Systems and devices for regulation of self-management of a medication schedule are provided. A system can include a pill dispenser cap, a plurality of insulating layers; a near field communication (NFC) tag, and a pill dispenser. The system can further include a graphical user interface (GUI), and first and second mobile devices each having a display unit, a sensor, a processor, and a computer readable medium.

The present invention features a compound of formula I:

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or a pharmaceutically acceptable salt thereof, where R.sub.1, R.sub.2, R.sub.3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.

Disclosed herein are modular container systems having child-resistant containers, tray inserts and tray frames. Also disclosed are methods using the modular container systems and methods of storing substances in containers. The containers have a container base and a container cap and provide for child-resistant containers. A user can releasably remove the container cap from container base with a squeeze and lift sequence. For example, the user squeezes opposite sides of the container base, which releases a locking mechanism and allows for removal of the cap by lifting or pulling the container cap off from the container base. The components of the modular container system are modular and stackable. The modular system allow for organized, efficient, accessible and storage of the child-resistant containers. The modular container system also allows for easy counting, sorting and processing of the containers.

Disclosed herein are modular container systems having child-resistant containers, tray inserts and tray frames. Also disclosed are methods using the modular container systems and methods of storing substances in containers. The containers have a container base and a container cap and provide for child-resistant containers. A user can releasably remove the container cap from container base with a squeeze and lift sequence. For example, the user squeezes opposite sides of the container base, which releases a locking mechanism and allows for removal of the cap by lifting or pulling the container cap off from the container base. The components of the modular container system are modular and stackable. The modular system allow for organized, efficient, accessible and storage of the child-resistant containers. The modular container system also allows for easy counting, sorting and processing of the containers.

A modular dispenser includes a cartridge configured to hold a plurality of pills. The cartridge includes an opening through which the at least one pill is configured to pass under an influence of gravity. A dispensing base is configured to removably receive the cartridge. The dispensing base includes a funnel with a funnel inlet proximate the opening of the cartridge and a funnel outlet spaced apart from the funnel inlet. A dispensing assembly is rotatably coupled to the dispensing base. The dispensing base also includes a catch configured to receive the at least one pill when the catch is proximate the funnel outlet and rotate away from the funnel outlet to a position from which the at least one pill is retrievable by a user.

A modular dispenser includes a cartridge configured to hold a plurality of pills. The cartridge includes an opening through which the at least one pill is configured to pass under an influence of gravity. A dispensing base is configured to removably receive the cartridge. The dispensing base includes a funnel with a funnel inlet proximate the opening of the cartridge and a funnel outlet spaced apart from the funnel inlet. A dispensing assembly is rotatably coupled to the dispensing base. The dispensing base also includes a catch configured to receive the at least one pill when the catch is proximate the funnel outlet and rotate away from the funnel outlet to a position from which the at least one pill is retrievable by a user.

This invention provides a blister pack dosage form container, comprising an advanceable blister pack holder, comprising a series of access portals sized to accommodate pass-through of at least one dosage form contained within a multi-dosage form containing blister pack located within said holder proximally therethrough upon engagement of an appropriate depilling structure, wherein said advanceable blister pack holder optionally accommodates upright positioning of said dosage forms and said depilling structure displaces said dosage form laterally. The invention also provides a multi-dosage form container, comprising an advanceable multi-sectioned dosage form holder, comprising a series of access portals sized to accommodate pass-through of at least one dosage form contained within said multi-sectioned dosage form holder proximally therethrough upon alignment with an appropriate egress structure, optionally wherein said multi-sectioned dosage form holder accommodates upright positioning of said dosage forms such that said egress structure provides for lateral displacement of said at least one dosage form; and a lockable outer container, comprising a tamper proof casing within which the multi-sectioned dosage form holder is contained. Kits containing the blister pack dosage form container and multi-dosage form containers are also described.

A container lid assembly includes a movable lid unit, a cylindrical locking device, an arcuate plate, an annular cover, and a container. A rotation of the movable lid unit and subsequent operations show change of symbol of a symbol ring and capsules in the container can be taken out of the tubular insertion member. It can correctly record the number of times of the container being opened. The container lid assembly further provides a space for storing another kind of medicine in the lid.

A container lid assembly includes a movable lid unit, a cylindrical locking device, an arcuate plate, an annular cover, and a container. A rotation of the movable lid unit and subsequent operations show change of symbol of a symbol ring and capsules in the container can be taken out of the tubular insertion member. It can correctly record the number of times of the container being opened. The container lid assembly further provides a space for storing another kind of medicine in the lid.

Disclosed is an elongate form medicament carrier and a medicament dispenser. The medicament carrier has a first end, a second end, and a central portion, and carrying multiple distinct medicament dose portions, the medicament dose portions consisting of a first set and a second set of medicament dose portions, the first set of medicament dose portions distributed in a first portion of the elongate form medicament carrier between the first end and the central portion of the elongate form medicament carrier and containing a medicament active, or a mixture of medicament actives, and the second set of medicament dose portions distributed in a second portion of the elongate form medicament carrier between the second end and the central portion of the elongate form medicament carrier and containing a medicament active, or a mixture of medicament actives, wherein the dose portions in the second set of medicament dose portions are different from the dose portions in the first set of medicament dose portions.