A latching mechanism suitable for suppository molds, where the latching mechanism is designed to assist the separation of mold when the latch is released. In embodiments, the latching mechanism has a lever portion on a first mold half and a catch portion on a second mold half. The lever portion is configured to impinge upon the catch portion to provide a force to bias the first mold half away from the second mold half. Other embodiments include methods of utilizing such a catching mechanism with a suppository mold.

Today's suppositories are typically packaged individually for digital administration into the anal canal of a patient. A suppository applicator described herein, which works with individually packaged suppositories, can alternatively be shipped in a prepackaged operational arrangement with a suppository to enable the patient to administer the suppository through use of the applicator in a single operation after opening a hygienic wrapper containing the applicator-suppository combination. A method for manufacturing a suppository includes manufacturing the suppository in the presence of and in contact with an element configured to be used to insert the suppository into a body cavity. The method may include using the element to define a shape of the suppository during the manufacturing. The resulting applicator-suppository combination is more hygienic and easier to handle than the separate applicator and suppository and provides more efficiency from time of opening the packaging to time of commencing administration of the suppository

Today's suppositories are typically packaged individually for digital administration into the anal canal of a patient. A suppository applicator described herein, which works with individually packaged suppositories, can alternatively be shipped in a prepackaged operational arrangement with a suppository to enable the patient to administer the suppository through use of the applicator in a single operation after opening a hygienic wrapper containing the applicator-suppository combination. A method for manufacturing a suppository includes manufacturing the suppository in the presence of and in contact with an element configured to be used to insert the suppository into a body cavity. The method may include using the element to define a shape of the suppository during the manufacturing. The resulting applicator-suppository combination is more hygienic and easier to handle than the separate applicator and suppository and provides more efficiency from time of opening the packaging to time of commencing administration of the suppository

A latching mechanism suitable for suppository molds, where the latching mechanism is designed to assist the separation of mold when the latch is released. In embodiments, the latching mechanism has a lever portion on a first mold half and a catch portion on a second mold half. The lever portion is configured to impinge upon the catch portion to provide a force to bias the first mold half away from the second mold half. Other embodiments include methods of utilizing such a catching mechanism with a suppository mold.

A latching mechanism suitable for suppository molds, where the latching mechanism is designed to assist the separation of mold when the latch is released. In embodiments, the latching mechanism has a lever portion on a first mold half and a catch portion on a second mold half. The lever portion is configured to impinge upon the catch portion to provide a force to bias the first mold half away from the second mold half. Other embodiments include methods of utilizing such a catching mechanism with a suppository mold.

The present invention is directed toward an apparatus and method for consumer manufacture of suppositories for rectal or vaginal delivery allowing for the removal of formed suppositories while mitigating the deformation or damage to the formed suppositories when removed.

The present invention is directed toward an apparatus and method for consumer manufacture of suppositories for rectal or vaginal delivery allowing for the removal of formed suppositories while mitigating the deformation or damage to the formed suppositories when removed.

A production line is, suitable for the production of medicinal products that include at least one active ingredient. The production line includes an extruder for producing an extrudate from the active ingredient and at least one excipient intended to form an encapsulating matrix of the active ingredient, and a cooling member for cooling the extrudate at the outlet of the extruder. The extruder includes a barrel and at least two parallel screws housed in the barrel and interpenetrating with one another to mix the or each active ingredient with the or each excipient. The barrel is oriented vertically and the footprint occupied by the production line is less than 0.5 m.sup.2.

A production line is, suitable for the production of medicinal products that include at least one active ingredient. The production line includes an extruder for producing an extrudate from the active ingredient and at least one excipient intended to form an encapsulating matrix of the active ingredient, and a cooling member for cooling the extrudate at the outlet of the extruder. The extruder includes a barrel and at least two parallel screws housed in the barrel and interpenetrating with one another to mix the or each active ingredient with the or each excipient. The barrel is oriented vertically and the footprint occupied by the production line is less than 0.5 m.sup.2.

In a method and a corresponding device for producing an extrudate, starting products are introduced into an extrusion container, heated, and homogeneously intermixed by dual asymmetric centrifugation of the extrusion container. The extrusion container is rotated about a primary rotation axis that extends outside the extrusion container, and is simultaneously rotated about a secondary rotation axis that extends through the extrusion container and is situated at an acute angle with respect to the primary rotation axis. Lastly, the intermixed starting products are jointly extruded from the extrusion container. The method and the corresponding device are particularly suitable for processing small and very small substance quantities.