The generation device includes: an illuminating unit including light-emitting units simultaneously illuminate a surface of a medicine from irradiation directions different from each other; an imaging unit acquires a plurality of first images of the medicine corresponding to the respective wavelength bands from an imaging element; an image generating unit generates, based on the first images acquired by the imaging unit, a second image to which emphasis processing for emphasizing the engraved mark or the print has been applied; and a processing control unit controls the image generating unit to generate the second image when two or more of output values of the respective first images are equal to or more than a threshold, and controls the image generating unit not to generate the second image when less than two of the output values of the respective first images are equal to or more than the threshold.

An example device includes at least one three-dimensional (3D) printed tablet and a 3D-printed production support structure. Each 3D-printed tablet includes an excipient material and an active ingredient. The 3D-printed support structure includes a 3D-printed planar structure comprising the excipient material and at least one 3D-printed connecting member comprising the excipient material. The planar structure includes at least one aperture, each aperture corresponding to one of the at least one 3D-printed tablet. The connecting member detachably connects the at least one 3D-printed tablet with the 3D-printed planar structure and positions the at least one 3D-printed tablets within the apertures.

Ingestible devices capable of delivering a dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are disclosed. A removably attachable storage reservoir configured to be used with an ingestible device and capable of storing dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are also disclosed.

Provided is a gelatin supply device for a softgel encapsulation machine, the device having multiple spreader boxes provided on a guide having adjustment holes arranged in an arc shape to form multiple gelatin sheets, the device being further provided with a printing unit between the provided spreader boxes to print an information mark on an upper surface of a gelatin sheet while forming the gelatin sheet, the device forming a shell of a capsule by covering the information mark with another gelatin sheet.

Ingestible devices capable of delivering a dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are disclosed. A removably attachable storage reservoir configured to be used with an ingestible device and capable of storing dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are also disclosed.

An apparatus that includes a partial power source including a first material and a second material, the partial power source configured to generate, upon contact with a conducting medium, a potential difference between the first material and the second material to provide power to a control device, and generate, using the first material and the second material, a current flow within the conducting medium, the current flow including information encoded based on a variable conductance between the first material and the second material.

Controlled activation identifiers for use in ingestible compositions, such as pharma-informatics enabled compositions, are provided. The identifiers include a controlled activation element that provides for activation of the identifier in response to the presence of a predetermined stimulus at a target site of interest. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.

The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also measure the conditions of the environment surrounding the system.

Embodiments of an apparatus, system and method for facilitating the tracking of consumable pharmaceutical articles are disclosed. A marking apparatus is configured to apply unique indelible identifiers to pharmaceutical articles at the point-of-sale. The indelible identifiers on the articles are visually or electronically readable to allow each respective article to be traced with respect to its manufacturer, prescribing physician, patient to whom it was prescribed, dispensing location, expiration date, dosage, or some combination thereof. An associated system and method may involve the provision of a remote database element configured to be in network communication between the marking apparatus, manufacturer, distributor, prescriber, dispensing location, scanning tool, or some combination thereof. The indelible identifier may initially be generated by the apparatus and then obtained and recorded by the remote database element. Alternative, the indelible identifier may initially be generated and recorded by the remote database element, then provided to the marking apparatus.

The present disclosure includes ingestible devices. In some examples, an ingestible device is presented that includes a framework, a control device secured to the framework, and a partial power source. The partial power source may include a first digestible material secured to the framework and electrically coupled to the control device, and a second digestible material electrically isolated from and dissimilar to the first digestible material, electrically coupled to the control device, and secured to the framework. The partial power source may be configured to provide power to the control device when the first and second digestible materials come in contact with a conductive fluid. The control device, after being provided power by the first and second digestible materials, may be configured to alter conductance between the first and second digestible materials to produce a current signature through the conductive fluid that is detectable by a receiver.