regions or more regions on the patient's body surface along the path where the phase synchronization between the periodic application of the stimuli and the neural activity of the stimulated neurons have a local maximum using the measurement signals. The stimuli are then applied in a delayed manner in the two regions.

A method to increase the overall hemodynamic efficacy of cardiopulmonary resuscitation (CPR) by alternating between chest compression-decompression cycles optimized to either cardiac output or venous return. The phases of cardiac output and venous return enhancement may themselves by adjusted in their duration and character. The method may enhance mechanical and manual techniques delivered to the anterior or circumferential chest, and be synchronized to adjunctive techniques such as airway, ventilatory or abdominal therapies.

A method of treatment by vibration stimulation is provided. The method includes providing an expandable stimulation member adapted to impart vibrations to body tissue of a human subject; introducing the stimulation member into a body cavity of the human subject; expanding the stimulation member to a volume such that the stimulation member abuts against body tissue within the body cavity; bringing the stimulation member to vibrate such that vibrations are imparted to the body tissue in the body cavity of the human subject according to a vibration pattern, wherein the vibration pattern includes a main periodic element of a first frequency and an excitation stimulus of a second frequency higher than the first frequency.

A walking assistance method may include: computing an amount of exercise of a user based on a biosignal of the user; adjusting a pattern of an assist parameter based on the amount of exercise; and/or generating a force corresponding to the amount of exercise, based on the adjusted pattern. A walking assistance apparatus may include: a pattern adjuster configured to compute an amount of exercise of a user based on a biosignal of the user; and/or a driver configured to generate a force corresponding to the amount of exercise based on a pattern of an assist parameter based on the amount of exercise.

In accordance with one or more embodiments and corresponding disclosure, various non-limiting systems, devices, and methods are described in connection with an assistive support device that provides feedback to a user. In an aspect, disclosed is a system comprising, a first sensor component that generates a first set of sensor data based on a first set of force applied to an assistive support device. The system also comprises a data repository component that stores a first set of sensor data provided by the assistive support device. Furthermore, in an aspect, the system comprises a feedback component that employs a feedback mechanism based on an occurrence of a value of an applied force to the assistive support device of the first set of force applied being greater than or less than a threshold value of an applied force.