A balloon type liquid medicine injector for continuously injecting a small amount of liquid medicine into a body of a patient is disclosed as to be easily assembled and to prevent unnecessary dead space while being inflated after a liquid medicine is injected, so as to be miniaturized. When a tube body is provided outside a fixed pipe, both ends of the tube body are folded and inserted into both ends of the fixed tube, to remove the dead space while being inserted inside the case. In addition, in a state where the both ends of the tube body are folded and inserted into the both ends of the fixed tube, an injection mechanism for injecting the liquid medicine or a stopper mechanism are coupled while pressing the tube body folded inward, so that a separate packing is unnecessary and the airtightness is maintained.

Disclosed herein are methods of reducing muscle contraction in a diaphragm or peripheral muscle(s) of a patient sufficient to permit a surgical procedure. The methods may comprise the step of administering an oxime or pharmaceutically acceptable salt thereof to a subject in need thereof in an amount sufficient to achieve said reduced muscle contraction/neuromuscular blockade. Kits and articles of manufacture comprising a container having a label and a composition are also disclosed.

Disclosed herein are methods of reducing muscle contraction in a diaphragm or peripheral muscle(s) of a patient sufficient to permit a surgical procedure. The methods may comprise the step of administering an oxime or pharmaceutically acceptable salt thereof to a subject in need thereof in an amount sufficient to achieve said reduced muscle contraction/neuromuscular blockade. Kits and articles of manufacture comprising a container having a label and a composition are also disclosed.

The present invention relates to an outer cap device for a container having a neck, the opening of which is closed off by a closure device comprising a region (13) to be safeguarded. According to the invention, this outer cap device comprises: - a main body (14) intended to be fastened to the neck of the container, this main body (14) comprising an upper wall (18) having an opening intended to be positioned next to this region (13) to be safeguarded when the main body (14) is fastened to the neck of this container so as to leave said region (13) to be safeguarded freely accessible, - a cover (16) comprising an internal face (22) and an inner skirt (23) extending from this internal face (22), the internal face (22) being closed in line with this inner skirt (23), this inner skirt (23) being designed to pass through the opening in the upper wall (18) of the main body (14) and surround the region (13) to be safeguarded when the cover (16) is in the closed position, - holding means for locking the cover (16) in the closed position and allowing it to be unlocked to pass into the open position, these holding means being configured to press the free end of the inner skirt (23) against the closure device in the closed position of the cover (16) so as to form a sealed barrier surrounding the region (13) to be safeguarded, in order to limit exchanges from this region (13) to be safeguarded with the single interior volume of the inner skirt (23).

An approach for determining material compatibility for components of a drug delivery system is provided that includes using surface zeta-potential analytical method to evaluate surface interactions between a desired molecule and at least one material present within a given IV-bag system.

A medicament filling system (30) provides medicament to a delivery device (20). The medicament filling system (30) comprises a main housing (40) having an air pump (42), a vial adapter (44) that is configured to engage a vial (10) containing medicament, the vial adapter (44) being in communication with the air pump (42), a syringe housing (46) that carries a syringe (70), the syringe housing (46) being in selective communication with the vial adapter (44) and the delivery device (20), and a valve (60) that locks and unlocks movement of a plunger (72) in the syringe (70).

The present invention relates to a method and a system (400) for filling a closed container (200) with a fixative solution. The system comprises a container (200) comprising a container body (230) for receiving a biological specimen, a lid (220) for selectively closing the container body (230) and a port (100) forming a unidirectional barrier in a direction from the inside (IC) to the outside (OC) of the closed container (200). The system further comprises a dispensing apparatus (500) having a filling nozzle (300) for dispensing the fixative solution. The filling nozzle (300) is relatively moveable with respect to the container (200) between a retracted position and a filling position to fill the container (200) with the fixative solution.

A transport or packaging container accommodating a plurality of supporting structures for closures, for transporting or packaging closures for closing cartridges for use in pharmaceutical, medical or cosmetic applications, in which the transport or packaging container is box-shaped and includes a bottom, which is closed or sealed by a seal, upstanding lower side-walls extending essentially perpendicularly from the bottom, a circumferential supporting step extending horizontally from the upstanding lower side-walls, upper side-walls extending upward from said circumferential supporting step, and a circumferential flange formed at upper ends of the upper side-walls; and the plurality of supporting structures for closures is accommodated inside the transport or packaging container.

A 3-D flexible bag to be filled with a biopharmaceutical product is formed by assembling of two wall elements and two gussets. At least one connection port is provided, for filling and/or emptying. A substantially parallelepipedal configuration is obtained in a filled state thanks to the unfolding of the gussets combined with the folding of flaps of the two wall elements. A transverse weld, formed at one end, connects the two wall elements of the bag and extends continuously, keeping in a folded-flat state:—an elongate edge portion of one gusset;—an elongate edge portion of the other gusset. This transverse weld has a length corresponding to a determined dimension of the flexible bag in the parallelepipedal configuration.

Glass articles with coatings are disclosed herein. According to embodiments, a glass article may include a glass body comprising glass and having a first surface and a second surface opposite the first surface, wherein the first surface is an exterior surface of the glass body. A coating disposed on at least a portion of the exterior surface of the glass body. The coated glass article may have an effective throughput rate greater than or equal to 1.10×R.sub.T, wherein R.sub.T is the effective throughput rate of an uncoated glass article in units of parts per minute (ppm).